Pathophysiology -
Gastrointestinal
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, Pathophysiology - Gastrointestinal
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1. What is anorexia? lack of desire to eat despite physiologic stimuli that would normally produce
hunger
(not the same as anorexia nervosa)
2. What is the vom- medulla oblongata
iting center?
3. What are exam- - serotonin antagonist
ples of antiemet- - neurokinin antagonist
ic medications? - metoclopramide
- doperidone
- olanzapine
- corticosteroid
- apomorphine
- levodopa
- bromocriptine
4. What are the - fluid and electrolyte imbalance
complications of - acid-base disturbance
excessive vomit- - hyponatremia
ing? - hypokalemia
- hypochloremia
- metabolic alkalosis
5. What is projectile spontaneous vomiting that does not follow nausea or retching
vomiting?
6. What is retching? reverse movement of the stomach and esophagus without the expulsion of vom-
itus
7. 2-3 times per day to once per week
, Pathophysiology - Gastrointestinal
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What is normal
bowel movement
frequency?
8. Define constipa- infrequent or difficulty defecating
tion
9. What is normal normal rate of stool passage but difficulty with stool evacuation
transit (function-
al) constipation?
10. What causes nor- - low residue and low fluid diet
mal transit (func- - sedentary lifestyle
tional) constipa-
tion?
11. What is slow tran- impaired colonic motor actiity with infrequent bowel movements.
sit constipation?
12. What is pelvic failure of pelvic floor muscles or anal sphincter to relax or control
floor dysfunc-
tion?
13. What are caus- - disease process (cancer blockage)
es of secondary - diet
constipation? - medications (opioids)
14. What is the clin- Two of the following for at least 3 months
ical definition of - straining with defecation 25% of the time
constipation? - incomplete emptying 25% of the time
- manual maneuvers to facilitate stool evacuation for 25% of defecations
- fewer than 3 bowel movements per week
15. hard, dry stool retained in the rectum