Basic Clinical Pharmacology 15TH Edition
Test Exam Questions and Answers Verified
Solutions Latest Update 2026/2027
Question:
2. Drugs that have a significant first-pass effect:
1. Must be given by the enteral (oral) route only
2. Bypass the hepatic circulation
3. Are rapidly metabolized by the liver and may have little if any desired
action
4. Are converted by the liver to more active and fat-soluble forms
Answer:
3. Are rapidly metabolized by the liver and may have little if
any desired action
Question:
3. The route of excretion of a volatile drug will likely be the:
1. Kidneys
2. Lungs
3. Bile and feces
4. Skin
Answer:
2. Lungs
Question:
4. Medroxyprogesterone (Depo Provera) is prescribed intramuscularly
(IM) to create a storage reservoir of the drug. Storage reservoirs:
1. Assure that the drug will reach its intended target tissue
2. Are the reason for giving loading doses
3. Increase the length of time a drug is available and active
4. Are most common in collagen tissues
, Answer:
3. Increase the length of time a drug is available and active
Question:
5. The NP chooses to give cephalexin every 8 hours based on
knowledge of the drug's:
1. Propensity to go to the target receptor
2. Biological half-life
3. Pharmacodynamics
4. Safety and side effects
Answer:
2. Biological half-life
Question:
6. Azithromycin dosing requires that the first day's dosage be twice
those of the other 4 days of the prescription. This is considered a loading dose. A loading dose:
1. Rapidly achieves drug levels in the therapeutic range
2. Requires four- to five-half-lives to attain
3. Is influenced by renal function
4. Is directly related to the drug circulating to the target tissues
Answer:
1. Rapidly achieves drug levels in the therapeutic range
Question:
The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect
is the:
1. Minimum adverse effect level
2. Peak of action
3. Onset of action
4. Therapeutic range
Answer:
3. Onset of action
Test Exam Questions and Answers Verified
Solutions Latest Update 2026/2027
Question:
2. Drugs that have a significant first-pass effect:
1. Must be given by the enteral (oral) route only
2. Bypass the hepatic circulation
3. Are rapidly metabolized by the liver and may have little if any desired
action
4. Are converted by the liver to more active and fat-soluble forms
Answer:
3. Are rapidly metabolized by the liver and may have little if
any desired action
Question:
3. The route of excretion of a volatile drug will likely be the:
1. Kidneys
2. Lungs
3. Bile and feces
4. Skin
Answer:
2. Lungs
Question:
4. Medroxyprogesterone (Depo Provera) is prescribed intramuscularly
(IM) to create a storage reservoir of the drug. Storage reservoirs:
1. Assure that the drug will reach its intended target tissue
2. Are the reason for giving loading doses
3. Increase the length of time a drug is available and active
4. Are most common in collagen tissues
, Answer:
3. Increase the length of time a drug is available and active
Question:
5. The NP chooses to give cephalexin every 8 hours based on
knowledge of the drug's:
1. Propensity to go to the target receptor
2. Biological half-life
3. Pharmacodynamics
4. Safety and side effects
Answer:
2. Biological half-life
Question:
6. Azithromycin dosing requires that the first day's dosage be twice
those of the other 4 days of the prescription. This is considered a loading dose. A loading dose:
1. Rapidly achieves drug levels in the therapeutic range
2. Requires four- to five-half-lives to attain
3. Is influenced by renal function
4. Is directly related to the drug circulating to the target tissues
Answer:
1. Rapidly achieves drug levels in the therapeutic range
Question:
The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect
is the:
1. Minimum adverse effect level
2. Peak of action
3. Onset of action
4. Therapeutic range
Answer:
3. Onset of action
