ASCP CG Certification Practice 2025 UPDATE LATEST EXAM
VERSION MOST TESTED QUESTIONS WITH VERIFIED
ANSWERS GRADED A+ ASSURED SUCCESS
What is the best agent to use against mycoplasma? – Correct Answer✅✅: BM
cyclin - a combination of two antibiotics (tiamulin and minocycline) that effecticely
targets mycoplasma growth
For successful harvest, each new batch of hypotonic solution should be evaluated by:
- Correct Answer✅✅: comparing the new lot to a lot already in use
Colagenase, pronase, and trypsin are: - Correct Answer✅✅: Proteolytic enzymes
- break down tissues into single-cell suspensions
When harvesting peripheral blood cultures, asceptic technique no longer matters
following incubation with: - Correct Answer✅✅: Colcemid - mitotic spindle
poison that halts cells at metaphase
,Samples that arrive at the cytogenetics lab should first be: - Correct Answer✅✅:
Logged in to the system
Phytohemagglutinin (PHA) stimulates which type of cells into division? – Correct
Answer✅✅: T-cell lymphocytes
To avoid culture failure, monitoring reagents is crucial. When logging a culture
failure, what is the MOST important to document? – Correct Answer✅✅:
Expiration dates of reagents used
Which type of microscope is used when cleaning a CVS (chorionic villus) sample? –
Correct Answer✅✅: Dissection
Which cell type is most problematic if found in a CVS (chorionic villus) sample? –
Correct Answer✅✅: Decidua (maternal tissue)
When looking at a slide under a phase contrast scope and a lot of cytoplasm is still
seen around the mets, what is the most likely cause? – Correct Answer✅✅:
innappropriate slide drying time
,What will help prevent microbial contamination and cross contamination of
cultures? – Correct Answer✅✅: Asceptic technique
When there are not enough mets to complete the study of a patient/case, what needs
to be done next? – Correct Answer✅✅: prepare additional slides from any
remaining sample
When looking at a dropped slide under a phase scope and mets are very spread out
and sparse, what could help fix the issue? – Correct Answer✅✅: Increading the
drying time by using warm slides
What is true of an inverted microscope? – Correct Answer✅✅: the objectives are
beneath the stage
High-resolution banding is indicated for a possible diagnosis of: - Correct
Answer✅✅: DiGenorge syndrome -- microdeletion of 22q11, also called
velocardiofacial syndrome
, "velo" - soft palette,
"cardio" - congenital heart defects,
"facial" - unique abnormal facial features, short philtrum (upper lip indent), tubular
nose, wide spread eyes, etc
When verifying if a specimen is appropriate for cytogenetic analysis, what is the
MOST important data to accompany the specimen? – Correct Answer✅✅:
Reason for referral
Which type of specimen should be requested for a cytogenetic analysis for turner
syndrome? – Correct Answer✅✅: Heparinized peripheral blood stored at room
temperature
(NOT FROZEN)
A blood sample can be used to study the cytogenetics of a malignancy only if: -
Correct Answer✅✅: Dividing leukemic cells are present in circulation
VERSION MOST TESTED QUESTIONS WITH VERIFIED
ANSWERS GRADED A+ ASSURED SUCCESS
What is the best agent to use against mycoplasma? – Correct Answer✅✅: BM
cyclin - a combination of two antibiotics (tiamulin and minocycline) that effecticely
targets mycoplasma growth
For successful harvest, each new batch of hypotonic solution should be evaluated by:
- Correct Answer✅✅: comparing the new lot to a lot already in use
Colagenase, pronase, and trypsin are: - Correct Answer✅✅: Proteolytic enzymes
- break down tissues into single-cell suspensions
When harvesting peripheral blood cultures, asceptic technique no longer matters
following incubation with: - Correct Answer✅✅: Colcemid - mitotic spindle
poison that halts cells at metaphase
,Samples that arrive at the cytogenetics lab should first be: - Correct Answer✅✅:
Logged in to the system
Phytohemagglutinin (PHA) stimulates which type of cells into division? – Correct
Answer✅✅: T-cell lymphocytes
To avoid culture failure, monitoring reagents is crucial. When logging a culture
failure, what is the MOST important to document? – Correct Answer✅✅:
Expiration dates of reagents used
Which type of microscope is used when cleaning a CVS (chorionic villus) sample? –
Correct Answer✅✅: Dissection
Which cell type is most problematic if found in a CVS (chorionic villus) sample? –
Correct Answer✅✅: Decidua (maternal tissue)
When looking at a slide under a phase contrast scope and a lot of cytoplasm is still
seen around the mets, what is the most likely cause? – Correct Answer✅✅:
innappropriate slide drying time
,What will help prevent microbial contamination and cross contamination of
cultures? – Correct Answer✅✅: Asceptic technique
When there are not enough mets to complete the study of a patient/case, what needs
to be done next? – Correct Answer✅✅: prepare additional slides from any
remaining sample
When looking at a dropped slide under a phase scope and mets are very spread out
and sparse, what could help fix the issue? – Correct Answer✅✅: Increading the
drying time by using warm slides
What is true of an inverted microscope? – Correct Answer✅✅: the objectives are
beneath the stage
High-resolution banding is indicated for a possible diagnosis of: - Correct
Answer✅✅: DiGenorge syndrome -- microdeletion of 22q11, also called
velocardiofacial syndrome
, "velo" - soft palette,
"cardio" - congenital heart defects,
"facial" - unique abnormal facial features, short philtrum (upper lip indent), tubular
nose, wide spread eyes, etc
When verifying if a specimen is appropriate for cytogenetic analysis, what is the
MOST important data to accompany the specimen? – Correct Answer✅✅:
Reason for referral
Which type of specimen should be requested for a cytogenetic analysis for turner
syndrome? – Correct Answer✅✅: Heparinized peripheral blood stored at room
temperature
(NOT FROZEN)
A blood sample can be used to study the cytogenetics of a malignancy only if: -
Correct Answer✅✅: Dividing leukemic cells are present in circulation
