Test Bank Basic and Clinical Pharmacology 15th Edition Bertram G Katzung Exam Questions Answers Study Resource

BASIC AND CLINICAL PHARMACOLOGY 15TH EDITION
KATZUNG TREVOR TEST BANK
INCLUSIVE OF CHAPTERS 1-66 COMPLETE WITH EXPLAINED ANSWERS

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Basic and Clinical Pharmacology 15th Edition Katzung Trevor Test Bank
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Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
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1.
A nurse working in radiology administers iodine to a patient who is hav
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ing a computed tomography (CT) scan. The nurse working on the oncolog
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y unit administers chemotherapy to patients who have cancer. At the Publi
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c Health Department, a nurse administers a measles-mumps-
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rubella (MMR) vaccine to a 14-month-
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old child as a routine immunization. Which branch of pharmacology best d
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escribes the actions of all three nurses?
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A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:

Pharmacology is the study of the biologic effects of chemicals. Nurses are
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kinvolved with clinical pharmacology or pharmacotherapeutics, which is a
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branch of pharmacology that deals with the uses of drugs to treat, prevent,
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qkand diagnose disease. The radiology nurse is administering a drug to help
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kdiagnose a disease. The oncology nurse is administering a drug to help tre
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at a disease. Pharmacoeconomics includes any costs involved in drug thera
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py.
Pharmacodynamics involves how a drug affects the body and pharmacokinet qk qk qk qk qk qk qk qk qk


ics is how the body acts on the body.
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2.
When involved in phase III drug evaluation studies, w
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hat responsibilities would the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug study
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C) Monitoring and observing patients closely for adverse effects
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D) Conducting research to determine effectiveness of the drug
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Ans: C
Feedback:

Phase III studies involve use of a drug in a vast clinical population in whic
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h patients are asked to record any symptoms they experience while taking
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the drugs. Nurses may be responsible for helping collect and analyze the i
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nformation to be shared with the Food and Drug Administration (FDA) but
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kwould not conduct research independently because nurses do not prescribe
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medications. Use of animals in drug testing is done in the preclinical trial
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s. Select patients who are involved in phase II studies to participate in stu
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dies where the participants have the disease the drug is intended to treat.
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These patients are monitored closely for drug action and adverse effects. P
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hase I studies involve healthy human volunteers who are usually paid for t
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heir participation. Nurses may observe for adverse effects and toxicity.
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3.
A physician has ordered intramuscular (IM) injections of morphine, a n
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arcotic, every 4 hours as needed for pain in a motor vehicle accident victi
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m. The nurse is aware this drug has a high abuse potential. Under what cat
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egory would morphine be classified?
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A) Schedule I qk




B) Schedule II qk




C) Schedule III qk




D) Schedule IV qk




Ans: B
Feedback:

Narcotics with a high abuse potential are classified as Schedule II drugs
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because of severe dependence liability. Schedule I drugs have high abuse
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potential and no accepted medical use. Schedule III drugs have a lesser
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abuse potential than II and an accepted medical use. Schedule IV drugs ha
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ve low abuse potential and limited dependence liability.
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4.
What concept is considered when generic drugs are substituted for br
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and name drugs?qk qk




A) Bioavailability

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B) Critical concentration qk




C) Distribution
D) Half-life
Ans: A
Feedback:

Bioavailability is the portion of a dose of a drug that reaches the systemi
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c circulation and is available to act on body cells. Binders used in a gene
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ric drug may not be the same as those used in the brand name drug. The
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refore, the way the body breaks down and uses the drug may differ, whic
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h may eliminate a generic drug substitution. Critical concentration is the a
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mount of a drug that is needed to cause a therapeutic effect and should n
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ot differ between generic and brand name medications. Distribution is the
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qkphase of pharmacokinetics, which involves the movement of a drug to t
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he bodys tissues and is the same in generic and brand name drugs. A drug
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s half-
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life is the time it takes for the amount of drug to decrease to half the pea
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k level, which should not change when substituting a generic medication
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.


5.
A nurse is assessing the patients home medication use. After listening to
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the patient list current medications, the nurse asks what priority question
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?
A) Do you take any generic medications?
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B) Are any of these medications orphan drugs?
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C) Are these medications safe to take during pregnancy?
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D) Do you take any over-the-counter medications?
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Ans: D
Feedback:

It is important for the nurse to specifically question use of over-the-
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counter medications because patients may not consider them important. T
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he patient is unlikely to know the meaning of orphan drugs unless they to
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o are health care providers. Safety during pregnancy, use of a generic me
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dication, or classification of orphan drugs are things the patient would be
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unable to answer but could be found in reference books if the nurse wishes
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to research them.
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