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APEA Major Questions and Correct Detailed Answers – APEA – 2025/2026 Complete Exam Practice Questions with Answers

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This document contains APEA major exam questions with detailed correct answers covering women’s health, obstetrics, gynecology, primary care, men’s health, infectious diseases, endocrinology, neurology, and preventive care. The material includes clinical scenarios, diagnostic criteria, treatment recommendations, screening guidelines, and evidence-based management strategies commonly tested on APEA examinations. It serves as a comprehensive review resource for certification preparation and clinical practice assessment across multiple advanced practice nursing topics

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Page |1


APEA MAJOR QUESTIONS AND CORRECT
DETAILED ANSWERS


Which one of the following is an ethical infraction when using
electronic medical records?

Ans: Copying and pasting outdated notes


Practice authority for advanced practice registered nurses (APRNs) is
granted by:

Ans: each state's board of nursing


Which answer is true about full practice authority for nurse
practitioners?

Ans: Full practice authority is the authorization of nurse
practitioners to evaluate patients; diagnose, order and interpret
diagnostic tests; and to initiate and manage treatments—
including prescribing medications—without required physical
collaboration or supervision.


Which of the following scenarios reflects "incident to" billing for
Medicare-covered services?

All rights reserved © 2025/ 2026 |

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Ans: An NP bills 100% of the allowable Medicare fee schedule
for follow-up care


The scope of practice for nurse practitioners is determined by:

Ans: the state government


Medicare Part B covers

Ans: physician services, outpatient services, and durable
medical equipment


Select the statement that best describes the role of a women's health
nurse practitioner (WHNP)

Ans: The role of the WHNP is to assess, diagnose, and treat the
healthcare needs of women throughout their lifespan


Statistical significance is represented by the P value. Which statement
about P value is correct?

Ans:




All rights reserved © 2025/ 2026 |

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When counseling a patient diagnosed with generalized anxiety
disorder (GAD) or panic disorder, lifestyle modifications to decrease
symptoms should include

Ans: exercising vigorously for 20 minutes three times a week


Which of the following is used to evaluate suspected obstructive sleep
apnea (OSA) in patients who present with a sleep disorder?

Ans: Polysomnography


Why is it often challenging to differentiate between the diagnosis of
major depressive disorder (MDD) and bipolar disorder?

Ans: Patients with bipolar disorder often present for treatment
during their low mood


Which statement about grief/bereavement and major depressive
disorder (MDD) is correct?

Ans: Depression cannot be distinguished from
grief/bereavement for at least 1 year after a loss


The first-line drug class for the treatment of patients with generalized
anxiety disorder (GAD) is

Ans: selective serotonin reuptake inhibitors (SSRIs)

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Which of the following tools is considered the validated screening tool
for identifying generalized anxiety disorder (GAD)?

Ans: Generalized Anxiety Disorder questionnaire


When initiating pharmacologic treatment for depression, what is the
recommended interval for monitoring therapeutic effects?

Ans: Every 2-4 weeks until therapeutic dose is reached


According to DSM-5 criteria, what core symptoms must be present to
diagnosis major depressive disorder (MDD)?

Ans: Anhedonia


Because of the high prevalence of postpartum depression, screening is
recommended for all women in the perinatal period. The evidence-
based tool recommended for outpatient perinatal and postpartum
depression screening is the:

Ans: Edinburgh scale


The highly sensitive and specific assessment tool that should be used in
primary care to evaluate patients suspected of alcohol use disorder
(AUD) is:

All rights reserved © 2025/ 2026 |

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