WGU D116 PRE-ASSESSMENT (PRE-A) QUESTIONS & ANSWERS 2026-2027 EXAM
P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
WGU D116 Pre-Assessment
(Pre-A) Questions &
Answers 2026-2027
Verified Answers Exam Ready With Rationales
60 QUESTIONS
DOCUMENT OVERVIEW
This document provides 60 pre-assessment questions with their correct answers, covering advanced
practice nursing scenarios. It is suitable for students to study and review key concepts in preparation for
certification exams. The material offers a direct way to familiarize oneself with question formats and
essential knowledge.
CONTENTS
01 Respiratory & Allergy Q1–Q6
02 Pain Management Q7–Q14
03 Cardiovascular Conditions Q15–Q21
04 Pharmacology & Patient Education Q22–Q41
05 Neurology & Mental Health Q42–Q45
Page 1
, 06 Endocrine Disorders Q46–Q53
07 Gastrointestinal & Renal Q54–Q60
E XA M Q U EST I O N S
Q1 QUESTION 1 OF 60
How will these drug interactions affect this patient?
An elderly patient with a history of asthma and hypertension presents to the emergency department
complaining of chest pain and shortness of breath. The advanced practice registered nurse (APRN) reviews
the patient's current medications and notes that the patient is taking propranolol and inhaled albuterol.
CORRECT ANSWER
Propranolol can decrease albuterol's therapeutic effect.
Q2 QUESTION 2 OF 60
A 35-year-old mother who is currently breastfeeding her four-month-old baby comes to a clinic for an
evaluation of a sinus infection. The advanced practice registered nurse needs to prescribe medication that
does not pass across the membrane into the breast milk.
CORRECT ANSWER
Lipid-soluble
Q3 QUESTION 3 OF 60
A patient presents to a clinic to follow up on allergic rhinitis. The patient has been taking cetirizine 10 mg/d
with decreased sneezing and itchiness of nose but reports no improvement in nasal stuffiness. An advanced
practice registered nurse (APRN) prescribes phenylephrine nasal spray twice a day for three days to treat
nasal congestion.
Which adverse effect is associated with prolonged use of phenylephrine nasal spray?
CORRECT ANSWER
Rebound congestion
Page 2
, Q4 QUESTION 4 OF 60
A patient with chronic obstructive pulmonary disease (COPD) has returned to a clinic for a follow-up
appointment. The advanced practice registered nurse (APRN) noticed that the patient has been taking
prednisone for a long period of time.
Which lab abnormality is an indicator of the adverse effect associated with prolonged use of this medication?
CORRECT ANSWER
Hyperglycemia
Q5 QUESTION 5 OF 60
A 75-year-old patient comes to an emergency room after eating shellfish. He presents with shortness of
breath, swollen eyes, and hives. The patient was given a dose of epinephrine intravenously and is stable
enough to discharge.
Which other medication should the patient be placed on to prevent a second reaction?
CORRECT ANSWER
Cetirizine
Q6 QUESTION 6 OF 60
An adult patient presents to a clinic complaining of nasal congestion with sneezing, itching, and rhinorrhea.
The patient reports to an advanced practice registered nurse (APRN) that cetirizine 10 mg is taken once daily,
but the nasal congestion continues.
Which medication should the APRN consider adding to this regimen?
CORRECT ANSWER
Fluticasone
Q7 QUESTION 7 OF 60
A 42-year-old patient suffering from pain due to cancer comes to a clinic and visits with the advanced
practice registered nurse (APRN). The APRN previously had prescribed morphine to treat the pain. The
patient is concerned because her bowel movements have become irregular and asks the APRN why she is
Page 3
P R O F E S S I O N A L P R A C T I C E M AT E R I A L S
WGU D116 Pre-Assessment
(Pre-A) Questions &
Answers 2026-2027
Verified Answers Exam Ready With Rationales
60 QUESTIONS
DOCUMENT OVERVIEW
This document provides 60 pre-assessment questions with their correct answers, covering advanced
practice nursing scenarios. It is suitable for students to study and review key concepts in preparation for
certification exams. The material offers a direct way to familiarize oneself with question formats and
essential knowledge.
CONTENTS
01 Respiratory & Allergy Q1–Q6
02 Pain Management Q7–Q14
03 Cardiovascular Conditions Q15–Q21
04 Pharmacology & Patient Education Q22–Q41
05 Neurology & Mental Health Q42–Q45
Page 1
, 06 Endocrine Disorders Q46–Q53
07 Gastrointestinal & Renal Q54–Q60
E XA M Q U EST I O N S
Q1 QUESTION 1 OF 60
How will these drug interactions affect this patient?
An elderly patient with a history of asthma and hypertension presents to the emergency department
complaining of chest pain and shortness of breath. The advanced practice registered nurse (APRN) reviews
the patient's current medications and notes that the patient is taking propranolol and inhaled albuterol.
CORRECT ANSWER
Propranolol can decrease albuterol's therapeutic effect.
Q2 QUESTION 2 OF 60
A 35-year-old mother who is currently breastfeeding her four-month-old baby comes to a clinic for an
evaluation of a sinus infection. The advanced practice registered nurse needs to prescribe medication that
does not pass across the membrane into the breast milk.
CORRECT ANSWER
Lipid-soluble
Q3 QUESTION 3 OF 60
A patient presents to a clinic to follow up on allergic rhinitis. The patient has been taking cetirizine 10 mg/d
with decreased sneezing and itchiness of nose but reports no improvement in nasal stuffiness. An advanced
practice registered nurse (APRN) prescribes phenylephrine nasal spray twice a day for three days to treat
nasal congestion.
Which adverse effect is associated with prolonged use of phenylephrine nasal spray?
CORRECT ANSWER
Rebound congestion
Page 2
, Q4 QUESTION 4 OF 60
A patient with chronic obstructive pulmonary disease (COPD) has returned to a clinic for a follow-up
appointment. The advanced practice registered nurse (APRN) noticed that the patient has been taking
prednisone for a long period of time.
Which lab abnormality is an indicator of the adverse effect associated with prolonged use of this medication?
CORRECT ANSWER
Hyperglycemia
Q5 QUESTION 5 OF 60
A 75-year-old patient comes to an emergency room after eating shellfish. He presents with shortness of
breath, swollen eyes, and hives. The patient was given a dose of epinephrine intravenously and is stable
enough to discharge.
Which other medication should the patient be placed on to prevent a second reaction?
CORRECT ANSWER
Cetirizine
Q6 QUESTION 6 OF 60
An adult patient presents to a clinic complaining of nasal congestion with sneezing, itching, and rhinorrhea.
The patient reports to an advanced practice registered nurse (APRN) that cetirizine 10 mg is taken once daily,
but the nasal congestion continues.
Which medication should the APRN consider adding to this regimen?
CORRECT ANSWER
Fluticasone
Q7 QUESTION 7 OF 60
A 42-year-old patient suffering from pain due to cancer comes to a clinic and visits with the advanced
practice registered nurse (APRN). The APRN previously had prescribed morphine to treat the pain. The
patient is concerned because her bowel movements have become irregular and asks the APRN why she is
Page 3
