NURS 5663 Quiz 1 Pharmacology Full Questions and Answers 2026 Update 100% Correct - Texas Woman's University.

Based on changes in hepatic function in older adult patients, which adjustment should the nurse expect for oral medications that undergo extensive first pass metabolism? A. A higher dose should be used with the same time schedule. B. The interval between doses should be increased. C. No change is necessary; metabolism will not be affected. D. The interval between doses should be reduced. 2. Which types of drugs taken by a pregnant patient are more likely to have effects on a fetus? a. Drugs that are highly polar b. Ionized drugs c. Lipid-soluble drugs d. Protein- bound drugs 3. Which of the following locations for genetic variations may affect drug pharmacodynamics? a. Drug- transporter proteins b. Drug target proteins and drug- metabolizing enzymes c. Drug-metabolizing enzymes d. Drug target proteins 4. Which of the following is true regarding herbal supplements? a. Safety and efficacy are proven by manufacturer b. Purity and contents are regulated c. Active ingredient may not be identified d. Active ingredient is identified. 5. Which of the following medications would require a dose adjustment in a patient with hepatic insufficiency? a. Metronidazole b. Ciprofloxacin c. Vancomycin d. Cefazolin 6. Which of the following is contraindicated in a patient being treated with monoamine oxidase inhibitor? a. Tramadol b. Hydrocodone/acetaminophen (Vicodin) c. Oxycodone (Oxycontin) 7. The dosing of morphine in an infant to control pain typically requires using higher doses than an adult. The major reason for the higher dosing is : a. Reduced entry of drug into the CNS b. Increased binding of drug to plasma proteins. c. Increased clearance of drug d. Reduced metabolism of drug e. Reduced opiate sensitivity in young children In infants, their immature liver and kidneys contribute to a faster clearance rate for drugs like morphine, requiring higher doses to achieve the desired therapeutic effect.