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ATI Medical-Surgical Respiratory Practice Exam 2026 | 100 Questions & Answers with Detailed Rationales | Complete Exam Prep & Study Guide

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Prepare for the ATI Medical-Surgical Respiratory Practice Exam 2026 with a comprehensive 100-question study resource featuring correct answers and detailed rationales. This practice exam helps nursing students review respiratory disorders, assessment findings, oxygen therapy, medications, nursing interventions, patient education, and clinical judgment. Topics covered include: Respiratory anatomy and physiology Oxygenation and gas exchange Asthma Chronic obstructive pulmonary disease (COPD) Pneumonia Tuberculosis Pulmonary embolism Pneumothorax Pleural effusion Acute respiratory distress syndrome (ARDS) Respiratory failure Lung cancer Mechanical ventilation Tracheostomy care Chest tubes Oxygen therapy Suctioning Pulse oximetry and ABG interpretation Respiratory medications Infection prevention Patient education and nursing interventions Each question includes the correct answer and detailed rationale to reinforce important concepts and strengthen clinical reasoning. Ideal for ATI Medical-Surgical Nursing preparation, respiratory nursing exams, nursing school tests, clinical preparation, practice testing, and comprehensive review.

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_________________________________
__ATI Medical-Surgical Respiratory
Practice Exam 2026 | 100 Questions &
Answers with Detailed Rationales |
Complete Exam Prep & Study Guide

1. A nurse is assessing a client who has chronic obstructive pulmonary disease
(COPD). Which finding should the nurse expect?

A. Barrel-shaped chest
B. Bradycardia
C. Decreased anterior-posterior chest diameter
D. Pink frothy sputum

Answer: Barrel-shaped chest

Rationale: A barrel-shaped chest results from chronic air trapping and
hyperinflation of the lungs, which is common in COPD.

2. A nurse is caring for a client experiencing an acute asthma attack. Which
medication should the nurse expect to administer for rapid relief?

A. Fluticasone
B. Montelukast
C. Albuterol
D. Salmeterol

Answer: Albuterol

,Rationale: Albuterol is a short-acting beta2-adrenergic agonist that rapidly
relaxes bronchial smooth muscle and provides quick relief during an acute
asthma exacerbation.

3. A client with COPD is receiving oxygen therapy. Which oxygen prescription
should the nurse question?

A. Oxygen at 1 L/min via nasal cannula
B. Oxygen at 2 L/min via nasal cannula
C. Oxygen at 10 L/min via nonrebreather mask
D. Oxygen adjusted to maintain the prescribed saturation range

Answer: Oxygen at 10 L/min via nonrebreather mask

Rationale: Clients with chronic CO₂ retention can be sensitive to excessive
oxygen administration. Oxygen should be carefully titrated according to the
prescribed target saturation and clinical condition.

4. A nurse is teaching a client how to use an incentive spirometer after
surgery. Which instruction is appropriate?

A. Exhale forcefully into the mouthpiece
B. Inhale slowly and deeply through the mouthpiece
C. Use the device once every 8 hr
D. Cough immediately before each inhalation

Answer: Inhale slowly and deeply through the mouthpiece

Rationale: Slow, sustained inhalation through an incentive spirometer promotes
alveolar expansion and helps prevent postoperative atelectasis.

5. A client with pneumonia has thick respiratory secretions. Which
intervention should the nurse include?

A. Restrict oral fluids
B. Encourage adequate fluid intake if not contraindicated
C. Maintain strict bed rest
D. Limit coughing

,Answer: Encourage adequate fluid intake if not contraindicated

Rationale: Adequate hydration helps thin respiratory secretions, making them
easier to expectorate.

6. A nurse is assessing a client with pneumonia. Which finding should the
nurse expect?

A. Crackles
B. Absent bowel sounds
C. Hyperactive reflexes
D. Peripheral edema only

Answer: Crackles

Rationale: Pneumonia can cause alveolar fluid and inflammatory exudate,
resulting in crackles on auscultation.

7. A client with pulmonary tuberculosis is admitted to the hospital. Which
type of precautions should the nurse initiate?

A. Contact
B. Droplet
C. Airborne
D. Protective

Answer: Airborne

Rationale: Pulmonary tuberculosis is transmitted through airborne particles. The
client should be placed in an airborne infection isolation room, and appropriate
respiratory protection should be used.

8. Which personal protective equipment should a nurse wear when entering
the room of a client with suspected active pulmonary tuberculosis?

A. Surgical mask
B. N95 respirator

, C. Face shield only
D. Sterile gloves only

Answer: N95 respirator

Rationale: An N95 respirator or equivalent respiratory protection is required for
healthcare workers caring for clients with suspected or confirmed airborne
tuberculosis.

9. A client with a pneumothorax has a chest tube connected to a drainage
system. Which finding requires immediate attention?

A. Tidaling in the water-seal chamber
B. Small amount of drainage
C. Continuous bubbling in the water-seal chamber
D. Mild discomfort at the insertion site

Answer: Continuous bubbling in the water-seal chamber

Rationale: Continuous bubbling in the water-seal chamber can indicate an air
leak in the system and requires assessment.

10.A nurse is caring for a client with a chest tube. Which action is appropriate?

A. Clamp the tube routinely
B. Keep the drainage system below the client's chest
C. Strip the tubing every hour
D. Disconnect the system during ambulation

Answer: Keep the drainage system below the client's chest

Rationale: Keeping the drainage system below chest level promotes gravity
drainage and helps prevent fluid from flowing back into the pleural space.

11.A nurse is assessing a client with a pulmonary embolism. Which finding is
most likely?

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