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Galen College of Nursing NUR 210 Newest Exam
Preparation With Complete Questions And Correct Answers
With Rationales Already Graded A+ Brand New Version!!
1. What are the four phases of pharmacokinetics?
A) Absorption, digestion, metabolism, excretion
B) Absorption, distribution, metabolism, excretion
C) Administration, distribution, metabolism, elimination
D) Absorption, distribution, metabolism, elimination
Answer: B) Absorption, distribution, metabolism, excretion
Rationale: Pharmacokinetics is the study of drug movement
throughout the body, encompassing four distinct phases: absorption
(entry into the bloodstream), distribution (movement to tissues),
metabolism (biotransformation), and excretion (elimination from the
body).
2. A patient asks the nurse why oral medications take longer to work
than intravenous medications. What is the best response?
A) "Oral medications are weaker than IV medications."
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B) "Oral medications must be absorbed through the GI tract before
entering the bloodstream."
C) "IV medications are more dangerous, so they work faster."
D) "Your body rejects oral medications more slowly."
Answer: B) "Oral medications must be absorbed through the GI tract
before entering the bloodstream."
Rationale: Intravenous (IV) administration bypasses the absorption
phase entirely, allowing the drug to enter systemic circulation directly
and achieve 100% bioavailability. Oral medications must first dissolve in
the GI tract, pass through the intestinal mucosa, and undergo first-pass
metabolism before reaching systemic circulation.
3. Which organ is primarily responsible for drug metabolism?
A) Kidney
B) Liver
C) Heart
D) Lungs
Answer: B) Liver
Rationale: The liver is the primary site of drug metabolism
(biotransformation). The cytochrome P450 enzyme system located in
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the liver is responsible for the chemical alteration of many drugs to
facilitate their excretion.
4. What is the primary organ responsible for drug excretion?
A) Liver
B) Kidney
C) Intestine
D) Skin
Answer: B) Kidney
Rationale: The kidneys are the primary organs responsible for drug
excretion. Drugs and their metabolites are eliminated from the body
through urine. Impaired renal function requires dose adjustment to
prevent toxicity.
5. A patient with chronic kidney disease has a reduced glomerular
filtration rate (GFR). What effect will this have on drug therapy?
A) Decreased drug half-life
B) Increased drug elimination
C) Increased drug half-life and risk of accumulation
D) No effect on drug levels
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Answer: C) Increased drug half-life and risk of accumulation
Rationale: A reduced GFR indicates impaired renal function, meaning
drugs are excreted more slowly from the body. This prolongs the drug's
half-life and increases the risk of drug accumulation and toxicity. Dose
adjustment is often required.
6. A loading dose is best described as:
A) A smaller than normal dose given to start therapy
B) A larger than normal dose given to rapidly achieve therapeutic
levels
C) The dose given at bedtime
D) The dose given after meals
Answer: B) A larger than normal dose given to rapidly achieve
therapeutic levels
Rationale: A loading dose is a larger than normal initial dose of a drug
used to rapidly achieve a therapeutic concentration in the blood. This is
particularly useful when a quick response is required.
7. When should a trough drug level be drawn?
A) 1-2 hours after the medication is administered
B) Just before the next dose of medication is due
Galen College of Nursing NUR 210 Newest Exam
Preparation With Complete Questions And Correct Answers
With Rationales Already Graded A+ Brand New Version!!
1. What are the four phases of pharmacokinetics?
A) Absorption, digestion, metabolism, excretion
B) Absorption, distribution, metabolism, excretion
C) Administration, distribution, metabolism, elimination
D) Absorption, distribution, metabolism, elimination
Answer: B) Absorption, distribution, metabolism, excretion
Rationale: Pharmacokinetics is the study of drug movement
throughout the body, encompassing four distinct phases: absorption
(entry into the bloodstream), distribution (movement to tissues),
metabolism (biotransformation), and excretion (elimination from the
body).
2. A patient asks the nurse why oral medications take longer to work
than intravenous medications. What is the best response?
A) "Oral medications are weaker than IV medications."
,2|Page
B) "Oral medications must be absorbed through the GI tract before
entering the bloodstream."
C) "IV medications are more dangerous, so they work faster."
D) "Your body rejects oral medications more slowly."
Answer: B) "Oral medications must be absorbed through the GI tract
before entering the bloodstream."
Rationale: Intravenous (IV) administration bypasses the absorption
phase entirely, allowing the drug to enter systemic circulation directly
and achieve 100% bioavailability. Oral medications must first dissolve in
the GI tract, pass through the intestinal mucosa, and undergo first-pass
metabolism before reaching systemic circulation.
3. Which organ is primarily responsible for drug metabolism?
A) Kidney
B) Liver
C) Heart
D) Lungs
Answer: B) Liver
Rationale: The liver is the primary site of drug metabolism
(biotransformation). The cytochrome P450 enzyme system located in
,3|Page
the liver is responsible for the chemical alteration of many drugs to
facilitate their excretion.
4. What is the primary organ responsible for drug excretion?
A) Liver
B) Kidney
C) Intestine
D) Skin
Answer: B) Kidney
Rationale: The kidneys are the primary organs responsible for drug
excretion. Drugs and their metabolites are eliminated from the body
through urine. Impaired renal function requires dose adjustment to
prevent toxicity.
5. A patient with chronic kidney disease has a reduced glomerular
filtration rate (GFR). What effect will this have on drug therapy?
A) Decreased drug half-life
B) Increased drug elimination
C) Increased drug half-life and risk of accumulation
D) No effect on drug levels
, 4|Page
Answer: C) Increased drug half-life and risk of accumulation
Rationale: A reduced GFR indicates impaired renal function, meaning
drugs are excreted more slowly from the body. This prolongs the drug's
half-life and increases the risk of drug accumulation and toxicity. Dose
adjustment is often required.
6. A loading dose is best described as:
A) A smaller than normal dose given to start therapy
B) A larger than normal dose given to rapidly achieve therapeutic
levels
C) The dose given at bedtime
D) The dose given after meals
Answer: B) A larger than normal dose given to rapidly achieve
therapeutic levels
Rationale: A loading dose is a larger than normal initial dose of a drug
used to rapidly achieve a therapeutic concentration in the blood. This is
particularly useful when a quick response is required.
7. When should a trough drug level be drawn?
A) 1-2 hours after the medication is administered
B) Just before the next dose of medication is due
