ABSITE EXAM PREP TEST BANK VERIFIED
QUESTIONS AND CORRECT ANSWERS
●● Breast: What are contraindications to BCT (lumpectomy) in stage I
breast cancer (and what specifically is not)?
Answer: 1) prior irradiation;
2) pos margins;
3) inflammatory;
4) pregnancy (unless 3rd trimester)
●● Breast: what are the axillary node levels (1-3, and one more
category)?
Answer: 1 - lateral to pec minor;
2 - beneath pec minor;
3 - medial to pec minor;
Rotter's Nodes - between pec major and pec minor
●● Breast: when is SNLB indicated (size, nodes, tumor status,
metastatic risk)>?
Answer: >1 cm, no positive nodes (obviously), primary tumor present,
low risk of axillary mets,
●● Breast: what do you do if you can't find radiotracer dye in SNLB?
,Answer: have to do formal ALND
●● Breast: what is treatment for DCIS in male/female?
Answer: female -- BCT + xrt OR mastectomy; male -- mastectomy
●● Breast: what is not needed for patient with negative SLNB?
Answer: ALND -- just do BCT or mastectomy depending on tumor is
fine
●● Breast: what patient would get only mastectomy/BCT + tamoxifen
for 5 years (4 characteristics)?
Answer: negative SLN, old, ER+, and tumor <2 cm
●● Breast: what patient would get mastectomy/BCT + tamoxifen for 5
years plus chemo (4 characteristics)?
Answer: negative SLN, young, ER+, and tumor >1cm
●● Breast: what are 3 chemo agents used for breast CA typically?
Answer: 1) adriamycin; 2) cyclophosphamide; 3) taxol
●● Breast: what patient would get mastectomy/BCT + chemo (no
tamoxifen)?
Answer: negative SLN, ER-
,●● Breast: what is main SE of taxol?
Answer: taxol - neuropathy
●● Breast: what is main SE of adriamycin (doxorubacin)?
Answer: cardiomyopathy
●● Breast: what is treatment for inflammatory breast cancer (in order)?
Answer: neoadjuvant chemo, then mastectomy (mod radical), then XRT
●● Breast: what options are available for breast mass post neoadjuvant
therapy?
Answer: same as de novo breast cancer -- BCT or mastectomy -- if
tumor shrunk and now amenable to BCT, that's fine, even if it was big
before and needed mastectomy based on size
●● Breast: LCIS -- who primarily gets this, what is most important
characteristic, what % get cancer, where, and what type?
Answer: - pre-menopausal
- NOT premalignant itself
- 30% lifetime risk
70% ductal CA
, ●● Breast: LCIS -- what % have synchronous cancer?
Answer: 5%
●● Breast: LCIS -- what is treatment (4 possibility, 2 things not needed
ever)?
Answer: 1) Need to resect the lesion but do not need neg margins
2) nothing and careful F/U
3) Hormonal therapy
-(pre-meno: tamoxifen; Post-meno: raloxifene)
4) bilateral subcutaneous mastectomy (no ALND)
●● Breast: What are the benign proliferative breast lesions that have
increased risk of CA? (3)
Tx?
Answer: - LCIS
- Atypical ductal hyperplasia
- atypical lobular hyperplasia
Tx: resect the lesion w/ (-) margins
●● Breast: for atypical ductal hyperplasia; atypical lobular hyperplasia;
LCIS, how are these characterized and what treatment should be
considered?
Answer: benign proliferative dz. Incr risk of CA.
QUESTIONS AND CORRECT ANSWERS
●● Breast: What are contraindications to BCT (lumpectomy) in stage I
breast cancer (and what specifically is not)?
Answer: 1) prior irradiation;
2) pos margins;
3) inflammatory;
4) pregnancy (unless 3rd trimester)
●● Breast: what are the axillary node levels (1-3, and one more
category)?
Answer: 1 - lateral to pec minor;
2 - beneath pec minor;
3 - medial to pec minor;
Rotter's Nodes - between pec major and pec minor
●● Breast: when is SNLB indicated (size, nodes, tumor status,
metastatic risk)>?
Answer: >1 cm, no positive nodes (obviously), primary tumor present,
low risk of axillary mets,
●● Breast: what do you do if you can't find radiotracer dye in SNLB?
,Answer: have to do formal ALND
●● Breast: what is treatment for DCIS in male/female?
Answer: female -- BCT + xrt OR mastectomy; male -- mastectomy
●● Breast: what is not needed for patient with negative SLNB?
Answer: ALND -- just do BCT or mastectomy depending on tumor is
fine
●● Breast: what patient would get only mastectomy/BCT + tamoxifen
for 5 years (4 characteristics)?
Answer: negative SLN, old, ER+, and tumor <2 cm
●● Breast: what patient would get mastectomy/BCT + tamoxifen for 5
years plus chemo (4 characteristics)?
Answer: negative SLN, young, ER+, and tumor >1cm
●● Breast: what are 3 chemo agents used for breast CA typically?
Answer: 1) adriamycin; 2) cyclophosphamide; 3) taxol
●● Breast: what patient would get mastectomy/BCT + chemo (no
tamoxifen)?
Answer: negative SLN, ER-
,●● Breast: what is main SE of taxol?
Answer: taxol - neuropathy
●● Breast: what is main SE of adriamycin (doxorubacin)?
Answer: cardiomyopathy
●● Breast: what is treatment for inflammatory breast cancer (in order)?
Answer: neoadjuvant chemo, then mastectomy (mod radical), then XRT
●● Breast: what options are available for breast mass post neoadjuvant
therapy?
Answer: same as de novo breast cancer -- BCT or mastectomy -- if
tumor shrunk and now amenable to BCT, that's fine, even if it was big
before and needed mastectomy based on size
●● Breast: LCIS -- who primarily gets this, what is most important
characteristic, what % get cancer, where, and what type?
Answer: - pre-menopausal
- NOT premalignant itself
- 30% lifetime risk
70% ductal CA
, ●● Breast: LCIS -- what % have synchronous cancer?
Answer: 5%
●● Breast: LCIS -- what is treatment (4 possibility, 2 things not needed
ever)?
Answer: 1) Need to resect the lesion but do not need neg margins
2) nothing and careful F/U
3) Hormonal therapy
-(pre-meno: tamoxifen; Post-meno: raloxifene)
4) bilateral subcutaneous mastectomy (no ALND)
●● Breast: What are the benign proliferative breast lesions that have
increased risk of CA? (3)
Tx?
Answer: - LCIS
- Atypical ductal hyperplasia
- atypical lobular hyperplasia
Tx: resect the lesion w/ (-) margins
●● Breast: for atypical ductal hyperplasia; atypical lobular hyperplasia;
LCIS, how are these characterized and what treatment should be
considered?
Answer: benign proliferative dz. Incr risk of CA.
