AQA GCSE COMBINED SCIENCE: TRILOGY
8464/B/1H BIOLOGY PAPER 1H PAPER
& MARK SCHEME FINAL TEST 2026
QUESTIONS WITH CORRECT ANSWERS
GRADED A+
◍ Digestive system- large intestine.
Answer: Removes excess water
◍ Name some stem cell uses.
Answer: Grow new brain cells, grow new bones, grow new organs
◍ The carbon cycle.
Answer: Returns carbon from organisms to the atmosphere as carbon
dioxide to be used by plants in photosynthesis
◍ How does wind effect transpiration.
Answer: High wind, more transpiration because wind will be brushing
against leaf, so diffusion will play a part here
◍ What do inherited genes control?.
Answer: The characteristics you develop. Genes code for proteins.Some
characteristics controlled by single geneMost characteristics controlled by
several INTERACTING GENES
◍ What three things do new drugs need to be tested for.
Answer: Toxicity-how much should be taken before side effects occur
efficacy- how efficient it is. Does it work better or worse than what's on the
marketdose-how much do you need to take for the drug to be effective
◍ Magnification equation.
, Answer: Magnification= image size/actual object size
◍ Risk factors for cardiovascular disease.
Answer: Smoking, high blood pressure, too much salt or fat in diet
◍ Eg of pathogens.
Answer: Virus bacteria fungi Protist
◍ Give 3 details of Asexual reproduction.
Answer: -One parent -Genetically identical offspring-clone-Happens by
mitosis
◍ Apex predators.
Answer: Carnivores with no predators
◍ What is matabrolism and give eg.
Answer: Rate that chemical reactions take place in our body eg. Glucose
turned into starch, cellulose or glycogen. Fatty acids made into lipids.
Amino acids made into proteins. All involves energy
◍ What is the diaphragm?.
Answer: A plastic cup that fits over the cervix (opening to the womb) to
form a barrier.
◍ Light microscope- how many um in 1 mm.
Answer: 1000 um
◍ Vein properties.
Answer: Carry deoxygenated blood back to heart so have valves. Thin walls
and thin lumen
◍ What are chromosomes?.
Answer: Long molecules of DNA inside a nucleus.23 pairs inside the
nucleus of body cells.
◍ How does temperature effect enzyme activity.
Answer: Low temp-not enough energyPeak- optimal tempAfter peak-
enzymes get denaturedGraph is a curve steeper after the peak
,◍ What is the contraceptive patch?.
Answer: Contains same hormones as the pill. Patch is stuck under the skin
(5cm x 5cm). Each patch lasts a week.
◍ Light and photosynthesis- why should you leave the plant for a few minutes
before starting to count bubbles.
Answer: It takes time for the plant to adjust to the light/temperature and for
photosynthesis to reach the correct rate
◍ How can type II diabetes be treated?.
Answer: It can be controlled by eating a carbohydrate controlled diet and
getting regular exercise.
◍ Investigating osmosis- what are the results.
Answer: High concentration of sugar in solution- water moves out of potato
cells into the solution.potato gets smaller, low concentration potato gets
bigger
◍ How do you make a stem cell.
Answer: Take nuclei out of a egg cell take nuclei from the patients cell and
insert into empty egg egg starts to develop into a embryo.
◍ Requirements for photosynthesis.
Answer: Chlorophyll (the green pigment in leaves) WaterCarbon
dioxideSunlight
◍ How does a line transect work?.
Answer: 1. Stretch a tape between 2 points.2. Sample organisms at regular
intervals along the line using a quadrat
◍ Malaria - type of pathogen, spread, implications and damage.
Answer: Parasite spread by female mosquito drinking your blood
implications-high fever, sweats, chills, headache, vomiting, chest and
Muscle pain damage, can be lethal
◍ What is the role of progesterone in the menstrual cycle?.
Answer: Produced by the ovary by the remains of the follicle. Maintains the
, lining of the uterus. When the level of progesterone falls the lining of the
uterus breaks down. Inhibits the release of LH and FSH.
◍ How can we use a genetically modified bacterium to treat people with
diabetes?.
Answer: A genetically modified bacterium produces human insulin which
can be harvested, purified and used to treat people
◍ Explain Antibiotic Resistance.
Answer: Bacteria DNA RANDOMLY MUTATES. Taking antibiotics
creates a selective pressure as the environment changes. Selects the resistant
strain as better adapted. This can lead to antibiotic resistant strains. More
likely to survive and reproduce. Gene for antibiotic resistance increases in
the population.
◍ What are the advantages and disadvantages of a kidney transplant over
dialysis?.
Answer: Kidney transplants are a cure, but they can be rejected. Patients are
treated with immunosuppressants. People are not always on the donor list,
relatives have to agree to the donation. Transplants are cheaper than dialysis
to the NHS. Long waiting lists for transplants. Patients have to spend 3-4
hours a day, 3 x a week which can have a negative impact on their quality of
life.
◍ Digestive system- salivary gland.
Answer: Produce amylase
◍ HIV - type of pathogen, spread, implications and damage.
Answer: Virus, spread by unprotected sex. Sharing needles, child birth from
mother to child, infected blood, breastfeeding from infected mother.
Implications- attracts white blood cells which are a important part of
immune response. damage- can develop into aids
◍ What does phloem do.
Answer: Carey's ions and food in downwards direction fro leaf to roots for it
to be stored eg. In potatoes
8464/B/1H BIOLOGY PAPER 1H PAPER
& MARK SCHEME FINAL TEST 2026
QUESTIONS WITH CORRECT ANSWERS
GRADED A+
◍ Digestive system- large intestine.
Answer: Removes excess water
◍ Name some stem cell uses.
Answer: Grow new brain cells, grow new bones, grow new organs
◍ The carbon cycle.
Answer: Returns carbon from organisms to the atmosphere as carbon
dioxide to be used by plants in photosynthesis
◍ How does wind effect transpiration.
Answer: High wind, more transpiration because wind will be brushing
against leaf, so diffusion will play a part here
◍ What do inherited genes control?.
Answer: The characteristics you develop. Genes code for proteins.Some
characteristics controlled by single geneMost characteristics controlled by
several INTERACTING GENES
◍ What three things do new drugs need to be tested for.
Answer: Toxicity-how much should be taken before side effects occur
efficacy- how efficient it is. Does it work better or worse than what's on the
marketdose-how much do you need to take for the drug to be effective
◍ Magnification equation.
, Answer: Magnification= image size/actual object size
◍ Risk factors for cardiovascular disease.
Answer: Smoking, high blood pressure, too much salt or fat in diet
◍ Eg of pathogens.
Answer: Virus bacteria fungi Protist
◍ Give 3 details of Asexual reproduction.
Answer: -One parent -Genetically identical offspring-clone-Happens by
mitosis
◍ Apex predators.
Answer: Carnivores with no predators
◍ What is matabrolism and give eg.
Answer: Rate that chemical reactions take place in our body eg. Glucose
turned into starch, cellulose or glycogen. Fatty acids made into lipids.
Amino acids made into proteins. All involves energy
◍ What is the diaphragm?.
Answer: A plastic cup that fits over the cervix (opening to the womb) to
form a barrier.
◍ Light microscope- how many um in 1 mm.
Answer: 1000 um
◍ Vein properties.
Answer: Carry deoxygenated blood back to heart so have valves. Thin walls
and thin lumen
◍ What are chromosomes?.
Answer: Long molecules of DNA inside a nucleus.23 pairs inside the
nucleus of body cells.
◍ How does temperature effect enzyme activity.
Answer: Low temp-not enough energyPeak- optimal tempAfter peak-
enzymes get denaturedGraph is a curve steeper after the peak
,◍ What is the contraceptive patch?.
Answer: Contains same hormones as the pill. Patch is stuck under the skin
(5cm x 5cm). Each patch lasts a week.
◍ Light and photosynthesis- why should you leave the plant for a few minutes
before starting to count bubbles.
Answer: It takes time for the plant to adjust to the light/temperature and for
photosynthesis to reach the correct rate
◍ How can type II diabetes be treated?.
Answer: It can be controlled by eating a carbohydrate controlled diet and
getting regular exercise.
◍ Investigating osmosis- what are the results.
Answer: High concentration of sugar in solution- water moves out of potato
cells into the solution.potato gets smaller, low concentration potato gets
bigger
◍ How do you make a stem cell.
Answer: Take nuclei out of a egg cell take nuclei from the patients cell and
insert into empty egg egg starts to develop into a embryo.
◍ Requirements for photosynthesis.
Answer: Chlorophyll (the green pigment in leaves) WaterCarbon
dioxideSunlight
◍ How does a line transect work?.
Answer: 1. Stretch a tape between 2 points.2. Sample organisms at regular
intervals along the line using a quadrat
◍ Malaria - type of pathogen, spread, implications and damage.
Answer: Parasite spread by female mosquito drinking your blood
implications-high fever, sweats, chills, headache, vomiting, chest and
Muscle pain damage, can be lethal
◍ What is the role of progesterone in the menstrual cycle?.
Answer: Produced by the ovary by the remains of the follicle. Maintains the
, lining of the uterus. When the level of progesterone falls the lining of the
uterus breaks down. Inhibits the release of LH and FSH.
◍ How can we use a genetically modified bacterium to treat people with
diabetes?.
Answer: A genetically modified bacterium produces human insulin which
can be harvested, purified and used to treat people
◍ Explain Antibiotic Resistance.
Answer: Bacteria DNA RANDOMLY MUTATES. Taking antibiotics
creates a selective pressure as the environment changes. Selects the resistant
strain as better adapted. This can lead to antibiotic resistant strains. More
likely to survive and reproduce. Gene for antibiotic resistance increases in
the population.
◍ What are the advantages and disadvantages of a kidney transplant over
dialysis?.
Answer: Kidney transplants are a cure, but they can be rejected. Patients are
treated with immunosuppressants. People are not always on the donor list,
relatives have to agree to the donation. Transplants are cheaper than dialysis
to the NHS. Long waiting lists for transplants. Patients have to spend 3-4
hours a day, 3 x a week which can have a negative impact on their quality of
life.
◍ Digestive system- salivary gland.
Answer: Produce amylase
◍ HIV - type of pathogen, spread, implications and damage.
Answer: Virus, spread by unprotected sex. Sharing needles, child birth from
mother to child, infected blood, breastfeeding from infected mother.
Implications- attracts white blood cells which are a important part of
immune response. damage- can develop into aids
◍ What does phloem do.
Answer: Carey's ions and food in downwards direction fro leaf to roots for it
to be stored eg. In potatoes
