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MRO PRACTICE QUESTIONS & VERIFIED ANSWERS WITH COMPLETE SOLUTIONS | GRADED A+ | LATEST UPDATE 2026/2027

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MRO PRACTICE QUESTIONS & VERIFIED ANSWERS WITH COMPLETE SOLUTIONS | GRADED A+ | LATEST UPDATE 2026/2027

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19. All but which of the following are FDA approved for treatment of alcohol
dependence?
A.Naltrexone
B.Methadone
C.Acamprosate
D.Disulfiram


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B
Methadone has been long used for treatment of opiate and opioid
addiction. The other 3 drugs have been used to treat alcohol dependence.
Disulfiram was approved in 1949, followed by naltrexone in 1994 and
acamprosate in 2004.




81. All of the following are true for collection of an oral fluid specimen EXCEPT:
A.It is an observed collection
B.It generally takes approximately 2 minutes to collect an adequate specimen

,C.The specimen is placed in a buffer solution for transport to the laboratory
D.The donor must be observed and in a controlled environment for 15 minutes before
collection is begun
E.Two collection devices are needed for a "split specimen" collection


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D
The HHS Guidelines for Oral Fluid drug testing specify a 10 minute wait
period (the donor is under the observation and control of the collector)
before the collection of the specimen.


Section 8.1(d)(1) At this time, the collector starts the 10-minute wait period
and proceeds with the steps below before beginning the specimen
collection as described in Section 8.5.(2)




40. Laboratory initially determines the creatinine to be 1.5 mg/dL and the specific
gravity to be 1.0030. This would be reported to MRO as:
A.Negative - dilute
B.Adulterated
C.Substituted
D.Invalid


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D
Please see slide 10 of the Specimen Validity Testing presentation. This
includes a criterion of reporting inconsistent creatinine concentrations and
specific gravity. In this case the creatinine is less than 2.0 mg/dL and the
specific gravity 1.0030. These are inconsistent with each other and therefore
the specimen is reported as invalid by the lab - answer D




85. Which of the following would you expect to routinely detect in oral fluid after
smoking marijuana:

,A.THC
B.THCA at concentrations greater than 10 ng/ml
C.11-Hydroxy-THC
D.THCA at concentrations less than 1 ng/ml
E.THCA glucuronide


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A
See slide 6 of the Oral Fluid Laboratory Testing presentation. A good
discussion of the detection of THC and THCA detection in oral fluid can be
found in the preamble to the HHS Mandatory Guidelines (Effective
October 1, 2017) : Fed Registr; 2017,82 FR 7920.




13. A person who meets 3 criteria for Substance Use Disorder is categorized as which
of the following?
A.Mild
B.Moderate
C.Severe
D.Extreme


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A
The current definition of Substance Use Disorder comes from the American
Psychiatric Association's Diagnostic and Statistical Manual, 5th Edition
(DSM-V).




19a. Which of the following treatment modalities does not show positive benefits
compared to costs according to NORC CALDATA research?
A.Residential Inpatient
B.Outpatient Treatment
C.Social Model

, D.Methadone at Discharge
E.None of the Above


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E
Slide 9 on Tab 4.41 shows that A, B, C and D all show a positive benefit to
cost ratio. E is the correct answer.




79. Which of the following best approximates the elimination rate for alcohol from
blood:
A.0.18% w/v per hour
B.0.018% w/v per hour
C.0.005 % w/v per hour
D.0.025% w/v per hour


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B
Although the elimination rate can vary from 0.005 to 0.03 w/v per hour,
0.018 % w/v per hour is considered to be average elimination rate. See slide
2 of the Alcohol Testing and Toxicology presentation.




31. DOT makes collection under direct observation mandatory for all except which of
the following?
A.Evidence of tampering with the specimen
B.Previous specimen was negative dilute (Cr. >5 <20 and SG <1.0030)
C.Specimen temperature out of range
D.Invalid specimen with no medical explanation
E.Split specimen was not available for testing


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