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Exam (elaborations)

Strasinger AUBF Cerebrospinal Fluid (CSF) Analysis – Comprehensive Practice Questions with Answers..

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This document contains a comprehensive collection of practice questions and answers covering cerebrospinal fluid (CSF) analysis from Strasinger’s Urinalysis and Body Fluids (AUBF). It reviews CSF anatomy and physiology, specimen collection and handling, cell counts, differential counts, protein analysis, meningitis, hemorrhage, cytology, quality control, and laboratory procedures for cerebrospinal fluid examination.

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Indicates disorders affecting blood-brain barrier or production of IgG within the CNS
if found in CSF


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Protein




<50 WBCs/uL with increased normal and reactive lymphocytes and plasma cells


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Multiple sclerosis




Lines the brain and the spinal cord

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Meninges




Result of an increased protein or lipid concentration; may also be indicative of
infection, cloudiness caused by presence of WBCs


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Cloudy, turbid, milky CSF




All diluents should be checked ____ for contamination by examining them in a counting
chamber under 400x magnification


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Biweekly




Include cytoplasmic vacuoles, nuclear clefting, prominent nucleoli, indistinct nuclear
and cytoplasmic borders, and cellular clumping that resembles malignancy


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Cellular distortion




Neutrophils may contain ___ following cytocentrifugation

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Cytoplasmic vacuoles




Due to protein (disorders affecting blood-brain barrier), clotting factors introduced
by traumatic tap


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Clotted appearance




A separate carbohydrate-deficient transferrin fraction; seen in CSF but not in serum


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Tau




These must be soaked in a bacterial solution for at least 15 minutes, thoroughly rinsed
with water and cleaned with isopropyl alcohol after every use


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Nondisposable counting chambers




Result of blood that has been present longer than that introduced by the traumatic
tap

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