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HCS 213 Exam 1 Questions With Verified Answers

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HCS 213 Exam 1 Questions With
Verified Answers


gap junctions - ANSWER link adjacent cells and are formed by connexins
movement of ions throygh gap junctions electrically couples the cells so that the
electrical signals in one cell are directly transmitted to the neighboring cell

gap junctions are in the hearrt and smooth muslce

connexins - ANSWER plasma membrane proteins that form structures called
connexins

connexons - ANSWER form channels that allow ions and small molecules to pass

connexons - ANSWER link adjacent cells (their cytosols)

communication via second messengers - ANSWER secretory cell releases a
messenger into the extracellular fluid and the messenger binds to the receptors
on the target cells triggering a response in the cell

ligands - ANSWER bind proteins reversibly

chemical messengers - ANSWER one cell release a chemical into the intersitial
fluid usually by a process called secretion and another cell called the target cell
that responds to the chemical messenger

receptors - ANSWER proteins on a target cell that recognize a chemical
messenger in sensory systems dectors of stimuli

signal transduction - ANSWER binding of chemical messenger to receptors
brings about a response in a target cell

,number of bound receptors depends on both the - ANSWER concentration of the
messenger in the intersitial fluid and concentration of receptors on the target
cells

enzymes - ANSWER increase in concentration of or substrate increases
chemical rxn rate

3 categories of chemical messengers - ANSWER 1. paracrine
2. neurotransmitters
3. hormones
PNH

paracrine - ANSWER secreted by one cell and diffuse to a nearby target cell

neurotransmitters - ANSWER secreted from neurons at functionally specialized
structures called synapses

hormones - ANSWER secreted by the endocrine cells into the intersitial fluid

paracrine - ANSWER communicates by simply diffusion

paracrine examples - ANSWER 1. growth factors
2. clotting factors
3. cytokines

mast cells secrete - ANSWER histamine
paracrine cell

autocrines - ANSWER subclass of paracrines tat act on the same cell that
ecretes them
the secretory cell is also the target cell

neurotransmitters - ANSWER chemicals released into interisital fluid by neurons

neurotransmitters are released from a portion of the neuron called - ANSWER
axon terminal

junction between axon terminal and target cell - ANSWER synapse

hormones - ANSWER chemical messengers released from endocrine cells or
glands into intersitial fluid were they diffuse into the blood and travel to target
cells
travels in the blood to its target cells

neurohormones - ANSWER special class of hormones released by
neurosecreotyr cells

, neurohoromone examples - ANSWER vasopressin, ADH

lipopilic (hydrophobic) - ANSWER lipid soluble and cross the plasmam
membrane

lipophobic (hydrophilic) - ANSWER water soluble and dissolve in plasma but do
not cross the membrane

5 classes of chemical messengers - ANSWER 1. amino acids
2. amines
3. peptides/proteins
4. steroids
5. eicosanoids

catecholamines - ANSWER catechol group (six carbon ring)
derived from the amino acid tyrosine
they include dopamine norepinephrine, and epinehphrine

serotonin - ANSWER amine neurotransmitter
derived from tryptophan

thyroid homrones - ANSWER tyrosine

paracrine - ANSWER histamine

eicosanoid messengers - ANSWER derivatives of arachidonic acid which is a 20
carbon fatty acid in plasmam membrane pospholipids and they readily cross the
plasmam mmembrane and re hydropobic

eicosanoids include the following: - ANSWER prostaglandins, leuotrienes,
thromboxanes

amino acid neurotransmitters are - ANSWER transported into vesicles where
they are stored until exocytosis

catecholamines - ANSWER dopamine is a precursor for norepinpeprhine which
in turn servers as a precursor for epinperine

after dopamine is synthesized it is - ANSWER transported into vesicles where it
is stored fo later released by exocytosis or used as a substrate for the synthesis
of norepinpehrine

dopamine B-hydroxylase - ANSWER converts dopamine to norepinephrine

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