Pharmacotherapeutics for
Advanced Practice Nurse
Prescribers with Davis Edge
6th Edition
• Author(s)Teri Moser Woo; Wendy
L. Wright
TEST BANK
▪ The Foundation
▪ Pharmacotherapeutics with Single Drugs
▪ Pharmacotherapeutics with Multiple Drugs
▪ Special Drug Treatment Considerations
,Question 1
An FNP is evaluating a 62-year-old man with newly diagnosed
hypertension. The patient asks whether he can simply start taking an
antihypertensive medication that worked well for his brother. Which
response by the APRN best reflects principles of safe prescribing?
A. Prescribing should primarily be based on family response because
medication effects are highly predictable among relatives.
B. Medication selection should be individualized using the patient's
diagnosis, comorbidities, concurrent medications, and risk factors
before choosing therapy.
C. The medication with the lowest cost should always be selected first
regardless of patient characteristics.
D. Prescribers should avoid discussing treatment options with patients
to prevent confusion.
Correct Answer: B
Rationale: Safe and effective prescribing requires an individualized
assessment that includes diagnosis, age, comorbidities, medication
history, allergies, organ function, potential interactions, and patient
preferences. Family response may occasionally provide useful
information, but it should not replace patient-specific assessment. Cost
is important but is only one factor in therapeutic decision-making.
Shared decision-making and patient education are essential
components of evidence-based prescribing.
,Question 2
A newly licensed APRN is beginning independent practice and is
reviewing strategies to reduce medication errors. Which action is most
appropriate before issuing a prescription?
A. Prescribe quickly to improve clinic efficiency and verify details later.
B. Confirm the indication, review allergies, reconcile current
medications, and verify that the benefits outweigh the risks.
C. Avoid discussing adverse effects because it may reduce adherence.
D. Prescribe brand-name medications whenever possible to minimize
confusion.
Correct Answer: B
Rationale: Medication reconciliation, allergy review, confirmation of
indication, and risk-benefit assessment are core elements of safe
prescribing. Efficiency should never supersede safety. Counseling
regarding adverse effects improves informed consent and often
enhances adherence. Brand-name medications are not inherently safer
than generic formulations.
Question 3
An AGPCNP is caring for an 84-year-old woman with chronic kidney
disease who requires initiation of a renally cleared medication. Which
prescribing principle is most appropriate?
A. Age alone determines dosing.
B. Serum creatinine within the laboratory reference range excludes
renal impairment.
, C. Drug dosing should consider estimated renal function because
reduced clearance may increase toxicity.
D. Older adults generally require higher doses because of reduced
absorption.
Correct Answer: C
Rationale: Renal function should be evaluated before prescribing
medications that are substantially renally eliminated. Older adults often
have reduced renal clearance despite apparently normal serum
creatinine due to decreased muscle mass. Dose adjustments or longer
dosing intervals may be required to prevent toxicity. Age alone does
not determine dosing, and higher doses are not routinely indicated.
Question 4
A patient receiving warfarin is prescribed trimethoprim-
sulfamethoxazole by an urgent care clinician. During follow-up, the
APRN recognizes this combination as an example of:
A. Therapeutic duplication.
B. A potentially significant drug-drug interaction requiring monitoring
or therapy modification.
C. Drug tolerance.
D. A pharmacogenomic contraindication.
Correct Answer: B
Rationale: Prescribers must assess potential drug-drug interactions
before initiating therapy. Trimethoprim-sulfamethoxazole can increase
warfarin effects and substantially raise bleeding risk. Therapeutic
duplication involves unnecessary use of medications from the same
Advanced Practice Nurse
Prescribers with Davis Edge
6th Edition
• Author(s)Teri Moser Woo; Wendy
L. Wright
TEST BANK
▪ The Foundation
▪ Pharmacotherapeutics with Single Drugs
▪ Pharmacotherapeutics with Multiple Drugs
▪ Special Drug Treatment Considerations
,Question 1
An FNP is evaluating a 62-year-old man with newly diagnosed
hypertension. The patient asks whether he can simply start taking an
antihypertensive medication that worked well for his brother. Which
response by the APRN best reflects principles of safe prescribing?
A. Prescribing should primarily be based on family response because
medication effects are highly predictable among relatives.
B. Medication selection should be individualized using the patient's
diagnosis, comorbidities, concurrent medications, and risk factors
before choosing therapy.
C. The medication with the lowest cost should always be selected first
regardless of patient characteristics.
D. Prescribers should avoid discussing treatment options with patients
to prevent confusion.
Correct Answer: B
Rationale: Safe and effective prescribing requires an individualized
assessment that includes diagnosis, age, comorbidities, medication
history, allergies, organ function, potential interactions, and patient
preferences. Family response may occasionally provide useful
information, but it should not replace patient-specific assessment. Cost
is important but is only one factor in therapeutic decision-making.
Shared decision-making and patient education are essential
components of evidence-based prescribing.
,Question 2
A newly licensed APRN is beginning independent practice and is
reviewing strategies to reduce medication errors. Which action is most
appropriate before issuing a prescription?
A. Prescribe quickly to improve clinic efficiency and verify details later.
B. Confirm the indication, review allergies, reconcile current
medications, and verify that the benefits outweigh the risks.
C. Avoid discussing adverse effects because it may reduce adherence.
D. Prescribe brand-name medications whenever possible to minimize
confusion.
Correct Answer: B
Rationale: Medication reconciliation, allergy review, confirmation of
indication, and risk-benefit assessment are core elements of safe
prescribing. Efficiency should never supersede safety. Counseling
regarding adverse effects improves informed consent and often
enhances adherence. Brand-name medications are not inherently safer
than generic formulations.
Question 3
An AGPCNP is caring for an 84-year-old woman with chronic kidney
disease who requires initiation of a renally cleared medication. Which
prescribing principle is most appropriate?
A. Age alone determines dosing.
B. Serum creatinine within the laboratory reference range excludes
renal impairment.
, C. Drug dosing should consider estimated renal function because
reduced clearance may increase toxicity.
D. Older adults generally require higher doses because of reduced
absorption.
Correct Answer: C
Rationale: Renal function should be evaluated before prescribing
medications that are substantially renally eliminated. Older adults often
have reduced renal clearance despite apparently normal serum
creatinine due to decreased muscle mass. Dose adjustments or longer
dosing intervals may be required to prevent toxicity. Age alone does
not determine dosing, and higher doses are not routinely indicated.
Question 4
A patient receiving warfarin is prescribed trimethoprim-
sulfamethoxazole by an urgent care clinician. During follow-up, the
APRN recognizes this combination as an example of:
A. Therapeutic duplication.
B. A potentially significant drug-drug interaction requiring monitoring
or therapy modification.
C. Drug tolerance.
D. A pharmacogenomic contraindication.
Correct Answer: B
Rationale: Prescribers must assess potential drug-drug interactions
before initiating therapy. Trimethoprim-sulfamethoxazole can increase
warfarin effects and substantially raise bleeding risk. Therapeutic
duplication involves unnecessary use of medications from the same
