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MSN 622 Final Exam 2026/2027 | 70+ Questions & Answers | Cardiology, Diabetes, Rheumatology, SLE, Sleep Apnea & Sexual Assault Care

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This MSN 622 Final Exam 2026/2027 study resource contains 70+ clinical, scenario-based questions with answers covering major concepts relevant to advanced nursing assessment, diagnosis, treatment, pharmacology, and patient management. The cardiovascular section addresses coronary artery disease, unstable angina and NSTEMI, troponin interpretation, ASCVD risk assessment, coronary artery calcium scoring, CABG, peripheral arterial disease and ankle-brachial index, hypertension, congestive heart failure, cardiomyopathy, myocarditis, atrial fibrillation, ECG interpretation, cardioversion, anticoagulation, and cardiovascular medications such as nitroglycerin, metoprolol, diltiazem, ACE inhibitors, aspirin, clopidogrel, and rivaroxaban. The endocrine and metabolic portion includes type 1 and type 2 diabetes mellitus, HbA1c, diabetic microvascular complications, peripheral neuropathy, insulin management, carbohydrate counting, renal monitoring, hypothyroidism, Hashimoto thyroiditis, thyroid antibodies, and related clinical decision-making. The document then expands into rheumatology with rheumatoid arthritis, fibromyalgia, systemic lupus erythematosus (SLE), DMARD therapy, methotrexate, hydroxychloroquine, anti-CCP antibodies, corticosteroid complications, joint involvement, and autoimmune disease assessment. Additional questions address obstructive sleep apnea and polysomnography, heat exhaustion and heat-related syncope, hydration and emergency management, as well as sexual assault examination, forensic evidence collection, SANE care, STI prophylaxis, HIV post-exposure management, emergency contraception, and follow-up care. For example, the later section includes clinical questions involving ceftriaxone, doxycycline, metronidazole, antiretroviral prophylaxis, pregnancy prevention, and management following sexual assault. The question-and-answer format makes the material useful for active recall and exam review because students encounter realistic clinical presentations and must connect symptoms, examination findings, ECGs, laboratory values, diagnostic tests, medications, and treatment decisions. The uploaded document identifies itself as MSN 622 Final 2026/2027 Exam Questions and Answers and as already graded A+, although it does not identify a university or institution. Relevant Students: MSN 622 students, Master of Science in Nursing students, graduate nursing students, advanced practice nursing students, nurse practitioner students, FNP students, adult-gerontology nursing students, advanced health assessment students, advanced pathophysiology students, and students reviewing cardiovascular, endocrine, rheumatology, sleep, emergency, and sexual-assault-care concepts. Keywords: MSN 622 final exam, MSN 622 exam questions and answers, MSN 622 final 2026, MSN 622 final 2027, MSN 622 study guide, MSN 622 practice questions, nursing final exam questions, graduate nursing exam, advanced nursing practice, nurse practitioner exam questions, cardiology nursing questions, coronary artery disease, congestive heart failure, atrial fibrillation, ECG interpretation, peripheral arterial disease, hypertension management, cardiovascular pharmacology, diabetes mellitus questions, diabetic neuropathy, Hashimoto thyroiditis, endocrine nursing questions, rheumatoid arthritis questions, fibromyalgia, systemic lupus erythematosus, SLE nursing questions, DMARD therapy, obstructive sleep apnea, polysomnography, heat exhaustion, sexual assault nursing care, SANE exam, STI prophylaxis, HIV post exposure prophylaxis, clinical case questions, nursing exam preparation

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MSN 622 Final 2026/2027 Exam
Questions and Answers |
Already Graded A+



A 65-year-old woman presents with intermittent, sudden-onset chest

pain and shortness of breath, which radiates to her left jaw and arm. A

history of present illness reveals that the pain initially occurred with

activity, but now it occurs throughout the day. A review of systems is

positive for tiring easily with mild physical activity. Her medical history is

significant for hypertension and type 2 diabetes mellitus. An

electrocardiogram (ECG) and cardiac enzyme markers are ordered.

Which of the following tests will be most helpful in differentiating unstable

,angina from a non-ST segment elevation myocardial infarction

(NSTEMI)? - ANSWER ✔✔Troponin I


A 55-year-old asymptomatic, female smoker, with an extensive family

history of premature coronary artery disease, presents to the office for

further cardiovascular risk stratification. Her 10-year ASCVD risk score

by the pool cohort equation is 5.3%, and she is concerned about testing

for further risk stratification as she is reluctant to take medications.

Which of the following is most appropriate to order to assist in treatment

decision making? - ANSWER ✔✔Coronary artery calcium scoring


A 51-year-old female patient presents with a chief complaint to shortness

of breath, which is present only on exertion. She is a cashier in a local

bank. Her history includes type 1 diabetes mellitus and hypertension.

She is an active smoker for fifteen years and smokes one pack per day.

Her BMI is 32.2. Her current medications include insulin, empagliflozin,

and lisinopril. An EKG is obtained in the office, which shows normal

sinus rhythm with heart rate 77/min. Evidence of left ventricular

hypertrophy is also present on the EKG. An exercise stress test is

scheduled, and the patient gets chest pain on the treadmill soon after it

is started. Her echo shows a left ventricular ejection fraction of 30%.

Cardiac catheterization is performed, which shows 3-vessel coronary

artery disease. Which of the following is the best strategy for this

,patient's mechanical heart disease? - ANSWER ✔✔Coronary artery

bypass graft (CABG)

A 65-year-old man presents for preoperative evaluation. He plans to

undergo bilateral total knee replacement for osteoarthritis, which has

markedly limited his mobility. All conservative measures for osteoarthritis

treatment have failed. He has medical history significant for

hypertension, hyperlipidemia, and smoking. He received one drug-

eluting stent to the left anterior descending artery four months ago for

stable ischemic heart disease. Which of the following is the best step

regarding this patient's clearance for surgery? - ANSWER ✔✔Defer

surgery for at least 2 months.

What is the most appropriate initial intervention for an older male who

complains of leg pain with walking and at night who has weak pulses in

both lower extremities and a reduced ankle-brachial index? -

ANSWER ✔✔Lifestyle modification


A 74-year-old woman smoker with hypertension was found to have weak

right lower extremity pulses with a right ankle-brachial index (ABI) of

0.75. She denies any pain with walking. What is the most appropriate

treatment? - ANSWER ✔✔Smoking cessation




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, A 65-year-old man who is a heavy smoker presents with a complaint of

pain in both legs when he walks. He claims he can only walk half a block

over the past few years without pain. He has been a smoker for 35 years

and also drinks alcohol. He does not have a history of hypertension or

heart disease. The ankle-brachial index in both legs is 0.70. What should

be done to lower this patient's myocardial infarction risk? - ANSWER

✔✔Start patient on aspirin or clopidogrel


A 65-year-old woman presents to the clinic for a 1-year follow-up and

medication management. Her medical history is significant for

congestive heart failure, hypertension, hyperlipidemia, diabetes mellitus

type 2, and chronic obstructive pulmonary disease (COPD). She has

smoked 2 packs of cigarettes for 45 years. She drinks alcohol socially.

Her current medications include lisinopril, hydrochlorothiazide,

atorvastatin, metformin, albuterol, and inhaled fluticasone. Per the

patient, she feels fine other than "some mild tingling in my feet." She

denies chest pain, dyspnea, palpitations, dizziness, and weakness. She

has not had laboratory work done in over 1 year. Her vital signs are

temperature 37 °C (98.6 °F), heart rate 77 bpm, respiratory rate 16

breaths/min, and blood pressure 155/89 mm Hg. A physical exam is

significant for absent bilateral pedal and posterior tibial artery pulses,

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