NR 565 FINAL EXAM – ADV
PHARMACOLOGY FUNDAMENTALS –
(2026) ACTUAL QUESTIONS &
ANSWERS (CHAMBERLAIN) 100%
GUARANTEE PASS
NR565 ADVANCED PHARMACOLOGY
FUNDAMENTALS
Heart Failure Plan for CKD - CORRECT ANSWER -ACEI
or ARB as first line; can add CCB or thiazide diuretic
Heart Failure Plan for Pregnancy - CORRECT ANSWER -
Labetolol
Preganant women Use of Anticoagulants - CORRECT
ANSWER -Warfarin is contraindicated in this population.
Low-molecular weight (LMW) heparins and unfractionated
heparin are commonly used. Argatroban is a safe alternative.
,Older Adults Use of Anticoagulants - CORRECT ANSWER
-In this patient population, embolic stroke from atrial
fibrillation is more common. Usually anticoagulation is
recommended to reduce the risk, however therapy should be
individualized based on bleeding risk.
BreastFeeding Women Use of Anticoagulants - CORRECT
ANSWER -Data are lacking regarding safety of these
medications in this patient population. Warfarin and heparin
are both safe to use.
Infants Use of Anticoagulants - CORRECT ANSWER -
Heparin is commonly used in these patients needing
anticoagulation. Argatroban has been used successfully in
these patients with heparin-induced thrombocytopenia (HIT).
Warfarin can also be administered to these patients.
Children Use of Anticoagulants - CORRECT ANSWER -
Many anticoagulants can be used safely in this population,
just in smaller doses. Side-effect profiles are like those of
other populations.
,Colchicine (Colcrys/Mitigare) - CORRECT ANSWER -anti-
inflammatory agent with effects specific for gout. short term
to treat an acute gouty attack; long term use long term to
prevent attacks from recurring.
Colchicine MOA - CORRECT ANSWER -Exact mechanism
of action unknown in treatment of gout
Colchicine AE - CORRECT ANSWER -Rhabdomyolysis,
Diarrhea, nausea, vomiting, cramping, abdominal pain,
fatigue, headache, and pharyngolaryngeal pain
(Myelosuppression) leukopenia, granulocytopenia,
thrombocytopenia, and pancytopenia
Pharmacokinetics - CORRECT ANSWER -The process by
which drugs are absorbed, distributed within the body,
metabolized, and excreted.
Pharmacodynamics - CORRECT ANSWER -The study of
what the drug does to the body
, Factors Affecting Drug Absorption - CORRECT ANSWER -
Rate of dissolution Surface area
Blood flow
Lipid
solubility
pH
partitioning
Factors Affecting Drug Distribution - CORRECT ANSWER
-Blood flow to tissues
Ability to exit the vascular system
Blood-brain barrier
Protein-binding capacity
Xenobiotics - CORRECT ANSWER -substances that are
foreign to the body, usually synthetic chemical compounds;
medications are a common example
Cytochrome P450 (CYP450) - CORRECT ANSWER -
xenobiotic-metabolizing enzymes necessary for the
PHARMACOLOGY FUNDAMENTALS –
(2026) ACTUAL QUESTIONS &
ANSWERS (CHAMBERLAIN) 100%
GUARANTEE PASS
NR565 ADVANCED PHARMACOLOGY
FUNDAMENTALS
Heart Failure Plan for CKD - CORRECT ANSWER -ACEI
or ARB as first line; can add CCB or thiazide diuretic
Heart Failure Plan for Pregnancy - CORRECT ANSWER -
Labetolol
Preganant women Use of Anticoagulants - CORRECT
ANSWER -Warfarin is contraindicated in this population.
Low-molecular weight (LMW) heparins and unfractionated
heparin are commonly used. Argatroban is a safe alternative.
,Older Adults Use of Anticoagulants - CORRECT ANSWER
-In this patient population, embolic stroke from atrial
fibrillation is more common. Usually anticoagulation is
recommended to reduce the risk, however therapy should be
individualized based on bleeding risk.
BreastFeeding Women Use of Anticoagulants - CORRECT
ANSWER -Data are lacking regarding safety of these
medications in this patient population. Warfarin and heparin
are both safe to use.
Infants Use of Anticoagulants - CORRECT ANSWER -
Heparin is commonly used in these patients needing
anticoagulation. Argatroban has been used successfully in
these patients with heparin-induced thrombocytopenia (HIT).
Warfarin can also be administered to these patients.
Children Use of Anticoagulants - CORRECT ANSWER -
Many anticoagulants can be used safely in this population,
just in smaller doses. Side-effect profiles are like those of
other populations.
,Colchicine (Colcrys/Mitigare) - CORRECT ANSWER -anti-
inflammatory agent with effects specific for gout. short term
to treat an acute gouty attack; long term use long term to
prevent attacks from recurring.
Colchicine MOA - CORRECT ANSWER -Exact mechanism
of action unknown in treatment of gout
Colchicine AE - CORRECT ANSWER -Rhabdomyolysis,
Diarrhea, nausea, vomiting, cramping, abdominal pain,
fatigue, headache, and pharyngolaryngeal pain
(Myelosuppression) leukopenia, granulocytopenia,
thrombocytopenia, and pancytopenia
Pharmacokinetics - CORRECT ANSWER -The process by
which drugs are absorbed, distributed within the body,
metabolized, and excreted.
Pharmacodynamics - CORRECT ANSWER -The study of
what the drug does to the body
, Factors Affecting Drug Absorption - CORRECT ANSWER -
Rate of dissolution Surface area
Blood flow
Lipid
solubility
pH
partitioning
Factors Affecting Drug Distribution - CORRECT ANSWER
-Blood flow to tissues
Ability to exit the vascular system
Blood-brain barrier
Protein-binding capacity
Xenobiotics - CORRECT ANSWER -substances that are
foreign to the body, usually synthetic chemical compounds;
medications are a common example
Cytochrome P450 (CYP450) - CORRECT ANSWER -
xenobiotic-metabolizing enzymes necessary for the
