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NBME BIOCHEMISTRY SHELF EXAM 2026 PRACTICE TEST PACK COMPLETE SOLUTIONS VERIFIED INSIGHTS

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NBME BIOCHEMISTRY SHELF EXAM 2026 PRACTICE TEST PACK COMPLETE SOLUTIONS VERIFIED INSIGHTS

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NBME BIOCHEMISTRY SHELF EXAM 2026
PRACTICE TEST PACK COMPLETE SOLUTIONS
VERIFIED INSIGHTS


◉ enterokinase
Answer: activates trypsinogen; trypsin activates chymotrypsin,
procolipase, procarboxypeptidase, and proelastase


◉ arsenic
Answer: pyruvate dehydrogenase ib; smell of garlic


◉ Which GLUT is insulin-dependent?
Answer: GLUT4; found in muscle & adipose


◉ What is the role of F2,6BP?
Answer: role player for insulin; increases glycolysis for FA synth and
glycogen synthesis


◉ What is significant about glucokinase?
Answer: K_m is above fasting concentration, V_max is very high

, ◉ What promotes lactate buildup?
Answer: ^ NADH/NAD+


◉ Where does lactate build up?
Answer: eyes, testes, RBC's


◉ What is the rate-limiting step of glycolysis?
Answer: PFK, allosterically activated by F2,6BP


◉ Def in pyr kinase leads to...
Answer: 2,3BPG, G6P elevation due to ^ PEP


◉ What steroid can be used to treat beta-blocker overdose?
Answer: glucagon


◉ Which form of aldolase is liver-specific?
Answer: B


◉ triose phosphate isomerase
Answer: G3P <-> DHAP; DHAP - component of glycerol phosphate
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