NSG 318 EXAM 4 2026 STUDY GUIDE REVISION
SHEET CORE CONCEPT BREAKDOWN
◉ Indications for amoxicillin.
Answer: Otitis Media (middle ear infection), Tonsillitis, Sinusitis,
Gastric/duodenal ulcers, Skin, Respiratory and Urinary tract
infections (UTIs).
◉ Side Effects of amoxicillin.
Answer: Nausea, vomiting, diarrhea, rash.
◉ Adverse Reactions of amoxicillin.
Answer: Liver damage, blood disorders.
◉ Contraindications for amoxicillin.
Answer: Allergy to penicillins, severe renal impairment. Reduces
effectiveness of oral contraceptives.
◉ CAMS for amoxicillin.
Answer: St. John's Wort, Garlic - Reduced effectiveness, increased
bleeding risk.
,◉ Nursing Considerations for amoxicillin.
Answer: Assess for allergies to penicillins; monitor for signs of an
allergic reaction, GI upset, and superinfection. Caution with renal
impairment.
◉ Antibacterial: Third-generation Cephalosporin.
Answer: Prototype: ceftriaxone. MOA - Inhibits bacterial cell wall
synthesis causing cell lysis; bactericidal effect.
◉ Indications for ceftriaxone.
Answer: OM, Meningitis, Appendicitis, Gonorrhea, Septicemia,
Surgical infection prophylaxis, Skin, Respiratory, Bone/joint,
Gynecologic, and UTIs.
◉ Side Effects of ceftriaxone.
Answer: Diarrhea, nausea, rash, injection site reactions. Potential for
superinfections (noted by mouth sores).
◉ Adverse Reactions of ceftriaxone.
Answer: Liver dysfunction, kidney dysfunction, blood clotting
problems.
◉ Contraindications for ceftriaxone.
,Answer: Caution with severe liver impairment. Disulfiram-like
reaction: Can cause nausea, vomiting, flushing, headache, and
abdominal cramps when alcohol is consumed during treatment.
◉ CAMS for ceftriaxone.
Answer: Garlic, Ginseng - Reduced effectiveness, bleeding
complications.
◉ Nursing Considerations for ceftriaxone.
Answer: Monitor for signs of an allergic reaction, especially in those
with a history of cephalosporin allergies. Monitor liver and renal
function.
◉ Antibacterial Macrolides.
Answer: Prototype: azithromycin. MOA - Inhibits the steps of protein
synthesis; bacteriostatic or bactericidal effect.
◉ Indications for azithromycin.
Answer: Bacterial conjunctivitis, OM, Tonsillitis, Sinusitis, STIs, Skin
& Respiratory infections.
◉ Side Effects of azithromycin.
Answer: Diarrhea, nausea, abdominal pain, rash.
, ◉ Adverse Reactions of azithromycin.
Answer: QT prolongation, liver toxicity.
◉ Contraindications for azithromycin.
Answer: Allergy to macrolides, liver impairment, caution in heart
patients. Ideally take on an empty stomach.
◉ CAMS for azithromycin.
Answer: Grapefruit, St. John's Wort - Increased risk of QT
prolongation, reduced antibiotic effectiveness.
◉ Nursing Considerations for azithromycin.
Answer: Monitor for QT prolongation and liver function, especially
in those with a history of arrhythmias or liver impairment.
◉ Antibacterial: Tetracycline.
Answer: Prototype: doxycycline. MOA - Inhibits the steps of protein
synthesis; bacteriostatic or bactericidal.
◉ Indications for doxycycline.
Answer: Acne, Anthrax, Plague, Gingivitis, STIs, Rickettsia, Cholera,
Respiratory, Urinary tract, and Skin infections.
SHEET CORE CONCEPT BREAKDOWN
◉ Indications for amoxicillin.
Answer: Otitis Media (middle ear infection), Tonsillitis, Sinusitis,
Gastric/duodenal ulcers, Skin, Respiratory and Urinary tract
infections (UTIs).
◉ Side Effects of amoxicillin.
Answer: Nausea, vomiting, diarrhea, rash.
◉ Adverse Reactions of amoxicillin.
Answer: Liver damage, blood disorders.
◉ Contraindications for amoxicillin.
Answer: Allergy to penicillins, severe renal impairment. Reduces
effectiveness of oral contraceptives.
◉ CAMS for amoxicillin.
Answer: St. John's Wort, Garlic - Reduced effectiveness, increased
bleeding risk.
,◉ Nursing Considerations for amoxicillin.
Answer: Assess for allergies to penicillins; monitor for signs of an
allergic reaction, GI upset, and superinfection. Caution with renal
impairment.
◉ Antibacterial: Third-generation Cephalosporin.
Answer: Prototype: ceftriaxone. MOA - Inhibits bacterial cell wall
synthesis causing cell lysis; bactericidal effect.
◉ Indications for ceftriaxone.
Answer: OM, Meningitis, Appendicitis, Gonorrhea, Septicemia,
Surgical infection prophylaxis, Skin, Respiratory, Bone/joint,
Gynecologic, and UTIs.
◉ Side Effects of ceftriaxone.
Answer: Diarrhea, nausea, rash, injection site reactions. Potential for
superinfections (noted by mouth sores).
◉ Adverse Reactions of ceftriaxone.
Answer: Liver dysfunction, kidney dysfunction, blood clotting
problems.
◉ Contraindications for ceftriaxone.
,Answer: Caution with severe liver impairment. Disulfiram-like
reaction: Can cause nausea, vomiting, flushing, headache, and
abdominal cramps when alcohol is consumed during treatment.
◉ CAMS for ceftriaxone.
Answer: Garlic, Ginseng - Reduced effectiveness, bleeding
complications.
◉ Nursing Considerations for ceftriaxone.
Answer: Monitor for signs of an allergic reaction, especially in those
with a history of cephalosporin allergies. Monitor liver and renal
function.
◉ Antibacterial Macrolides.
Answer: Prototype: azithromycin. MOA - Inhibits the steps of protein
synthesis; bacteriostatic or bactericidal effect.
◉ Indications for azithromycin.
Answer: Bacterial conjunctivitis, OM, Tonsillitis, Sinusitis, STIs, Skin
& Respiratory infections.
◉ Side Effects of azithromycin.
Answer: Diarrhea, nausea, abdominal pain, rash.
, ◉ Adverse Reactions of azithromycin.
Answer: QT prolongation, liver toxicity.
◉ Contraindications for azithromycin.
Answer: Allergy to macrolides, liver impairment, caution in heart
patients. Ideally take on an empty stomach.
◉ CAMS for azithromycin.
Answer: Grapefruit, St. John's Wort - Increased risk of QT
prolongation, reduced antibiotic effectiveness.
◉ Nursing Considerations for azithromycin.
Answer: Monitor for QT prolongation and liver function, especially
in those with a history of arrhythmias or liver impairment.
◉ Antibacterial: Tetracycline.
Answer: Prototype: doxycycline. MOA - Inhibits the steps of protein
synthesis; bacteriostatic or bactericidal.
◉ Indications for doxycycline.
Answer: Acne, Anthrax, Plague, Gingivitis, STIs, Rickettsia, Cholera,
Respiratory, Urinary tract, and Skin infections.
