NU 553 Comprehensive Resource To Help You Ace Exams Includes Frequently Tested Questions With ELABORATED 100% Correct COMPLETE SOLUTIONS Guaranteed Pass First Attempt!! Current Update!!

NU 553 Comprehensive Resource To Help You Ace Exams Includes Frequently Tested Questions With ELABORATED 100% Correct COMPLETE SOLUTIONS Guaranteed Pass First Attempt!! Current Update!! 1. What does ADME stand for? A. Absorption, Distribution, Metabolism, Elimination B. Absorption, Digestion, Metabolism, Excretion C. Administration, Distribution, Metabolism, Elimination D. Absorption, Distribution, Medication, Excretion Correct Answer: A. Absorption, Distribution, Metabolism, Elimination 2. What do the 4 processes of ADME determine? A. Drug toxicity and adverse reactions B. Bioavailability: how much of the drug reaches its target and how long it persists there C. The drug's therapeutic index D. The drug's route of administration Correct Answer: B. Bioavailability: how much of the drug reaches its target and how long it persists there 3. For oral administration, a drug must be ___ and ___. A. Lipid-soluble and acidic B. Soluble (dissolvable) and stable in stomach fluid C. Water-insoluble and stable in bile D. Protein-bound and highly concentrated Correct Answer: B. Soluble (dissolvable) and stable in stomach fluid 4. Which of the following are examples of transdermal patches? A. Nicotine, fentanyl, clonidine, estrogen, scopolamine, selegiline, and methylphenidate B. Insulin, heparin, warfarin, and aspirin C. Acetaminophen, ibuprofen, naproxen, and aspirin D. Amoxicillin, penicillin, cephalexin, and azithromycin Correct Answer: A. Nicotine, fentanyl, clonidine, estrogen, scopolamine, selegiline, and methylphenidate 5. Which of the following is a challenge of administration by injection? A. Slow delivery allows time to reverse an overdose B. Does not require sterile technique C. Quick delivery leaves little time to respond to adverse reactions or accidental overdose D. The medication can easily be recalled after administration Correct Answer: C. Quick delivery leaves little time to respond to adverse reactions or accidental overdose 6. Which of the following are the 4 membranes that drugs may pass through? A. Cell membranes, capillary walls, blood-brain barrier, and placental barrier B. Skin, muscle, bone, and cartilage C. Liver, kidney, heart, and lungs D. Mucosal, gastric, intestinal, and renal membranes Correct Answer: A. Cell membranes, capillary walls, blood-brain barrier, and placental barrier 7. Most drugs pass through the ___, which is the primary site for ___. A. Kidney; drug excretion B. Heart; drug distribution C. Liver; drug metabolism D. Lungs; drug absorption Correct Answer: C. Liver; drug metabolism 8. What are the liver's primary mechanisms for metabolizing drugs? A. Renin-angiotensin enzymes B. Cytochrome P-450 enzymes C. Digestive enzymes D. Pancreatic enzymes Correct Answer: B. Cytochrome P-450 enzymes 9. Once in the liver, ___ convert drugs into ___ ___. A. Hormones; inactive compounds B. Enzymes; active metabolites C. Proteins; inactive metabolites D. Electrolytes; active compounds Correct Answer: B. Enzymes; active metabolites 10. What are active metabolites? A. An inactive form of a drug B. A toxic waste product C. A usable form of a drug D. A drug that cannot cross cell membranes Correct Answer: C. A usable form of a drug