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Med Surg 2 HESI Study Guide 2026 | Key Concepts, Practice Questions, Verified Answers & Comprehensive Exam Review

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Prepare for your Med Surg 2 HESI exam with this comprehensive study guide featuring key concepts, practice questions, verified answers, and detailed rationales. Covers cardiovascular, respiratory, endocrine, neurological, renal, gastrointestinal, musculoskeletal, oncology, infectious diseases, fluid and electrolyte balance, pharmacology, patient safety, delegation, prioritization, and clinical judgment. An excellent resource for HESI exams, Medical-Surgical Nursing coursework, and NCLEX-RN preparation.

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© lec_Bismark | Educational Resources1




Hesi Med Surg Study Guide Key Concepts and
practice Questions With Verified Answers
Latest Update 2026


1.Penicillin G procaine 240,000 units intramuscularly is prescribed for a 4-year-
old child who has a streptococcal respiratory infection. The medication vial is
labeled 1,200,000 units/2 mL. How many mL should the nurse administer? (Enter
numeric value only. If rounding is required, round to the nearest tenth.) 0.4 mL



2. A 4-year-old is admitted with a group and receives a prescription for a single
dose of dexamethasone 0.6 mg/kg IM. The child weighs 35 pounds. How many mg
should the nurse administer? (Enter numerical value only. If rounding is required,
round to the nearest whole number.) 10

3. Following a motor vehicle accident, a client with chest trauma receives a chest
tube to relieve a hemothorax. Two hours following the chest tube insertion, the
nurse observes the water level in the water-seal chamber is rising during inspiration
and falling during expiration. Which action should the nurse implement? Continue
to monitor the drainage system.

4. A client with a cervical spinal injury (C7) is experiencing autonomic dysreflexia.
The nurse should first assess the client for which precipitating factor?

An acutely distended bladder.




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, © lec_Bismark | Educational Resources2




5.A client with a cervical spinal injury (C7) is experiencing autonomic
dysreflexia. The nurse should first assess the client for which precipitating factor?
An acutely distended bladder.



6.The nurse is admitting a client with possible tuberculosis (TB). The client is placed
in a private room with airborne precautions pending diagnostic test results. Which
diagnostic test should the nurse review to confirm the diagnosis of TB?

Sputum culture positive for Mycobacterium tuberculosis.



7.Lactulose was prescribed two days ago for a client who was recently diagnosed
with hepatic encephalopathy. The client is
confused and experiencing frequent loose stools. Laboratory findings show an
elevated serum ammonia (NH) level of 220μg/dL (157.1 μmol/dL). Which
action should the nurse take?

Reference Range:

Ammonia [10 to 80 μg/dL (6 to 47 μmol/L)] Continue the

prescribed dose of lactulose.

8. The nurse is obtaining the admission history for a client with suspected peptic
ulcer disease (PUD). Which subjective data
reported by the client supports this disease process? Upper mid abdominal pain
described as gnawing and burning.

9.A client with benign prostatic hyperplasia (BPH) is preparing for discharge
following a transurethral needle ablation (TUNA).




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, © lec_Bismark | Educational Resources3




Which information should the nurse include in the discharge instructions?
Monitor urinary stream for decrease in output.

10. The nurse is caring for a client receiving thrombolytic therapy following an
acute myocardial infarction (MI). Which nursing problem should the nurse
identify as a priority for this client? Risk for injury related to effects of
thrombolysis.

11. The nurse is caring for a client who had an appendectomy 4 hours ago. Which
finding requires immediate action by the nurse? High-pitched sound heard upon
inspiration.

12. An adult client newly diagnosed with left ventricular dysfunction is admitted
to the hospital with fine rales and wheezing. When assessing this client, which
additional finding is the nurse likely to obtain? Fatigue.

13.A client with a right ulnar fracture and cast placement reports an increase in arm
pain. Which action should the nurse take
next? Assess right radial pulse volume.



14.A client with type 2 diabetes mellitus arrives to the clinic reporting episodes of
weakness and palpitations. Which finding is most important for the nurse to
monitor? Excessive perspiration.

15.A client asks the nurse for information about how to reduce risk factors for
benign prostatic hyperplasia (BPH). Which information should the nurse
provide? Increase physical activity.




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, © lec_Bismark | Educational Resources4




16. In assessing a client with skin ulcers on the lower extremity, which findings
indicate that the ulcers are likely to be of venous, rather than arterial origin?
Irregular ulcer shapes and severe edema.

17. A family suspects that AIDS dementia is occurring in their adult child who is
HIV positive. Which symptom confirms the suspicion? A change has recently
occurred in handwriting.



18. Five months following treatment for herpes zoster, an older adult client tells the
home health nurse to continue to experience pain where the rash occurred. Which
action should the nurse implement? Complete an assessment of the client's pain.

19.A client who reports feeling chronically fatigued has a hemoglobin of 10 g/dL
(110 mmol/L). hematocrit of 34% (0.34 volume fraction), and microcytic and
hypochromic red blood cells (RBCs). Based on these findings, which dinner selection
should the nurse suggest to the client? Reference Range.

Hemoglobin (Hgb) [16 to 18 g/dL (160 to 180 g/L)] Hematocrit (Hct) [42% to

52% (0.42 to 0.52 volume fraction)] 9000

Beef steak with steamed broccoli and orange slices.




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