, PRINCIPLES of
General, Organic, & Biological Chemistry
Third Edition
Janice Gorzynski Smith
University of Hawai‘i at Ma-noa
ISTUDY
, PRINCIPLES OF GENERAL, ORGANIC, & BIOLOGICAL CHEMISTRY
Published by McGraw Hill LLC, 1325 Avenue of the Americas, New York, NY 10019. Copyright ©2023 by
McGraw Hill LLC. All rights reserved. Printed in the United States of America. No part of this publication may
be reproduced or distributed in any form or by any means, or stored in a database or retrieval system, without
the prior written consent of McGraw Hill LLC, including, but not limited to, in any network or other electronic
storage or transmission, or broadcast for distance learning.
Some ancillaries, including electronic and print components, may not be available to customers outside the
United States.
This book is printed on acid-free paper.
1 2 3 4 5 6 7 8 9 LWI 26 25 24 23 22
ISBN 978-1-265-15120-1
MHID 1-265-15120-2
Cover Image: David Merron Photography/Getty Images
All credits appearing on page or at the end of the book are considered to be an extension of the copyright page.
The Internet addresses listed in the text were accurate at the time of publication. The inclusion of a website does
not indicate an endorsement by the authors or McGraw Hill LLC, and McGraw Hill LLC does not guarantee the
accuracy of the information presented at these sites.
mheducation.com/highered
ISTUDY
, About the Author
Janice Gorzynski Smith was born in Schenectady, New York. She received an A.B.
degree summa cum laude in chemistry at Cornell University and a Ph.D. in Organic Chemistry
from Harvard University under the direction of Nobel Laureate E. J. Corey. During her tenure
with the Corey group she completed the total synthesis of the plant growth hormone gibberellic
acid.
Following her postdoctoral work, Jan joined the faculty of Mount Holyoke College, where
she was employed for 21 years. During this time, she was active in teaching organic chemistry
lecture and lab courses, conducting a research program in organic synthesis, and serving as
department chair. Her organic chemistry class was named one of Mount Holyoke’s “Don’t-miss
courses” in a survey by Boston magazine. After spending two sabbaticals amidst the natural
beauty and diversity of Hawai‘i in the 1990s, Jan and her family moved there permanently in
2000. She has been a faculty member at the University of Hawai‘i at Manoa, where she has
taught a one-semester organic and biological chemistry course for nursing students, as well as the
two-semester organic chemistry lecture and lab courses. In 2003, she received the Chancellor’s
Daniel C. Smith
Citation for Meritorious Teaching.
Jan resides in Hawai‘i with her husband Dan, an emergency medicine physician, pictured
with her at an event on Oahu. She has four children and nine grandchildren. When not teaching,
writing, or enjoying her family, Jan bikes, hikes, snorkels, and scuba dives in sunny Hawai‘i,
and time permitting, enjoys travel and Hawaiian quilting.
To my family
iii
ISTUDY
General, Organic, & Biological Chemistry
Third Edition
Janice Gorzynski Smith
University of Hawai‘i at Ma-noa
ISTUDY
, PRINCIPLES OF GENERAL, ORGANIC, & BIOLOGICAL CHEMISTRY
Published by McGraw Hill LLC, 1325 Avenue of the Americas, New York, NY 10019. Copyright ©2023 by
McGraw Hill LLC. All rights reserved. Printed in the United States of America. No part of this publication may
be reproduced or distributed in any form or by any means, or stored in a database or retrieval system, without
the prior written consent of McGraw Hill LLC, including, but not limited to, in any network or other electronic
storage or transmission, or broadcast for distance learning.
Some ancillaries, including electronic and print components, may not be available to customers outside the
United States.
This book is printed on acid-free paper.
1 2 3 4 5 6 7 8 9 LWI 26 25 24 23 22
ISBN 978-1-265-15120-1
MHID 1-265-15120-2
Cover Image: David Merron Photography/Getty Images
All credits appearing on page or at the end of the book are considered to be an extension of the copyright page.
The Internet addresses listed in the text were accurate at the time of publication. The inclusion of a website does
not indicate an endorsement by the authors or McGraw Hill LLC, and McGraw Hill LLC does not guarantee the
accuracy of the information presented at these sites.
mheducation.com/highered
ISTUDY
, About the Author
Janice Gorzynski Smith was born in Schenectady, New York. She received an A.B.
degree summa cum laude in chemistry at Cornell University and a Ph.D. in Organic Chemistry
from Harvard University under the direction of Nobel Laureate E. J. Corey. During her tenure
with the Corey group she completed the total synthesis of the plant growth hormone gibberellic
acid.
Following her postdoctoral work, Jan joined the faculty of Mount Holyoke College, where
she was employed for 21 years. During this time, she was active in teaching organic chemistry
lecture and lab courses, conducting a research program in organic synthesis, and serving as
department chair. Her organic chemistry class was named one of Mount Holyoke’s “Don’t-miss
courses” in a survey by Boston magazine. After spending two sabbaticals amidst the natural
beauty and diversity of Hawai‘i in the 1990s, Jan and her family moved there permanently in
2000. She has been a faculty member at the University of Hawai‘i at Manoa, where she has
taught a one-semester organic and biological chemistry course for nursing students, as well as the
two-semester organic chemistry lecture and lab courses. In 2003, she received the Chancellor’s
Daniel C. Smith
Citation for Meritorious Teaching.
Jan resides in Hawai‘i with her husband Dan, an emergency medicine physician, pictured
with her at an event on Oahu. She has four children and nine grandchildren. When not teaching,
writing, or enjoying her family, Jan bikes, hikes, snorkels, and scuba dives in sunny Hawai‘i,
and time permitting, enjoys travel and Hawaiian quilting.
To my family
iii
ISTUDY
