Ortho Pathophysiology
| Complete Exam Study
Guide, Practice Questions,
Answers & ATI Review
Material
, Ortho Pathophysiology
Study online at https://quizlet.com/_hxqts0
1. Intramembranous Bone Forma- occurs in flat bones; replacement of sheet-like connective
tion tissue membranes with bony tissue
2. Endochondral Bone Formation occurs in long bones; replacement of hyaline cartilage
with bony tissue
3. Compact Bone forms at periphery
formed when many Haversian systems are tightly packed
together (forms outer covering of bone)
4. Spongy (Cancellous) Bone filled with red marrow
less dense bone that forms the interior of bone
no Haversian systems
made up of plates of bone bordering cavities that contain
marrow
5. Periosteum forms the outer covering of the bone; contains os-
teoblasts, blood vessels, nerves, and lymphatics
severe pain when torn!
6. When is peak bone mass early adulthood after cessation of skeletal growth
achieved?
7. What does resorption begin to ex- beginning in the 4th decade of life
ceed formation?
8. Growth Hormone secreted by anterior pituitary & acts on resting chondro-
cytes to induce and maintain proliferation
9. Thyroid Hormone (T3) acts on proliferating chondrocytes to induce hypertrophy
directly stimulates EPO and bone marrow
10.
, Ortho Pathophysiology
Study online at https://quizlet.com/_hxqts0
Parathyroid Hormone Related activates PTH receptor and maintains proliferation of
Protein (PRHrP) chondrocytes
11. Osteoblasts secrete extracellular matrix including collagen before ma-
turing into osteocytes
*control calcium and mineral deposition and are stimulat-
ed by calcitonin and is derived from mesenchymal stem
cells
12. Osteocytes located inside bone (formed from some of the os-
teoblasts)
13. Osteoclasts come from bone marrow to resorb bone; inhibited by
calcitonin
14. Diaphysis thin shaft between two larger ends
formed of compact bone surrounding a medullary cavity
containing marrow
15. Metaphysis where the shaft broadens into epiphysis
16. Epiphysis made of spongy bone covered by compact bone
each end covered by hyaline cartilage which facilitates
movement at points of articulation between bones
17. Epiphyseal Plate site of longitudinal bone growth in children/adolescents
18. Osteopenia bone mass 1-2.5 SD below mean peak bone mass of
young adults; midpoint to osteoporosis
19. Osteoporosis bone mass at least 2.5 SD below mean peak bone mass
of young adults; caused by loss of calcium salts (decrease
in bone mass and density)
| Complete Exam Study
Guide, Practice Questions,
Answers & ATI Review
Material
, Ortho Pathophysiology
Study online at https://quizlet.com/_hxqts0
1. Intramembranous Bone Forma- occurs in flat bones; replacement of sheet-like connective
tion tissue membranes with bony tissue
2. Endochondral Bone Formation occurs in long bones; replacement of hyaline cartilage
with bony tissue
3. Compact Bone forms at periphery
formed when many Haversian systems are tightly packed
together (forms outer covering of bone)
4. Spongy (Cancellous) Bone filled with red marrow
less dense bone that forms the interior of bone
no Haversian systems
made up of plates of bone bordering cavities that contain
marrow
5. Periosteum forms the outer covering of the bone; contains os-
teoblasts, blood vessels, nerves, and lymphatics
severe pain when torn!
6. When is peak bone mass early adulthood after cessation of skeletal growth
achieved?
7. What does resorption begin to ex- beginning in the 4th decade of life
ceed formation?
8. Growth Hormone secreted by anterior pituitary & acts on resting chondro-
cytes to induce and maintain proliferation
9. Thyroid Hormone (T3) acts on proliferating chondrocytes to induce hypertrophy
directly stimulates EPO and bone marrow
10.
, Ortho Pathophysiology
Study online at https://quizlet.com/_hxqts0
Parathyroid Hormone Related activates PTH receptor and maintains proliferation of
Protein (PRHrP) chondrocytes
11. Osteoblasts secrete extracellular matrix including collagen before ma-
turing into osteocytes
*control calcium and mineral deposition and are stimulat-
ed by calcitonin and is derived from mesenchymal stem
cells
12. Osteocytes located inside bone (formed from some of the os-
teoblasts)
13. Osteoclasts come from bone marrow to resorb bone; inhibited by
calcitonin
14. Diaphysis thin shaft between two larger ends
formed of compact bone surrounding a medullary cavity
containing marrow
15. Metaphysis where the shaft broadens into epiphysis
16. Epiphysis made of spongy bone covered by compact bone
each end covered by hyaline cartilage which facilitates
movement at points of articulation between bones
17. Epiphyseal Plate site of longitudinal bone growth in children/adolescents
18. Osteopenia bone mass 1-2.5 SD below mean peak bone mass of
young adults; midpoint to osteoporosis
19. Osteoporosis bone mass at least 2.5 SD below mean peak bone mass
of young adults; caused by loss of calcium salts (decrease
in bone mass and density)
