TEST BANK FOR PATHOPHYSIOLOGY
THE BIOLOGIC BASIS FOR DISEASE IN
ADULTS AND CHILDREN 8 TH EDITION
BY KATHRYN L. MCCANCE ACTUAL
EXAM PAPER 2026 QUESTIONS WITH
ANSWERS GRADED A+
◍ Receptors.
Answer: Proteins that bind to hormones, neurotransmitters, antigens etc.
◍ Nitric oxide influx.
Answer: The entry of nitric oxide into the cell, which is not associated with
cellular swelling due to ATP loss.
◍ Exudation.
Answer: Formation of pus during inflammatory response.
◍ 20. Active transport occurs across which type of membranes?a.Membranes
that have a higher concentration of the solute on the outside of the
cellb.Membranes that are semipermeable to water and small electrically
uncharged moleculesc.Membranes that have receptors that are capable of
binding with the substances to be transportedd.Membranes that have a cell
membrane that is hydrophobic rather than hydrophilic.
Answer: ANS: CSome molecules are moved into the cell by mechanisms of
active transport, which require receptors that are capable of recognizing and
binding with the substance to be transported. Diffusion is the movement of a
solute molecule from an area of greater solute concentration to an area of
lesser solute concentration. Hydrostatic pressure is the mechanical force of
, water pushing against cellular membranes. Osmosis is the movement of
water down a concentration gradient; that is, across a semipermeable
membrane from a region of higher water concentration to a lower water
concentrationPTS: 1 REF: Page 28
◍ Acute acidosis.
Answer: Condition that can lead to hyperkalemia.
◍ TP53.
Answer: gene where resistance to apoptosis occurs
◍ Pyrexia.
Answer: Abnormal elevation of body temperature
◍ Which of the following plasma systems that regulate inflammation is most
responsible fordestroying and removing microorganisms through
opsonization and cell lysis?A) Kinin systemB) Clotting systemC)
Complement systemD) Erythrocyte.
Answer: C
◍ Renal compensation.
Answer: The kidney's response to maintain electrolyte balance during
conditions of metabolic alkalosis.
◍ Sonic Hedgehog Signaling.
Answer: Involved in eye development and brain separation.
◍ Acid-Base Regulation.
Answer: Managed by lungs through elimination of carbon dioxide.
◍ Chemical signaling.
Answer: The process by which cells communicate through the release and
reception of chemical signals.
◍ Polyploid Cell.
Answer: Cell with more than 23 pairs of chromosomes.
◍ divergence.
Answer: ability of branching axons to influence many different neurons
,◍ Osmosis.
Answer: Movement of water across a semipermeable membrane.
◍ Which term is used to describe a NEW in SECONDARY or additional
problem that arises after the original disease has been established?
A. Symptoms
B. Occurrence
C. Manifestations
D. Complication.
Answer: D. Complication
◍ Sodium-Potassium (Na+-K+) Pump.
Answer: A plasma membrane pump that transports sodium out of the cell
and potassium into the cell, which fails due to a reduction in ATP levels.
◍ Translocation.
Answer: Interchange of genetic material between chromosomes.
◍ gastroparesis.
Answer: full filling after dinner- autonomic neuropathy which is a
microvascular problem
◍ Chromosome.
Answer: Rod or threadlike organelle of a cell that carries the DNA and
genes
◍ Adenosine triphosphate (ATP).
Answer: A molecule whose loss during ischemia causes cells to swell due to
the failure of the sodium-potassium pump, leading to an intracellular
accumulation of sodium and calcium.
◍ Secondary prevention.
Answer: The early detection of disease through screening and early
treatment.
◍ Phases of catabolism.
Answer: Includes digestion, glycolysis, oxidation, citric acid cycle.
, ◍ Tibia fracture.
Answer: An example of a blunt force injury sustained in a skiing accident.
◍ Clinical manifestations of hypokalemia.
Answer: Include paralytic ileus, sinus bradycardia, and atrioventricular
block.
◍ Subdural Hematoma.
Answer: Blood collection between dura mater and brain.
◍ hormones from adrenal cortex.
Answer: glucocorticoids- mineralocorticoids- gonadocorticoids (sex
hormones)
◍ Monocyte.
Answer: A type of white blood cell that is not a granulocyte.
◍ Spondylolysis.
Answer: Degenerative process of the vertebral column and associated soft
tissue
◍ Pain Mechanism.
Answer: Prostaglandins directly affect nerve pain receptors.
◍ Hypercalcemia clinical manifestations.
Answer: Include calcium based kidney stones, lethargy, and bradycardia.
◍ Mycotic aneurysm.
Answer: Aneurysm that is caused by bacterial or fungal growth in the vessel
wall or infection of an arteriosclerotic aneurysm.
◍ inspiratory capacity.
Answer: the amount of air that can be inhaled from normal expiratory level
to the max amount
◍ type I DM.
Answer: deficit of insulin & amylin- severe insulin deficiency & excessive
fat breakdown & make ketoacids faster than body can remove them- excess
THE BIOLOGIC BASIS FOR DISEASE IN
ADULTS AND CHILDREN 8 TH EDITION
BY KATHRYN L. MCCANCE ACTUAL
EXAM PAPER 2026 QUESTIONS WITH
ANSWERS GRADED A+
◍ Receptors.
Answer: Proteins that bind to hormones, neurotransmitters, antigens etc.
◍ Nitric oxide influx.
Answer: The entry of nitric oxide into the cell, which is not associated with
cellular swelling due to ATP loss.
◍ Exudation.
Answer: Formation of pus during inflammatory response.
◍ 20. Active transport occurs across which type of membranes?a.Membranes
that have a higher concentration of the solute on the outside of the
cellb.Membranes that are semipermeable to water and small electrically
uncharged moleculesc.Membranes that have receptors that are capable of
binding with the substances to be transportedd.Membranes that have a cell
membrane that is hydrophobic rather than hydrophilic.
Answer: ANS: CSome molecules are moved into the cell by mechanisms of
active transport, which require receptors that are capable of recognizing and
binding with the substance to be transported. Diffusion is the movement of a
solute molecule from an area of greater solute concentration to an area of
lesser solute concentration. Hydrostatic pressure is the mechanical force of
, water pushing against cellular membranes. Osmosis is the movement of
water down a concentration gradient; that is, across a semipermeable
membrane from a region of higher water concentration to a lower water
concentrationPTS: 1 REF: Page 28
◍ Acute acidosis.
Answer: Condition that can lead to hyperkalemia.
◍ TP53.
Answer: gene where resistance to apoptosis occurs
◍ Pyrexia.
Answer: Abnormal elevation of body temperature
◍ Which of the following plasma systems that regulate inflammation is most
responsible fordestroying and removing microorganisms through
opsonization and cell lysis?A) Kinin systemB) Clotting systemC)
Complement systemD) Erythrocyte.
Answer: C
◍ Renal compensation.
Answer: The kidney's response to maintain electrolyte balance during
conditions of metabolic alkalosis.
◍ Sonic Hedgehog Signaling.
Answer: Involved in eye development and brain separation.
◍ Acid-Base Regulation.
Answer: Managed by lungs through elimination of carbon dioxide.
◍ Chemical signaling.
Answer: The process by which cells communicate through the release and
reception of chemical signals.
◍ Polyploid Cell.
Answer: Cell with more than 23 pairs of chromosomes.
◍ divergence.
Answer: ability of branching axons to influence many different neurons
,◍ Osmosis.
Answer: Movement of water across a semipermeable membrane.
◍ Which term is used to describe a NEW in SECONDARY or additional
problem that arises after the original disease has been established?
A. Symptoms
B. Occurrence
C. Manifestations
D. Complication.
Answer: D. Complication
◍ Sodium-Potassium (Na+-K+) Pump.
Answer: A plasma membrane pump that transports sodium out of the cell
and potassium into the cell, which fails due to a reduction in ATP levels.
◍ Translocation.
Answer: Interchange of genetic material between chromosomes.
◍ gastroparesis.
Answer: full filling after dinner- autonomic neuropathy which is a
microvascular problem
◍ Chromosome.
Answer: Rod or threadlike organelle of a cell that carries the DNA and
genes
◍ Adenosine triphosphate (ATP).
Answer: A molecule whose loss during ischemia causes cells to swell due to
the failure of the sodium-potassium pump, leading to an intracellular
accumulation of sodium and calcium.
◍ Secondary prevention.
Answer: The early detection of disease through screening and early
treatment.
◍ Phases of catabolism.
Answer: Includes digestion, glycolysis, oxidation, citric acid cycle.
, ◍ Tibia fracture.
Answer: An example of a blunt force injury sustained in a skiing accident.
◍ Clinical manifestations of hypokalemia.
Answer: Include paralytic ileus, sinus bradycardia, and atrioventricular
block.
◍ Subdural Hematoma.
Answer: Blood collection between dura mater and brain.
◍ hormones from adrenal cortex.
Answer: glucocorticoids- mineralocorticoids- gonadocorticoids (sex
hormones)
◍ Monocyte.
Answer: A type of white blood cell that is not a granulocyte.
◍ Spondylolysis.
Answer: Degenerative process of the vertebral column and associated soft
tissue
◍ Pain Mechanism.
Answer: Prostaglandins directly affect nerve pain receptors.
◍ Hypercalcemia clinical manifestations.
Answer: Include calcium based kidney stones, lethargy, and bradycardia.
◍ Mycotic aneurysm.
Answer: Aneurysm that is caused by bacterial or fungal growth in the vessel
wall or infection of an arteriosclerotic aneurysm.
◍ inspiratory capacity.
Answer: the amount of air that can be inhaled from normal expiratory level
to the max amount
◍ type I DM.
Answer: deficit of insulin & amylin- severe insulin deficiency & excessive
fat breakdown & make ketoacids faster than body can remove them- excess
