NBME Pathology Final Exam – 2026–2027 Edition –
Pathology Actual Correct Questions with Verified
Answers Frequently tested
Introduction
This document contains pathology practice questions with concise
verified answers covering major organ systems and high-yield
disease processes commonly tested on NBME-style pathology
examinations. It includes topics such as inflammation, neoplasia,
hematology, renal pathology, pulmonary disease, cardiovascular
pathology, gastrointestinal disorders, endocrine pathology,
infectious diseases, and autoimmune conditions.
The material is organized in a question-and-answer format for
efficient review and self-assessment. It is intended as a
comprehensive revision resource focusing on frequently tested
pathology concepts.
Exam Questions and Answers
1: What is the primary pathological finding in Alzheimers disease?--
- correct precise answer ---
The primary pathological findings in Alzheimers disease are
neurofibrillary tangles and amyloid-beta plaques in the brain.
2: Which type of hypersensitivity reaction is associated with
contact dermatitis?--- correct precise answer ---
, Page 2 of 14
Contact dermatitis is associated with a type IV hypersensitivity
reaction.
3: What is the most common cause of community-acquired
pneumonia?--- correct precise answer --- The most common cause
of community-acquired pneumonia is Streptococcus pneumoniae.
4: What tumor marker is commonly elevated in hepatocellular
carcinoma?--- correct precise answer --- Alpha-fetoprotein (AFP) is
commonly elevated in hepatocellular carcinoma.
5: What is the characteristic histological feature of rheumatic heart
disease?--- correct precise answer --- The characteristic histological
feature of rheumatic heart disease is Aschoff bodies.
6: Which genetic disorder is characterized by the presence of a
trinucleotide repeat expansion?--- correct precise answer ---
Huntingtons disease is characterized by a trinucleotide repeat
expansion.
7: What is the most common type of renal stone?--- correct precise
answer ---
The most common type of renal stone is a calcium oxalate stone.