Trauma pathophysiology
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Material
, Trauma pathophysiology
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1. 1st line of defense physical & mechanical barriers
-tightly bound epithelial cells fight of bacteria
-skin, GI, GU, respiratory
2. biochemical barriers part of 1st line of defense; trap or destroy pathogens
-mucus, perspiration, saliva, tears, earwax
3. 2nd line of defense inflammatory response
-redness, heat, swelling, pain
-microcirculatory:
-> blood vessel dilation
-> Increase vascular permeability
-> migration of WBC to site of injury
4. stress response initiated by CNS & endocrine system
-begins in limbic system
-results in release of catecholamines from adrenal gland & ultimately
release cortisol
5. alpha 1 catecholamine receptor
-increase smooth muscle contraction
6. alpha 2 catecholamine receptor
-GI & vessel muscle contraction, platelet aggregation, insulin secretion
7. beta 1 catecholamine receptor
-increase cardiac contraction (contractility & rate)
8. beta 2 catecholamine receptor
-bronchial/vessel/GI/GU muscle relaxation, gluconeogenesis, releases
insulin
9. epinephrine
1/7
| Complete Exam Study
Guide, Practice Questions,
Answers & ATI Review
Material
, Trauma pathophysiology
Study online at https://quizlet.com/_hp64hp
1. 1st line of defense physical & mechanical barriers
-tightly bound epithelial cells fight of bacteria
-skin, GI, GU, respiratory
2. biochemical barriers part of 1st line of defense; trap or destroy pathogens
-mucus, perspiration, saliva, tears, earwax
3. 2nd line of defense inflammatory response
-redness, heat, swelling, pain
-microcirculatory:
-> blood vessel dilation
-> Increase vascular permeability
-> migration of WBC to site of injury
4. stress response initiated by CNS & endocrine system
-begins in limbic system
-results in release of catecholamines from adrenal gland & ultimately
release cortisol
5. alpha 1 catecholamine receptor
-increase smooth muscle contraction
6. alpha 2 catecholamine receptor
-GI & vessel muscle contraction, platelet aggregation, insulin secretion
7. beta 1 catecholamine receptor
-increase cardiac contraction (contractility & rate)
8. beta 2 catecholamine receptor
-bronchial/vessel/GI/GU muscle relaxation, gluconeogenesis, releases
insulin
9. epinephrine
1/7
