NURS 3320 Exam 1 Medications
1. 1st gen/ typi- MOA: blocks the ettect of dopamine to help reduce psychotic symptoms
cal (EPS common) S/E: tardive dyskinesia (abnormal involuntary movements such as a lip smacking),
more neurologi- akathisia (uncomfortable restlessness), pseudoparkinsonism (slow shuffling gait,
cal s/e tremors, cogwheel rigidity...), dystonia (muscle stittness or rigidity), oculogyric
crisis-dystonic symptom (uncontrolled rolling back of eyes), neuroleptic malignant
syndrome, & seizures
2. 2nd gen/ nontyp- 2nd gen: block D@ & 5HT2A receptors
ical (less s/e & S/E: Increased cholesterol, menorrhagia (heavy menstrual bleeding), monitor
EPS) more meta- glucose in diabetics
bolic s/e Clozapine: may cause agranulocytosis, severe neutropenia, bradycardia, syncope,
seizures, myocarditis, & cardiomyopathy. Must monitor WBCc, absolute neutrophil
count (ANC), & note nay flu like symptoms. Best med for refractory schizophrenia
3. SSRIs (selective Sertraline (Zoloft)
serotonin reup- Escitalopram (Lexapro)
take inhibitors) Fluoxetine (Prozac)
(6) Paroxetine (Paxil)
Citalopram (Celexa)
Fluvoxamine (Luvox)
4. MAOIs Phenelzine (Nardil)
(monoamine Isocarboxazid (Marplan)
oxidase Tranylcypromine (Parnate)
inhibitors) (4) Selegiline (Emsam) *Patch
5. SNRIs Venlafaxine (Ettexor)
(serotonin-nor- Duloxetine (Cymbalta)
epinephrine Desvenlafaxine (Pristiq)
reuptake
inhibitors) (3)
6.
1/5
, NURS 3320 Exam 1 Medications
TCAs (tricyclic an- Amitriptyline (Elavil)
tidepressants) (5) Nortriptyline (Pamelor)
Imipramine (Tofranil)
Clomipramine (Anafranil)
Desipramine (Norpramine)
7. Atypicals Antide- Bupropion (Wellbutrin)
pressants (6) Trazodone (Desyrel)
Vortioxetine (Trintellix)
Nefazodone (Serzone)
Vilazodone (Viibryd)
Mirtazapine (Remeron)
8. SSRIs (selective - Common s/e weight gain, insomnia, nausea, sexual dysfunction
serotonin reup- - Fewest s/e of all antidepressants
take inhibitors) - Good for use in adults with SI, least risk of suicide by OD
- Increased SO notes in children/ adolescents
- Avoid anticoagulants, other serotonin agonists, (triptans), opiate derivatives, &
lithium
9. MAOIs - Takes 2-4 weeks for therapeutic ettects
(monoamine - Monitor BP & HR for orthostatic changes
oxidase - Follow a tyramine free diet
inhibitors) - Contraindications: SSRIs, TCAs, buspirone (BuSpar), opiate derivatives, dex-
tromethorphan
- Use cautiously w/ diabetes, seizures disorders, or w/ antihypertensive use
- Contraindications: pheochromocytoma, heart, vascular or kidney dysfunction
- Has the only medication that can be used transdermal
10. TCAs (tricyclic an- - Takes 4-8 weeks to take full ettect
tidepressants) - Take at night in a single daily dose
- Cause anticholinergic s/e
- Common s/e: sedation, hypotension, increased appetite/ weight gain, & toxicity,
2/5
1. 1st gen/ typi- MOA: blocks the ettect of dopamine to help reduce psychotic symptoms
cal (EPS common) S/E: tardive dyskinesia (abnormal involuntary movements such as a lip smacking),
more neurologi- akathisia (uncomfortable restlessness), pseudoparkinsonism (slow shuffling gait,
cal s/e tremors, cogwheel rigidity...), dystonia (muscle stittness or rigidity), oculogyric
crisis-dystonic symptom (uncontrolled rolling back of eyes), neuroleptic malignant
syndrome, & seizures
2. 2nd gen/ nontyp- 2nd gen: block D@ & 5HT2A receptors
ical (less s/e & S/E: Increased cholesterol, menorrhagia (heavy menstrual bleeding), monitor
EPS) more meta- glucose in diabetics
bolic s/e Clozapine: may cause agranulocytosis, severe neutropenia, bradycardia, syncope,
seizures, myocarditis, & cardiomyopathy. Must monitor WBCc, absolute neutrophil
count (ANC), & note nay flu like symptoms. Best med for refractory schizophrenia
3. SSRIs (selective Sertraline (Zoloft)
serotonin reup- Escitalopram (Lexapro)
take inhibitors) Fluoxetine (Prozac)
(6) Paroxetine (Paxil)
Citalopram (Celexa)
Fluvoxamine (Luvox)
4. MAOIs Phenelzine (Nardil)
(monoamine Isocarboxazid (Marplan)
oxidase Tranylcypromine (Parnate)
inhibitors) (4) Selegiline (Emsam) *Patch
5. SNRIs Venlafaxine (Ettexor)
(serotonin-nor- Duloxetine (Cymbalta)
epinephrine Desvenlafaxine (Pristiq)
reuptake
inhibitors) (3)
6.
1/5
, NURS 3320 Exam 1 Medications
TCAs (tricyclic an- Amitriptyline (Elavil)
tidepressants) (5) Nortriptyline (Pamelor)
Imipramine (Tofranil)
Clomipramine (Anafranil)
Desipramine (Norpramine)
7. Atypicals Antide- Bupropion (Wellbutrin)
pressants (6) Trazodone (Desyrel)
Vortioxetine (Trintellix)
Nefazodone (Serzone)
Vilazodone (Viibryd)
Mirtazapine (Remeron)
8. SSRIs (selective - Common s/e weight gain, insomnia, nausea, sexual dysfunction
serotonin reup- - Fewest s/e of all antidepressants
take inhibitors) - Good for use in adults with SI, least risk of suicide by OD
- Increased SO notes in children/ adolescents
- Avoid anticoagulants, other serotonin agonists, (triptans), opiate derivatives, &
lithium
9. MAOIs - Takes 2-4 weeks for therapeutic ettects
(monoamine - Monitor BP & HR for orthostatic changes
oxidase - Follow a tyramine free diet
inhibitors) - Contraindications: SSRIs, TCAs, buspirone (BuSpar), opiate derivatives, dex-
tromethorphan
- Use cautiously w/ diabetes, seizures disorders, or w/ antihypertensive use
- Contraindications: pheochromocytoma, heart, vascular or kidney dysfunction
- Has the only medication that can be used transdermal
10. TCAs (tricyclic an- - Takes 4-8 weeks to take full ettect
tidepressants) - Take at night in a single daily dose
- Cause anticholinergic s/e
- Common s/e: sedation, hypotension, increased appetite/ weight gain, & toxicity,
2/5
