Causes of local ischemia
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Arterial obstruction
Venous occlusion
Capillary obstruction
Cardiac Edema
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, Gravity influences the distribution
Excess retention of Na+ and H2O by kidneys (large part)
Weak pumping leads to increase venous P (small part)
Cap is made of
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collagen and smooth muscle
stable clot formation
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secondary hemostasis
______ and _______ are related to greater blood flow than normal in the given tissue
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hyperemia and congestion
hemostasis in the wrong place at the wrong time
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, thrombosis
Anti-coagulatant functions of endothelium
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1. Inhibit platelets by hiding ECM
2. Inhibit coag factors w/ heparin like molecules, thrombomodulin, and TFPI
3. Fibrinolysis: TTPA
What is found in the core of atherosclerotic plaque?
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lipid debris
How can obesity contribute to generation of thrombi?
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1. Pro inflammatory and hypofibrinolytic effects
2. V-Leiden mutation
3. Stasis or stagnation of blood in the veins.
4. Increase platelet activation
5. Overproduction of plasminogen activator inhibitor-1, inhibits fibrinolysis
, Which of the following happens as part of primary homeostasis
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Platelet aggregation
(follows platelet activation, binding of fibrinogen)
the formation of the initial platelet plug is called ______?
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primary hemostasis
after platelet adhesion, platelets do what? this is also known as platelet activation
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change shape and secrete granule contents
the bends, respiratory distress, CNS problems, ischemic damage to long bones
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nitrogen emboli
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Arterial obstruction
Venous occlusion
Capillary obstruction
Cardiac Edema
Give this one a try later!
, Gravity influences the distribution
Excess retention of Na+ and H2O by kidneys (large part)
Weak pumping leads to increase venous P (small part)
Cap is made of
Give this one a try later!
collagen and smooth muscle
stable clot formation
Give this one a try later!
secondary hemostasis
______ and _______ are related to greater blood flow than normal in the given tissue
Give this one a try later!
hyperemia and congestion
hemostasis in the wrong place at the wrong time
Give this one a try later!
, thrombosis
Anti-coagulatant functions of endothelium
Give this one a try later!
1. Inhibit platelets by hiding ECM
2. Inhibit coag factors w/ heparin like molecules, thrombomodulin, and TFPI
3. Fibrinolysis: TTPA
What is found in the core of atherosclerotic plaque?
Give this one a try later!
lipid debris
How can obesity contribute to generation of thrombi?
Give this one a try later!
1. Pro inflammatory and hypofibrinolytic effects
2. V-Leiden mutation
3. Stasis or stagnation of blood in the veins.
4. Increase platelet activation
5. Overproduction of plasminogen activator inhibitor-1, inhibits fibrinolysis
, Which of the following happens as part of primary homeostasis
Give this one a try later!
Platelet aggregation
(follows platelet activation, binding of fibrinogen)
the formation of the initial platelet plug is called ______?
Give this one a try later!
primary hemostasis
after platelet adhesion, platelets do what? this is also known as platelet activation
Give this one a try later!
change shape and secrete granule contents
the bends, respiratory distress, CNS problems, ischemic damage to long bones
Give this one a try later!
nitrogen emboli
