NRl 567/l NR567l Midterml Exam:l
Advancedl Pharmacologyl forl thel
AGACNPl Reviewl Guidel (Latestl 2026/l
2027l Update)l |l Qsl &l As|l Gradel A|l
100%l Correctl (Verifiedl Answers)-l
Chamberlain
QUESTION
Whatl precautionsl shouldl bel takenl whenl usingl anestheticsl inl clientsl withl cardiacl
dysfunction?
Answer:
Usel cautiouslyl inl clientsl withl cardiacl dysfunction.
QUESTION
Whyl shouldl locall anestheticsl bel usedl cautiouslyl inl clientsl withl liverl disease?
Answer:
Duel tol hepaticl metabolism.
QUESTION
Whatl isl al criticall considerationl forl topicall formsl ofl locall anesthetics?
Answer:
Ensurel skinl isl intact,l asl brokenl skinl enhancesl thel riskl ofl systemicl absorption.
QUESTION
Whatl testl shouldl bel monitoredl duel tol thel hepaticl metabolisml ofl lidocaine?
,Answer:
Liverl functionl test.
QUESTION
Howl doesl addingl sodiuml bicarbonatel tol locall anestheticsl affectl pain?
Answer:
Itl increasesl thel pHl tol decreasel pain.
QUESTION
Whatl arel somel sidel effectsl ofl inhaledl anestheticsl likel Isoflurane?
Answer:
Respiratoryl depression,l hypotension,l malignantl hyperthermia,l GIl effectsl (N/V),l increasedl
ICP,l shivering,l hepaticl effectsl (increasel inl liverl enzymes),l andl arrhythmias.
QUESTION
Whatl isl thel mechanisml ofl actionl (MOA)l ofl Succinylcholine?
Answer:
Itl bindsl tol nicotinicl receptorsl atl thel neuromuscularl junction,l causingl depolarizationl andl
initiall musclel contraction,l leadingl tol sustainedl flaccidl musclel paralysis.
QUESTION
Whatl arel thel sidel effectsl ofl Succinylcholine?
Answer:
Hyperkalemia,l apnea,l increasedl pressurel inl thel body,l malignantl hyperthermia,l cardiacl
effectsl (bradycardial orl tachycardia),l andl myalgia.
QUESTION
Whatl monitoringl isl requiredl forl clientsl receivingl Succinylcholine?
,Answer:
Monitorl BMPl forl potassiuml levelsl andl cholinesterasel plasmal levelsl inl clientsl withl
suspectedl familiall pseudocholinesterasel deficiency.
QUESTION
Whatl isl thel typicall dosingl forl Succinylcholinel duringl intubation?
Answer:
1-2l mg/kg.
QUESTION
Whatl isl thel treatmentl forl malignantl hyperthermia?
Answer:
Dantrolene,l typicallyl 2.5l mg/kgl withl repeatedl dosesl ofl 1l mg/kgl untill symptomsl subside.
QUESTION
Whatl complicationsl canl arisel froml tracheall intubation?
Answer:
Hypoxia,l aspiration,l traumal tol teeth/vocall cords,l esophageall intubation,l hypotension,l andl
pneumothorax.
QUESTION
Whatl isl thel mechanisml ofl actionl ofl Propofol?
Answer:
Itl potentiatesl thel chloridel currentl mediatedl throughl thel GABAAl receptorl complex,l
leadingl tol CNSl depressionl andl rapidl onsetl anesthesia.
QUESTION
Whatl isl anl off-labell usel ofl Propofol?
, Answer:
Tol treatl refractoryl statusl epilepticus.
QUESTION
Whatl arel somel sidel effectsl associatedl withl Propofol?
Answer:
Respiratoryl depression,l hypotension,l painl atl thel injectionl site,l Propofoll infusionl
syndrome,l allergicl reactions,l infection,l bradycardia,l andl asystole.
QUESTION
Whatl precautionsl shouldl bel takenl whenl administeringl Propofol?
Answer:
Usel cautionl inl clientsl withl cardiacl disease,l hypovolemia,l orl impairedl lipidl metabolism.
QUESTION
Inl whichl patientsl isl Propofoll contraindicated?
Answer:
Patientsl withl allergyl tol Propofoll orl itsl componentsl (soybeanl oil,l eggl lecithin)l andl thosel
withl disordersl ofl fatl metabolism.
QUESTION
Whatl monitoringl isl necessaryl forl clientsl onl prolongedl infusionsl ofl Propofol?
Answer:
Monitorl renall functionl andl electrolytesl (BMP)l andl triglyceridesl duel tol lipidl content.
QUESTION
Whatl arel thel contraindicationsl forl Lidocainel withl epinephrine?
Advancedl Pharmacologyl forl thel
AGACNPl Reviewl Guidel (Latestl 2026/l
2027l Update)l |l Qsl &l As|l Gradel A|l
100%l Correctl (Verifiedl Answers)-l
Chamberlain
QUESTION
Whatl precautionsl shouldl bel takenl whenl usingl anestheticsl inl clientsl withl cardiacl
dysfunction?
Answer:
Usel cautiouslyl inl clientsl withl cardiacl dysfunction.
QUESTION
Whyl shouldl locall anestheticsl bel usedl cautiouslyl inl clientsl withl liverl disease?
Answer:
Duel tol hepaticl metabolism.
QUESTION
Whatl isl al criticall considerationl forl topicall formsl ofl locall anesthetics?
Answer:
Ensurel skinl isl intact,l asl brokenl skinl enhancesl thel riskl ofl systemicl absorption.
QUESTION
Whatl testl shouldl bel monitoredl duel tol thel hepaticl metabolisml ofl lidocaine?
,Answer:
Liverl functionl test.
QUESTION
Howl doesl addingl sodiuml bicarbonatel tol locall anestheticsl affectl pain?
Answer:
Itl increasesl thel pHl tol decreasel pain.
QUESTION
Whatl arel somel sidel effectsl ofl inhaledl anestheticsl likel Isoflurane?
Answer:
Respiratoryl depression,l hypotension,l malignantl hyperthermia,l GIl effectsl (N/V),l increasedl
ICP,l shivering,l hepaticl effectsl (increasel inl liverl enzymes),l andl arrhythmias.
QUESTION
Whatl isl thel mechanisml ofl actionl (MOA)l ofl Succinylcholine?
Answer:
Itl bindsl tol nicotinicl receptorsl atl thel neuromuscularl junction,l causingl depolarizationl andl
initiall musclel contraction,l leadingl tol sustainedl flaccidl musclel paralysis.
QUESTION
Whatl arel thel sidel effectsl ofl Succinylcholine?
Answer:
Hyperkalemia,l apnea,l increasedl pressurel inl thel body,l malignantl hyperthermia,l cardiacl
effectsl (bradycardial orl tachycardia),l andl myalgia.
QUESTION
Whatl monitoringl isl requiredl forl clientsl receivingl Succinylcholine?
,Answer:
Monitorl BMPl forl potassiuml levelsl andl cholinesterasel plasmal levelsl inl clientsl withl
suspectedl familiall pseudocholinesterasel deficiency.
QUESTION
Whatl isl thel typicall dosingl forl Succinylcholinel duringl intubation?
Answer:
1-2l mg/kg.
QUESTION
Whatl isl thel treatmentl forl malignantl hyperthermia?
Answer:
Dantrolene,l typicallyl 2.5l mg/kgl withl repeatedl dosesl ofl 1l mg/kgl untill symptomsl subside.
QUESTION
Whatl complicationsl canl arisel froml tracheall intubation?
Answer:
Hypoxia,l aspiration,l traumal tol teeth/vocall cords,l esophageall intubation,l hypotension,l andl
pneumothorax.
QUESTION
Whatl isl thel mechanisml ofl actionl ofl Propofol?
Answer:
Itl potentiatesl thel chloridel currentl mediatedl throughl thel GABAAl receptorl complex,l
leadingl tol CNSl depressionl andl rapidl onsetl anesthesia.
QUESTION
Whatl isl anl off-labell usel ofl Propofol?
, Answer:
Tol treatl refractoryl statusl epilepticus.
QUESTION
Whatl arel somel sidel effectsl associatedl withl Propofol?
Answer:
Respiratoryl depression,l hypotension,l painl atl thel injectionl site,l Propofoll infusionl
syndrome,l allergicl reactions,l infection,l bradycardia,l andl asystole.
QUESTION
Whatl precautionsl shouldl bel takenl whenl administeringl Propofol?
Answer:
Usel cautionl inl clientsl withl cardiacl disease,l hypovolemia,l orl impairedl lipidl metabolism.
QUESTION
Inl whichl patientsl isl Propofoll contraindicated?
Answer:
Patientsl withl allergyl tol Propofoll orl itsl componentsl (soybeanl oil,l eggl lecithin)l andl thosel
withl disordersl ofl fatl metabolism.
QUESTION
Whatl monitoringl isl necessaryl forl clientsl onl prolongedl infusionsl ofl Propofol?
Answer:
Monitorl renall functionl andl electrolytesl (BMP)l andl triglyceridesl duel tol lipidl content.
QUESTION
Whatl arel thel contraindicationsl forl Lidocainel withl epinephrine?
