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Asthma Chronic disease due to
bronchoconstriction and an
excessive inflammatory response in
the bronchioles
,What are 5 s/s of asthma coughing
wheezing
shortnes
s of
breath
rapid
breathin
g chest
tightness
Pathophysiology of asthma (5) -airway inflammation, bronchial hyper-
reactivity and smooth muscle spasm
-excess mucus production and
accumulation
-hypertrophy of bronchial smooth muscle
-airflow obstruction
-decreased alveolar ventilation
Bronchioles smaller passageways that originate from
the bronchi that become the alveoli
3 layers of the bronchioles innermost layer
middle layer -
lamina propria
, outermost layer
lamina propria the middle layer of the bronchioles
structure of the lamina propria embedded with connective tissue cells
and immune cells
purpose of the lamina propria white blood cells are present to help
protect the airways
How does the lamina propria effect the lungs in regards the
WBCs protective feature goes into overdrive causing an
inflammatory to asthma response that damages host tissue
What does the innermost layer of the bronchioles contain columnar
epithelial ells and mucus producing goblet cells
What does the outermost layer of the
bronchioles smooth
muscle cells contain
what does the outermost layer of the bronchioles docontrol the airways
ability to constrict and dilate