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Exam (elaborations)

Nursing Informatics Exam 2026

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Questions 1 - 200 & answers +explanations Advanced / Hard / Mixed Difficulty Comprehensive Review Covering Foundations, Data Standards, Clinical Systems, Telehealth, Ethics, and Emerging Technologies

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1




NURSING INFORMATICS EXAM
Questions 1 - 200
Advanced / Hard / Mixed Difficulty
Comprehensive Review Covering Foundations, Data Standards, Clinical Systems,
Telehealth, Ethics, and Emerging Technologies


1. Which of the following best defines nursing informatics as recognized by the
American Nurses Association (ANA)?
A. The use of computers to manage patient billing and insurance claims
B. The integration of nursing science, computer science, and information science
to manage and communicate data, information, knowledge, and wisdom in
nursing practice
C. The replacement of nursing judgment with automated clinical decision support
systems
D. The application of technology to streamline hospital administration and staffing
Valid answer: B
Explanation: The ANA defines nursing informatics as the specialty that
integrates nursing science, computer science, and information science to manage
and communicate data, information, knowledge, and wisdom in nursing practice.
Option A is too narrow, focusing only on billing; option C is false; and option D
describes only a subset of informatics applications.


2. In the Data-Information-Knowledge-Wisdom (DIKW) framework, a patient's
blood pressure reading of 140/90 mmHg represents which level?
A. Data
B. Information
C. Knowledge
D. Wisdom

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Valid answer: A
Explanation: In the DIKW framework, data are raw, unprocessed facts and
figures. A single blood pressure reading of 140/90 mmHg is a discrete data point.
Information is data that has been interpreted and given meaning, such as
identifying the reading as elevated. Knowledge is the synthesis of information, and
wisdom is the application of knowledge in a clinical context.


3. Which of the following is an example of "wisdom" in nursing informatics?
A. A nurse documenting a patient's vital signs in the electronic health record (EHR)
B. A nurse interpreting a set of lab results as indicating a possible infection
C. A nurse recognizing a pattern of elevated blood glucose readings and adjusting
insulin administration based on clinical judgment
D. A nurse entering a medication order into the computerized provider order
entry (CPOE) system
Valid answer: C
Explanation: Wisdom is the highest level of the DIKW framework and involves
the application of knowledge, experience, and insight to make sound clinical
decisions. Adjusting insulin based on a pattern of glucose readings demonstrates
the use of knowledge and judgment to improve patient outcomes. Documentation
and interpretation are examples of data and information, respectively.


4. Which of the following is a recognized core competency domain for nursing
informatics as identified by the TIGER (Technology Informatics Guiding Education
Reform) initiative?
A. Basic computer skills
B. Information management skills
C. Information literacy
D. All of the above
Valid answer: D

,3



Explanation: The TIGER initiative and related frameworks (TANIC, NICA) identify
that nurses require basic computer competencies, information literacy, and
information management skills to effectively use informatics in practice.


5. An informatics nurse specialist is leading the implementation of a new
electronic health record (EHR) system. Which role is specific to her qualifications
in this process?
A. Entering patient data into the new system
B. Training all staff on the basic functions of the new system
C. Designing the system's clinical workflow to align with nursing practice and
safety standards
D. Providing technical support for hardware issues
Valid answer: C
Explanation: A core role of the informatics nurse specialist is to bridge clinical
practice and technology by designing and optimizing clinical workflows within
information systems. This requires specialized knowledge in both nursing and
informatics. While they may be involved in training or data entry, workflow design
is a function specific to their expertise.


6. What is the primary purpose of a Clinical Decision Support System (CDSS)?
A. To replace the healthcare provider's clinical judgment
B. To provide alerts, reminders, and evidence-based recommendations to assist in
clinical decision-making
C. To manage hospital finances and billing
D. To facilitate communication between patients and providers via telehealth
Valid answer: B
Explanation: A CDSS is a tool that analyzes data to help healthcare providers
make clinical decisions by providing alerts, reminders, and evidence-based

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recommendations. It is designed to support, not replace, clinical judgment.
Managing finances and facilitating telehealth are functions of other systems.


7. Computerized Provider Order Entry (CPOE) systems have revolutionized
healthcare by:
A. Replacing the need for nurses to transcribe orders
B. Ensuring standardized, legible, and complete orders, and reducing medication
errors
C. Automating patient discharge instructions
D. Allowing providers to bill for services directly
Valid answer: B
Explanation: CPOE has significantly improved patient safety by reducing errors
associated with illegible handwriting, incomplete orders, and transcription
mistakes. It helps to standardize the ordering process and integrates with CDSS to
check for drug interactions and allergies.


8. According to HIPAA and the HITECH Act, which of the following is considered
Protected Health Information (PHI)?
A. A patient's name and medical record number
B. A patient's diagnosis and treatment plan
C. A patient's Social Security number
D. All of the above
Valid answer: D
Explanation: PHI includes any individually identifiable health information held or
transmitted by a covered entity or its business associate, in any form or medium.
This includes names, geographic data, dates, phone numbers, Social Security
numbers, medical record numbers, and health information such as diagnoses and
treatment plans.

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