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Portage Pathophysiology Exam 1 | Module 1 Problem Set

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Prepare for Portage Pathophysiology Exam 1 and the Module 1 Problem Set with a focused review of foundational pathophysiology concepts, disease processes, and clinical principles.

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Portage Pathophysiology Exam 1, Portage Pathophysiology Module 1 Prob
lem Set, portage pathophysiology exam 1, portage pathophysiology exam
1
Study online at https://quizlet.com/_jtmwki

1. Definition of defined as not only the cellular and organ changes that occur with disease, but
Pathophysiology also the effects that these changes have on total body function.

2. 5 etiologic fac- Biological: bacteria and viruses
tors and an ex- Physical: trauma, burns, and radiation
ample of each Chemical: poisons, drugs
One's genetic inheritance
Nutritional excesses or deficiencies

3. 2 types of risk congenital factors (present at birth) or acquired (occurring after birth)
factors

4. Difference be- Morphology - fundamental structure or form of cells or tissues (includes the gross
tween morpholo- and microscopic changes)
gy and histology Histology - study of the cells and extracellular matrix of body tissues (at the tissue
level)

5. Signs and symp- Signs - objective and can be seen or measured. Elevated temp, leg edema, and
toms changes in pupil size.
symptoms - subjective. pain, trouble breathing, dizziness.

6. 3 important Patient history, physical examination, and diagnostic tests.
processes when
coming to a diag-
nosis?

7. Validity, reliabil- Validity - how a tool measure what it is intended to measure.
ity, sensitivity,
and specificity Reliability - likelihood the same result occurring with multiple testing.
definitions.
Sensitivity - the proportion of people with a disease who are positive for that



, Portage Pathophysiology Exam 1, Portage Pathophysiology Module 1 Prob
lem Set, portage pathophysiology exam 1, portage pathophysiology exam
1
Study online at https://quizlet.com/_jtmwki
disease.

Specificity - are people without the disease who are negative on a given test.

8. Define epidemi- Epidemiology is the study of disease occurrence in human populations. It tracks,
ology and name age, race, dietary habits, lifestyle, or geographic location.
some thing that it
tracks.

9. Difference be- Incidence - the number of new cases in a population
tween incidence
and prevalence Prevalence - the number of people with the disease in a population in a given time

10. Define Mortality Mortality - the statistics that deal with cause of death in a population
and Morbidity
Morbidity is the effect of illness on one's life.

11. Define Primary, Primary: remove risk factors to prevent disease from occurring. Examples - yearly
secondary, and check up, daily vitamin, vaccination, wearing seatbelts or helmets.
tertiary preven-
tion and give an Secondary: detect and treat disease early, usually while the disease is asymp-
example of each. tomatic and curable. Example - pap smears, checking bp and cholesterol and
colonoscopy screening. Usually all done by setting of a physician.

Tertiary: occurs after a diagnosis has been made and clinical interventions are
needed to reduce complications.

12. Why is evidence Evidence-based practice is the conscientious, explicit, and judicious use of current
based practice best evidence in making decisions about the care of individual patients. This is to
important? counteract "the way things have always been done," and to practice based on
clinical research.



, Portage Pathophysiology Exam 1, Portage Pathophysiology Module 1 Prob
lem Set, portage pathophysiology exam 1, portage pathophysiology exam
1
Study online at https://quizlet.com/_jtmwki
13. what are the Nucleus, cytoplasm, and plasma membrane
3 primary struc-
tures of the cell?

14. What is the func- control center of the cell and contains DNA and RNA
tion of the nucle-
us?

15. Name 3 struc- chromatin, nucleolus, and nuclear envelope
tures within the
nucleus

16. what organelles Ribosomes, golgi apparatus, Endoplasmic reticulum, mitochondria and lyso-
are located in the somes.
cytoplasm?

17. Roles of ribo- Ribosomes - synthesize proteins
somes, rough ER Rough ER - contain ribosomes and functions to synthesize lysosomal enzymes.
and smooth ER The smooth ER does not have ribosomes and is the site for lipid, lipoprotein, and
steroid hormones synthesis.

18. What is the func- Lysosomes (acid hydrolases) - digestive system of the cell. Break down cell excess,
tion of the lyso- worn cellular substance and foreign substances.
somes, peroxi-
somes, and mito- Peroxisomes - smaller than lysosomes and function in the control of free radicals.
chondria?
mitochondria - power plant. produce
ATP.

19. What is con- contains a network of microtubules, microfilaments, intermediate filaments, and
tained in the thick filaments. They control cell shape and movement.
cytoskeleton and

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