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NRNP 6675 Final Exam Questions and Answers with rationales (Latest 2026 / 2027): Most Comprehensive to Pass the Exam, 100% Verified - UPDATED

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Pass NRNP 6675 Final Exam with this 2026/2027 actual Q&A study guide with rationales. Covers PMHNP psychopharmacology, DSM-5, ethics, & psychotherapy!

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NRNP 6675 Final Exam Questions and
Answers with rationales (Latest ):
Most Comprehensive to Pass the Exam,
100% Verified - UPDATED

The Tarasoff ruling requires therapists to:
A) Maintain strict confidentiality under all circumstances.
B) Warn and protect an identifiable victim of a credible threat.
C) Report all homicidal ideations to the police immediately.
D) Document threats but take no external action.
Answer: B
Rationale: Tarasoff established the "duty to warn and protect" an identifiable
third party when a patient makes a credible threat of serious harm.
A patient on Lithium presents with coarse tremors, confusion, and ataxia. What is
the priority intervention?
A) Administer a beta-blocker.
B) Check serum Lithium levels and prepare for possible hemodialysis.
C) Reduce the Lithium dose by 50%.
D) Switch to Valproic acid immediately.
Answer: B
Rationale: These are signs of Lithium toxicity. Severe toxicity requires immediate
cessation of the drug, checking levels, and potentially hemodialysis.
Which medication requires patients to be enrolled in a REMS program due to the
risk of agranulocytosis?

,A) Olanzapine
B) Clozapine
C) Quetiapine
D) Aripiprazole
Answer: B
Rationale: Clozapine carries a high risk of agranulocytosis, requiring strict ANC
monitoring via the REMS program.
What is the first-line treatment for mild to moderate major depressive disorder in
pregnancy?
A) Sertraline
B) Cognitive Behavioral Therapy (CBT)
C) Electroconvulsive therapy (ECT)
D) Venlafaxine
Answer: B
Rationale: Non-pharmacological interventions, particularly CBT, are
recommended as first-line for mild-to-moderate depression in pregnancy to avoid
fetal medication exposure.
A patient with schizophrenia is taking Haloperidol and develops a temperature of
103°F, muscle rigidity, and altered mental status. What condition is this?
A) Serotonin Syndrome
B) Neuroleptic Malignant Syndrome (NMS)
C) Tardive Dyskinesia
D) Akathisia
Answer: B
Rationale: NMS is a life-threatening reaction to antipsychotics characterized by
hyperthermia, severe muscle rigidity, and autonomic instability.

,Which of the following is a black box warning for Fluoxetine in the pediatric
population?
A) Sudden cardiac death
B) Suicidal ideation and behavior
C) Hepatotoxicity
D) Severe skin reactions
Answer: B
Rationale: Antidepressants carry a black box warning for increased risk of suicidal
thinking and behavior in children, adolescents, and young adults.
A patient with PTSD is prescribed Prazosin. What symptom is this primarily
targeting?
A) Avoidance
B) Hyperarousal
C) Nightmares
D) Dissociation
Answer: C
Rationale: Prazosin, an alpha-1 adrenergic antagonist, is used off-label to reduce
trauma-related nightmares in PTSD.
According to DSM-5-TR, how long must depressive symptoms persist to diagnose
Persistent Depressive Disorder (Dysthymia)?
A) 2 weeks
B) 1 month
C) 2 years
D) 5 years
Answer: C

, Rationale: PDD requires a depressed mood for most of the day, for more days
than not, for at least two years.
What is the mechanism of action of Bupropion?
A) Selective serotonin reuptake inhibition
B) Norepinephrine-dopamine reuptake inhibition (NDRI)
C) Serotonin-norepinephrine reuptake inhibition (SNRI)
D) Monoamine oxidase inhibition
Answer: B
Rationale: Bupropion inhibits the reuptake of norepinephrine and dopamine, with
minimal effect on serotonin.
A patient taking an MAOI eats aged cheese. What emergency condition are they
at risk for?
A) Neuroleptic Malignant Syndrome
B) Hypertensive Crisis
C) Serotonin Syndrome
D) Lithium Toxicity
Answer: B
Rationale: Tyramine in aged foods displaces norepinephrine from storage vesicles,
causing a dangerous hypertensive crisis in patients on MAOIs.
Which assessment tool is specifically designed to screen for Alcohol Use Disorder?
A) PHQ-9
B) GAD-7
C) AUDIT-C
D) PCL-5
Answer: C

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