QUESTIONS AND ANSWERS WITH VERIFIED
RATIONALES, 100% GUARANTEE PASS - WILKES
Graduate Nursing Comprehensive Practice Exam (Original)
Part 1: Health Promotion & Disease Prevention (Questions 1–15)
Table of Contents
Section Questions
Part 1 – Health Promotion & Disease Prevention 1–15
Part 2 – Cardiovascular Disorders 16–30
Part 3 – Respiratory Disorders 31–40
Part 4 – Endocrine Disorders 41–50
Part 5 – Gastrointestinal Disorders 51–60
Part 6 – Neurological Disorders 61–70
Part 7 – Women's Health 71–80
Part 8 – Pediatrics 81–90
Part 9 – Pharmacology & Clinical Decision-Making 91–100
Question 1
A 52-year-old woman presents for a routine wellness visit. She has hypertension that is well
controlled with medication and has no other significant medical history. Which screening test
should be recommended?
A. Annual chest CT scan
B. Routine mammography according to age-based guidelines
C. Colonoscopy every year
D. Echocardiogram every year
,Correct Answer: B. Routine mammography according to age-based guidelines
Rationale:
Routine mammography is recommended for women beginning at the appropriate age according
to current screening guidelines and individual risk factors. Annual chest CT is reserved for high-
risk smokers. Colonoscopy is generally performed at recommended intervals (often every 10
years for average-risk adults after a normal examination), not annually. Echocardiography is not
recommended as a screening test in asymptomatic patients.
Question 2
A patient has smoked one pack of cigarettes daily for 30 years and currently smokes. Which
screening is most appropriate?
A. Annual pulmonary function testing
B. Annual low-dose CT scan of the chest
C. Routine chest radiograph
D. PET scan every two years
Correct Answer: B. Annual low-dose CT scan of the chest
Rationale:
Eligible adults with a significant smoking history may benefit from annual low-dose CT
screening for lung cancer if they meet current screening criteria. Chest radiographs and
pulmonary function tests are not effective lung cancer screening tools, and PET scans are not
recommended for routine screening.
Question 3
Which intervention has the greatest impact on reducing cardiovascular disease risk?
A. Daily multivitamin
B. Smoking cessation
C. Vitamin D supplementation
D. Limiting dairy intake
Correct Answer: B. Smoking cessation
Rationale:
Smoking cessation significantly reduces the risk of myocardial infarction, stroke, peripheral
,arterial disease, and many cancers. Although nutrition is important, stopping tobacco use
provides one of the largest reductions in preventable cardiovascular risk.
Question 4
A 48-year-old patient has a blood pressure of 146/92 mm Hg during today's visit. What is the
most appropriate next step?
A. Diagnose hypertension immediately
B. Confirm elevated blood pressure with repeat measurements on separate occasions unless
hypertensive urgency or emergency is present
C. Begin two antihypertensive medications immediately
D. No additional evaluation is necessary
Correct Answer: B. Confirm elevated blood pressure with repeat measurements on
separate occasions unless hypertensive urgency or emergency is present
Rationale:
Hypertension should generally be confirmed with repeat office measurements or validated out-
of-office monitoring before establishing the diagnosis, unless the patient has markedly elevated
blood pressure with evidence of acute target-organ damage.
Question 5
Which vaccine is recommended annually for nearly all adults without contraindications?
A. Hepatitis A
B. Influenza
C. HPV
D. Meningococcal
Correct Answer: B. Influenza
Rationale:
Seasonal influenza vaccination is recommended annually for nearly everyone aged six months
and older who does not have a contraindication. Other vaccines are recommended based on age,
risk factors, or specific exposures.
, Question 6
A patient has obesity and prediabetes. Which intervention has the strongest evidence for
preventing progression to type 2 diabetes?
A. Daily vitamin C
B. Lifestyle modification emphasizing weight loss and regular physical activity
C. Routine insulin therapy
D. High-protein supplements only
Correct Answer: B. Lifestyle modification emphasizing weight loss and regular physical
activity
Rationale:
Lifestyle interventions that include dietary changes, weight reduction, and regular exercise are
highly effective in delaying or preventing progression from prediabetes to type 2 diabetes.
Question 7
A patient asks about primary prevention. Which example best represents primary prevention?
A. Colonoscopy
B. Mammography
C. Immunization
D. Cardiac rehabilitation
Correct Answer: C. Immunization
Rationale:
Primary prevention aims to prevent disease before it occurs. Vaccination is a classic example.
Colonoscopy and mammography are secondary prevention because they detect disease early.
Cardiac rehabilitation is tertiary prevention.
Question 8
Which lipid profile finding is considered a major risk factor for atherosclerotic cardiovascular
disease?
A. Elevated LDL cholesterol
B. Low triglycerides