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ANFS 300 EXAM 3 QUESTIONS WITH VERIFIED ANSWERS

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ANFS 300 EXAM 3 QUESTIONS WITH VERIFIED ANSWERS

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ANFS 300 EXAM 3 QUESTIONS WITH VERIFIED
ANSWERS


DNA methylation - Answers - Association of lysine 9 methylated histones with DNA
promotes methylation of cytosine

Epigenetics - Answers - Histone modification and DNA methylation can be inherited by
daughter cells

What is epigenetics the basis of - Answers - Epigenetic inheritance and imprinting

Insulin like growth factor 2 - Answers - Parental side

H19 - Answers - Maternal side

Synonymous mutations - Answers - Codon specifies same amino acid (wobble effect)

Missense mutations - Answers - Conservative: codon specifies chemically similar amino
acid, Nonconservative: codon specifies different amino acids

Nonsense mutations - Answers - Codon for one amino acid is changed into a translation
terminaiton

Frameshift mutation - Answers - Insertion or deletion of one of more nucleotides, results
in a change of the translational reading frame

Open reading frames - Answers - These mutation directly effect protein structure, Could
lead to loss of function or gain of function

Regulatory/non coding genes - Answers - These mutations directly effect expression
patterns

Somatic mutations - Answers - Mutations occurring in somatic cells during development
or in adulthood, Not inherited because not in germ line

Germline mutations - Answers - Mutations that occur in the cell lineage that is destined
to become gametes

Fragile X syndrome - Answers - Typical individual has around 30 CGG repeats

Hardy-Weinberg Equilibrium - Answers - P2 + 2PQ + Q2 = 1

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