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CBNS 120 FINAL QUESTIONS WITH VERIFIED ANSWERS

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CBNS 120 FINAL QUESTIONS WITH VERIFIED ANSWERS

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CBNS 120 FINAL QUESTIONS WITH VERIFIED
ANSWERS


Facilitation is a form of "short term synaptic plasticity" that leads to: - Answers -
progressive increase in EPP amplitude

Why does facilitation occur? - Answers - Residual calcium in the nerve terminal

What does synaptic depression result from? - Answers - Depletion of the readily
releasable store of synaptic vesicles

What does synaptic depression lead to? - Answers - Reduction in EPP amplitude

What is short term increase in EPP amplitude? - Answers - Facilitation

What is short term decrease in EPP amplitude? - Answers - Synaptic depression

What is long term increase in EPSP amplitude? - Answers - LTP

What is long term decrease in EPSP amplitude? - Answers - LTD

What is essential for induction of LTP1: - Answers - NMDA receptors and ryanodine
receptors

What does the induction of LTP3 require? - Answers - phosphorylation of CREB and
voltage gated calcium channels

synaptic depression may result from: - Answers - ca/calmodulin binding to the IM and
CBD motifs of the calcium channel

Induction of hippocampal LTD involved: - Answers - -activation of phosphatases
-prolonged low level increase of calcium in the postsynaptic cell
-reduction of postsynaptic AMPA receptor density

What are the critical components of cerebellar LTD? - Answers - metabotropic
glutamate receptors

In Aplysia, long term sensitisation: - Answers - -involves new gene expression
-depends on activation of CREB
-involves formation of new synapses

Inhibitors of CAMKII: - Answers - block LTP1

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