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NU 641 ADVANCED CLINICAL PHARMACOLOGY EXAM 1 QUESTIONS AND CORRECT ANSWERS LATEST UPDATE 2026/2027 .

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1. When should thiazides NOT be used? correct answer if creatinine clearance is lessthan 30-50 ml/min 2. True or False Thiazide diuretics is a first-line hypertensive agent and will also help to de-crease fluid retention correct answer True 3. Calcium Channel Blockers MOA correct answer Cause coronary artery vasodilation Cause peripheral arterial vasodilation, thus decreasing systemic vascular resistance Reduce the workload of the heart Result correct answer decreased myocardial oxygen demand (Hypertension, dysrhythmias, angina, and Raynaud's) 4. Examples of CCBs correct answer Verapamil, diltiazem, amlodipine, nifedipine 5. Indications for Verapamil correct answer essential HTN, angina (chronic stable, unstable), ventricular rate control in arrhythmia, dysrhythmias. 6. gentamicin side/adverse effects correct answer ototoxicity, nephrotoxicity, hypersensitivity 7. What classifies a diagnosis of hypertension correct answer 2 elevated blood pressures at separate oflce visits One elevated BP reading does not constitute hypertension (White coat syndr

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NU 641 ADVANCED CLINICAL

PHARMACOLOGY EXAM 1 QUESTIONS

AND CORRECT ANSWERS LATEST

UPDATE 2026/2027 .

, 1. When should thiazides NOT be used?✔✔ correct answer if creatinine clearance is less than 30-50 ml/min


2. True or False

Thiazide diuretics is a first-line hypertensive agent and will also help to de-crease fluid retention✔✔ correct

answer True

3. Calcium Channel Blockers MOA✔✔ correct answer Cause coronary artery vasodilation Cause

peripheral arterial vasodilation, thus decreasing systemic vascular resistance Reduce the workload of the heart

Result✔✔ correct answer decreased myocardial oxygen demand (Hypertension,

dysrhythmias, angina, and Raynaud's)

4. Examples of CCBs✔✔ correct answer Verapamil, diltiazem, amlodipine, nifedipine


5. Indications for Verapamil✔✔ correct answer essential HTN, angina (chronic stable, unstable), ventricular rate control in arrhythmia, dysrhythmias.

6. gentamicin side/adverse effects✔✔ correct answer ototoxicity, nephrotoxicity, hypersensitivity


7. What classifies a diagnosis of hypertension✔✔ correct answer 2 elevated blood pressures at separate oflce visits

One elevated BP reading does not constitute hypertension (White coat syndrome)

8. What hypertensive medications work extremely well in the black and elderly

white population?✔✔ correct answer Thiazide medication. (diuretics)

This is because these medications have been shown to decrease morbidity and mortality in this population.

9. For the black and elderly population, What happens to the body when they are on a antihypertensive for 6 months

to a year?✔✔ correct answer The body will be seeking homeostasis.

10. Angiotensin II✔✔ correct answer increases blood pressure by stimulating kidneys to reabsorb more water aldosterone

Vasoconstrictor


11. What structural changes does angiotensin II do to the heart?✔✔ correct answer Hypertrophy Remodeling.

12. True or False

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