What it the quaternary structure?
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The three dimensional shape of two or more proteins linked together.
What are five common excipients?
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-Stabilizers (protect from chemical degradation)
-Preservatives (prevent mold or bacterial growth)
-Fillers (ensure consistent dosing)
-Flavours
-Colours
,What is a drug candidate?
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A picture of the active molecule on a sheet of paper.
What are Van der Waals interactions?
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Weak attractions between molecules that are close together as a result of
these charges. Their strength depends on the surface area.
When a base has a pH<pKa, in what form will the molecule be?
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Charged.
When and what was the Board of Food and Drug Inspection
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1907. Labelling only
,What is 60-70% of the cost of a new drug?
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Clinical trials
What is the main target for drug companies?
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Markets.
Why do companies identify 3 or 4 backup compounds for a drug candidate?
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If the primary compound fails, recovery time is minimized.
How does modular construction make life possible?
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Only one enzyme system is needed for each bimolecular type.
, What is the first step of a reaction?
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The enzyme and the substrate change shape to bind and form the ES
complex.
What is an investigational new drug (IND)?
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An application to the FDA to get a clinical trial.
What is an ideal compound in HTS testing?
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A compound that is specific (only active in one assay).
When a base has a pH>pKa, in what form will the molecule be?
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Neutral
Give this one a try later!
The three dimensional shape of two or more proteins linked together.
What are five common excipients?
Give this one a try later!
-Stabilizers (protect from chemical degradation)
-Preservatives (prevent mold or bacterial growth)
-Fillers (ensure consistent dosing)
-Flavours
-Colours
,What is a drug candidate?
Give this one a try later!
A picture of the active molecule on a sheet of paper.
What are Van der Waals interactions?
Give this one a try later!
Weak attractions between molecules that are close together as a result of
these charges. Their strength depends on the surface area.
When a base has a pH<pKa, in what form will the molecule be?
Give this one a try later!
Charged.
When and what was the Board of Food and Drug Inspection
Give this one a try later!
1907. Labelling only
,What is 60-70% of the cost of a new drug?
Give this one a try later!
Clinical trials
What is the main target for drug companies?
Give this one a try later!
Markets.
Why do companies identify 3 or 4 backup compounds for a drug candidate?
Give this one a try later!
If the primary compound fails, recovery time is minimized.
How does modular construction make life possible?
Give this one a try later!
Only one enzyme system is needed for each bimolecular type.
, What is the first step of a reaction?
Give this one a try later!
The enzyme and the substrate change shape to bind and form the ES
complex.
What is an investigational new drug (IND)?
Give this one a try later!
An application to the FDA to get a clinical trial.
What is an ideal compound in HTS testing?
Give this one a try later!
A compound that is specific (only active in one assay).
When a base has a pH>pKa, in what form will the molecule be?
Give this one a try later!
Neutral
