ATI RN Comprehensive
Predictor Examination
Level 4 | Proctored | 2026 Edition
120 Multiple-Choice Questions
With Rationales and Correct Answers
Patient-Centered Care | Evidence-Based Practice | Informatics & Technology
Safety & Infection Control | Health Promotion | Pharmacology | Physiological Integrity
Assessment Technologies Institute | Practice Examination | For Educational Use Only
,ATI RN Comprehensive Predictor Exam | Level 4 | 2026 Practice Examination
ATI RN Comprehensive Predictor Examination
Level 4 | Proctored | 2026 Edition
120 Multiple-Choice Questions with Rationales
This practice examination consists of 120 multiple-choice questions designed to assess your nursing
knowledge across all major content areas tested on the ATI RN Comprehensive Predictor Exam. Each
question includes the correct answer and a detailed rationale to support your learning.
Content Areas Covered:
• Patient-Centered Care (Comfort, End-of-Life, Diversity, Communication)
• Evidence-Based Practice and Quality Improvement
• Informatics and Technology
• Safety and Infection Control
• Health Promotion and Maintenance
• Pharmacology
• Physiological Integrity (Basic Care, Reduction of Risk, Physiological Adaptation)
Instructions: Read each question carefully. Select the best answer from the four options provided. The
correct answer and rationale are included below each question for self-study purposes.
Quick Reference: Answer Key
Q Ans Q Ans Q Ans Q Ans
1 B 2 B 3 B 4 C
5 B 6 D 7 C 8 B
9 B 10 A 11 B 12 B
13 B 14 B 15 B 16 C
17 C 18 A 19 C 20 B
21 B 22 C 23 B 24 B
25 C 26 C 27 B 28 C
29 B 30 A 31 D 32 B
33 B 34 A 35 A 36 B
37 B 38 B 39 C 40 A
41 B 42 B 43 B 44 B
Page 2
,ATI RN Comprehensive Predictor Exam | Level 4 | 2026 Practice Examination
45 B 46 B 47 C 48 B
49 B 50 A 51 B 52 C
53 B 54 B 55 B 56 B
57 B 58 C 59 A 60 C
61 B 62 B 63 B 64 A
65 B 66 C 67 C 68 C
69 B 70 D 71 B 72 B
73 B 74 B 75 B 76 B
77 B 78 B 79 B 80 B
81 B 82 B 83 B 84 B
85 B 86 B 87 B 88 B
89 A 90 B 91 B 92 B
93 B 94 B 95 B 96 B
97 A 98 B 99 B 100 B
101 B 102 B 103 B 104 D
105 B 106 B 107 B 108 B
109 A 110 A 111 C 112 B
113 B 114 B 115 B 116 A
117 B 118 B 119 B 120 B
Page 3
, ATI RN Comprehensive Predictor Exam | Level 4 | 2026 Practice Examination
Section 1: Patient-Centered Care (Comfort, End-of-Life, Diversity,
Communication)
Question 1
A nurse is caring for a patient with terminal cancer who has a prognosis of fewer than 6 months. The
patient reports worsening pain at a level of 8 on a 0-10 scale despite current analgesic therapy. Which of
the following is the priority nursing action?
A. Administer a non-opioid analgesic such as acetaminophen
✓ B. Consult the interdisciplinary palliative care team for pain management optimization (Correct
Answer)
C. Encourage the patient to use guided imagery and relaxation techniques
D. Document the pain assessment and reassess in 4 hours
Rationale:
The priority action is to consult the palliative care team because the patient's pain is uncontrolled despite current
therapy and the patient has a terminal prognosis with fewer than 6 months to live. Palliative care uses an
interdisciplinary approach to optimize symptom management through pharmacological and non-pharmacological
interventions. Acetaminophen alone is insufficient for severe pain rated at 8/10. While relaxation techniques are
beneficial adjuvants, they are not the priority when pain is this severe. Simply documenting and waiting 4 hours
delays necessary pain relief.
Question 2
A nurse is providing end-of-life care for a patient who is actively dying. The patient's family asks the nurse,
"What can we expect as death approaches?" Which of the following is the most appropriate nursing
response?
A. "Your loved one will likely become more alert and talkative in the final hours."
✓ B. "You may notice changes in breathing patterns, decreased urine output, and coolness in the
extremities." (Correct Answer)
C. "Death is unpredictable, so there is really no way to know what will happen."
D. "The most important thing is to keep talking to your loved one so they can hear you."
Rationale:
This response provides accurate, honest information about expected physiological changes at the end of life,
including Cheyne-Stokes respirations, oliguria, and peripheral cyanosis and mottling. Providing the family with
anticipatory guidance reduces fear and helps them understand the dying process. Option A is incorrect because
increasing alertness is not expected; rather, patients typically experience decreasing consciousness. Option C is
non-therapeutic because it dismisses the family's need for information. While option D is supportive, it does not
answer the family's question about what to expect.
Question 3
A nurse is assessing a patient's pain using the WHO Pain Ladder approach. The patient reports persistent
moderate pain (5/10) that is not adequately controlled with acetaminophen. Which of the following is the
Page 4
Predictor Examination
Level 4 | Proctored | 2026 Edition
120 Multiple-Choice Questions
With Rationales and Correct Answers
Patient-Centered Care | Evidence-Based Practice | Informatics & Technology
Safety & Infection Control | Health Promotion | Pharmacology | Physiological Integrity
Assessment Technologies Institute | Practice Examination | For Educational Use Only
,ATI RN Comprehensive Predictor Exam | Level 4 | 2026 Practice Examination
ATI RN Comprehensive Predictor Examination
Level 4 | Proctored | 2026 Edition
120 Multiple-Choice Questions with Rationales
This practice examination consists of 120 multiple-choice questions designed to assess your nursing
knowledge across all major content areas tested on the ATI RN Comprehensive Predictor Exam. Each
question includes the correct answer and a detailed rationale to support your learning.
Content Areas Covered:
• Patient-Centered Care (Comfort, End-of-Life, Diversity, Communication)
• Evidence-Based Practice and Quality Improvement
• Informatics and Technology
• Safety and Infection Control
• Health Promotion and Maintenance
• Pharmacology
• Physiological Integrity (Basic Care, Reduction of Risk, Physiological Adaptation)
Instructions: Read each question carefully. Select the best answer from the four options provided. The
correct answer and rationale are included below each question for self-study purposes.
Quick Reference: Answer Key
Q Ans Q Ans Q Ans Q Ans
1 B 2 B 3 B 4 C
5 B 6 D 7 C 8 B
9 B 10 A 11 B 12 B
13 B 14 B 15 B 16 C
17 C 18 A 19 C 20 B
21 B 22 C 23 B 24 B
25 C 26 C 27 B 28 C
29 B 30 A 31 D 32 B
33 B 34 A 35 A 36 B
37 B 38 B 39 C 40 A
41 B 42 B 43 B 44 B
Page 2
,ATI RN Comprehensive Predictor Exam | Level 4 | 2026 Practice Examination
45 B 46 B 47 C 48 B
49 B 50 A 51 B 52 C
53 B 54 B 55 B 56 B
57 B 58 C 59 A 60 C
61 B 62 B 63 B 64 A
65 B 66 C 67 C 68 C
69 B 70 D 71 B 72 B
73 B 74 B 75 B 76 B
77 B 78 B 79 B 80 B
81 B 82 B 83 B 84 B
85 B 86 B 87 B 88 B
89 A 90 B 91 B 92 B
93 B 94 B 95 B 96 B
97 A 98 B 99 B 100 B
101 B 102 B 103 B 104 D
105 B 106 B 107 B 108 B
109 A 110 A 111 C 112 B
113 B 114 B 115 B 116 A
117 B 118 B 119 B 120 B
Page 3
, ATI RN Comprehensive Predictor Exam | Level 4 | 2026 Practice Examination
Section 1: Patient-Centered Care (Comfort, End-of-Life, Diversity,
Communication)
Question 1
A nurse is caring for a patient with terminal cancer who has a prognosis of fewer than 6 months. The
patient reports worsening pain at a level of 8 on a 0-10 scale despite current analgesic therapy. Which of
the following is the priority nursing action?
A. Administer a non-opioid analgesic such as acetaminophen
✓ B. Consult the interdisciplinary palliative care team for pain management optimization (Correct
Answer)
C. Encourage the patient to use guided imagery and relaxation techniques
D. Document the pain assessment and reassess in 4 hours
Rationale:
The priority action is to consult the palliative care team because the patient's pain is uncontrolled despite current
therapy and the patient has a terminal prognosis with fewer than 6 months to live. Palliative care uses an
interdisciplinary approach to optimize symptom management through pharmacological and non-pharmacological
interventions. Acetaminophen alone is insufficient for severe pain rated at 8/10. While relaxation techniques are
beneficial adjuvants, they are not the priority when pain is this severe. Simply documenting and waiting 4 hours
delays necessary pain relief.
Question 2
A nurse is providing end-of-life care for a patient who is actively dying. The patient's family asks the nurse,
"What can we expect as death approaches?" Which of the following is the most appropriate nursing
response?
A. "Your loved one will likely become more alert and talkative in the final hours."
✓ B. "You may notice changes in breathing patterns, decreased urine output, and coolness in the
extremities." (Correct Answer)
C. "Death is unpredictable, so there is really no way to know what will happen."
D. "The most important thing is to keep talking to your loved one so they can hear you."
Rationale:
This response provides accurate, honest information about expected physiological changes at the end of life,
including Cheyne-Stokes respirations, oliguria, and peripheral cyanosis and mottling. Providing the family with
anticipatory guidance reduces fear and helps them understand the dying process. Option A is incorrect because
increasing alertness is not expected; rather, patients typically experience decreasing consciousness. Option C is
non-therapeutic because it dismisses the family's need for information. While option D is supportive, it does not
answer the family's question about what to expect.
Question 3
A nurse is assessing a patient's pain using the WHO Pain Ladder approach. The patient reports persistent
moderate pain (5/10) that is not adequately controlled with acetaminophen. Which of the following is the
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