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ATI Dosage Calculation Practice Exam 2026 | 100 Questions & Answers with Detailed Rationales | Complete Exam Prep & Study Guide

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Prepare for the ATI Dosage Calculation Practice Exam 2026 with a comprehensive 100-question study resource featuring answers and detailed rationales. This practice exam is designed to help nursing students strengthen medication math skills, improve calculation accuracy, and build confidence for ATI assessments and nursing school exams. Topics covered include: Basic dosage calculations Metric and household conversions Medication dose calculations Oral and liquid medications Tablets and capsules Injectable medications IV flow rates IV medication calculations Infusion rates Weight-based dosing Pediatric dosage calculations Reconstitution of medications Dimensional analysis Ratio and proportion Safe medication administration Rounding and calculation rules Each question includes the correct answer and detailed rationale to help reinforce calculation methods and explain the reasoning behind each solution. Ideal for ATI dosage calculation preparation, nursing school exams, medication math practice, clinical preparation, and comprehensive review.

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ATI Dosage Calculation Practice Exam
2026 | 100 Questions & Answers with
Detailed Rationales | Complete Exam
Prep & Study Guide

1. A nurse is preparing to administer acetaminophen 650 mg PO. Available
tablets contain 325 mg each. How many tablets should the nurse
administer?

Answer: 2 tablets

Rationale: 650 mg ÷ 325 mg/tablet = 2 tablets.

2. A prescription reads amoxicillin 500 mg PO. The available medication is 250
mg/5 mL. How many mL should the nurse administer?

Answer: 10 mL

Rationale: (500 mg ÷ 250 mg) × 5 mL = 10 mL.

3. A client is prescribed furosemide 40 mg PO. Available tablets are 20 mg
each. How many tablets should the nurse administer?

Answer: 2 tablets

Rationale: 40 mg ÷ 20 mg/tablet = 2 tablets.

, 4. A prescription is for levothyroxine 0.075 mg PO. Available tablets are 25
mcg each. How many tablets should the nurse administer?

Answer: 3 tablets

Rationale: 0.075 mg = 75 mcg. 75 mcg ÷ 25 mcg/tablet = 3 tablets.

5. A client is prescribed digoxin 0.125 mg PO. Available tablets contain 0.25
mg. How many tablets should the nurse administer?

Answer: 0.5 tablet

Rationale: 0.125 mg ÷ 0.25 mg/tablet = 0.5 tablet.

6. A nurse needs to administer ibuprofen 400 mg PO. Available tablets contain
200 mg each. How many tablets are required?

Answer: 2 tablets

Rationale: 400 mg ÷ 200 mg/tablet = 2 tablets.

7. A prescription is for prednisone 15 mg PO. Available tablets contain 5 mg
each. How many tablets should the nurse administer?

Answer: 3 tablets

Rationale: 15 mg ÷ 5 mg/tablet = 3 tablets.

8. A child is prescribed cephalexin 375 mg PO. The medication available is 250
mg/5 mL. How many mL should be administered?

Answer: 7.5 mL

Rationale: (375 mg ÷ 250 mg) × 5 mL = 7.5 mL.

9. A prescription reads metronidazole 500 mg PO. Available tablets contain
250 mg. How many tablets should be administered?

Answer: 2 tablets

Rationale: 500 mg ÷ 250 mg/tablet = 2 tablets.

, 10.A client is prescribed potassium chloride 20 mEq PO. Available tablets
contain 10 mEq each. How many tablets should the nurse administer?

Answer: 2 tablets

Rationale: 20 mEq ÷ 10 mEq/tablet = 2 tablets.

11.A nurse must administer morphine 6 mg IV. The vial contains 10 mg/mL.
How many mL should be administered?

Answer: 0.6 mL

Rationale: 6 mg ÷ 10 mg/mL = 0.6 mL.

12.A prescription is for ondansetron 4 mg IV. Available medication is 2 mg/mL.
How many mL should the nurse administer?

Answer: 2 mL

Rationale: 4 mg ÷ 2 mg/mL = 2 mL.

13.A client weighs 154 lb. What is the client's weight in kilograms?

Answer: 70 kg

Rationale: 154 lb ÷ 2.2 lb/kg = 70 kg.

14.A child weighs 44 lb. What is the child's weight in kilograms?

Answer: 20 kg

Rationale: 44 lb ÷ 2.2 lb/kg = 20 kg.

15.A prescription is for 10 mg/kg/day of a medication for a child weighing 22
kg. The medication is prescribed once daily. How many mg should the child
receive per dose?

Answer: 220 mg

Rationale: 10 mg × 22 kg = 220 mg/day. Since it is given once daily, the dose is
220 mg.

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