1|Page
ADVANCED PHARMACOLOGY FINAL EXAM (UTA)
EXAMINATION COMPLETE VERIFIED QUESTIONS
AND DETAILED SOLUTIONS LATEST UPDATE THIS
YEAR JUST RELEASED
Spironoaldactone (Aldactone) has what mechanism of
action (MOA)? - Answer-Aldosterone antagonist
Heparin exerts its therapeutic action by what? - Answer-
Upregulating the activity of one of the body's natural
anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug
is administered during an anaphylactic reaction. - Answer-
Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications? - Answer-
Photo-therapy and topical corticosteroids
What is the first choice of drug therapy for the majority of
patients with uncomplicated stage I hypertension? -
Answer-Thiazide diuretics
,2|Page
What is the effect of cardiac glycosides? - Answer-Digitalis
glycosides have a negative chronotropic effect on the
cardiac muscle cells.
Amenorrhea is the most common side effect of which birth
control medication? - Answer-Medroxyprogesterone
(Depo-Provera)
What is an anti-hypertensive agent which competes with
epinephrine for available beta-receptor sites? - Answer-
Atenolol (Tenormin)
What type of action does nitrates have on the body? -
Answer-Reduction in systemic venous tone.
What is the recommended level of low-density lipoprotein
cholesterol (LDL) for patients with known coronary artery
disease? - Answer-100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? -
Answer-Depressing phase 4 depolarization and
lengthening phases 1 and 2 repolarization.
,3|Page
Which drug therapy should be used to lower the serum
concentration of thyroid hormones and re-establish
eumetabolic state in a patient with Graves' disease? -
Answer-Anti-thyroid drugs.
Which type of diuretic would be used for a stage I
hypertension in a patient with renal insufficiency? -
Answer-Loop diuretic.
What drug should be considered as first-line therapy for a
client with hypertension and heart failure? - Answer-
Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment
during pregnancy? - Answer-Methyldopa (Aldomet)
What drug will reduce afterload because it is an alpha-
adrenergic blocker? - Answer-Prazosin (Minipress)
What is an expected effect of the use of a beta-adrenergic
blocker to control angina? - Answer-Reduced force of
cardiac contraction.
, 4|Page
What side effect should be monitored closely in the elderly
when taking Metformin (Glucophage) for type 2 diabetes?
- Answer-Lactic acidosis.
What is the primary role of cytochrome p-450 in the liver? -
Answer-Deactivate and detoxify medications and other
substances.
What is a component of Vitamin K-dependent clotting
factors? - Answer-Prothrombin
Why are nitrate-free periods every 24 hours necessary for
the patient on nitroglycerin therapy? - Answer-To inhibit
the development of tolerance
What does a low level of thyroid-stimulating hormone
indicate? - Answer-Hyperthroidism
What would be the best option to treat a newly diagnosed
patient with a low TSH level with? - Answer-Propanolol
(Inderal)
How are IV morphine and nitroglycerin beneficial in acute
heart failure? - Answer-Decrease preload.
ADVANCED PHARMACOLOGY FINAL EXAM (UTA)
EXAMINATION COMPLETE VERIFIED QUESTIONS
AND DETAILED SOLUTIONS LATEST UPDATE THIS
YEAR JUST RELEASED
Spironoaldactone (Aldactone) has what mechanism of
action (MOA)? - Answer-Aldosterone antagonist
Heparin exerts its therapeutic action by what? - Answer-
Upregulating the activity of one of the body's natural
anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug
is administered during an anaphylactic reaction. - Answer-
Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications? - Answer-
Photo-therapy and topical corticosteroids
What is the first choice of drug therapy for the majority of
patients with uncomplicated stage I hypertension? -
Answer-Thiazide diuretics
,2|Page
What is the effect of cardiac glycosides? - Answer-Digitalis
glycosides have a negative chronotropic effect on the
cardiac muscle cells.
Amenorrhea is the most common side effect of which birth
control medication? - Answer-Medroxyprogesterone
(Depo-Provera)
What is an anti-hypertensive agent which competes with
epinephrine for available beta-receptor sites? - Answer-
Atenolol (Tenormin)
What type of action does nitrates have on the body? -
Answer-Reduction in systemic venous tone.
What is the recommended level of low-density lipoprotein
cholesterol (LDL) for patients with known coronary artery
disease? - Answer-100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? -
Answer-Depressing phase 4 depolarization and
lengthening phases 1 and 2 repolarization.
,3|Page
Which drug therapy should be used to lower the serum
concentration of thyroid hormones and re-establish
eumetabolic state in a patient with Graves' disease? -
Answer-Anti-thyroid drugs.
Which type of diuretic would be used for a stage I
hypertension in a patient with renal insufficiency? -
Answer-Loop diuretic.
What drug should be considered as first-line therapy for a
client with hypertension and heart failure? - Answer-
Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment
during pregnancy? - Answer-Methyldopa (Aldomet)
What drug will reduce afterload because it is an alpha-
adrenergic blocker? - Answer-Prazosin (Minipress)
What is an expected effect of the use of a beta-adrenergic
blocker to control angina? - Answer-Reduced force of
cardiac contraction.
, 4|Page
What side effect should be monitored closely in the elderly
when taking Metformin (Glucophage) for type 2 diabetes?
- Answer-Lactic acidosis.
What is the primary role of cytochrome p-450 in the liver? -
Answer-Deactivate and detoxify medications and other
substances.
What is a component of Vitamin K-dependent clotting
factors? - Answer-Prothrombin
Why are nitrate-free periods every 24 hours necessary for
the patient on nitroglycerin therapy? - Answer-To inhibit
the development of tolerance
What does a low level of thyroid-stimulating hormone
indicate? - Answer-Hyperthroidism
What would be the best option to treat a newly diagnosed
patient with a low TSH level with? - Answer-Propanolol
(Inderal)
How are IV morphine and nitroglycerin beneficial in acute
heart failure? - Answer-Decrease preload.
