PA PSYCHIATRY EXAM 5 2026 COMPLETE
STUDY GUIDE WITH DSM-5 CONDITIONS AND
CLINICAL CASE REVIEW
◉ Major depressive disorder.
Answer: Depressed Mood or Anhedonia
Dx: 5 or more of the SIGECAPS Sxs for *> 2 wks* effecting normal
function
Tx:
*SSRI* or *SNRI* > TCA/MAOi > ECT
◉ S/Es of SSRIs.
Answer: *Sexual Dysfunction*
Wt gain
Anxiety
Nausea
◉ *SHIVERS* of Serotonin Syndrome.
Answer: *S*hivering
,*H*yperreflexia
*I*ncreased temp (fever)
*V*itals, unstable
*E*ncephalopathy
*R*estless
*S*weating
Tx: Cyproheptadine
◉ 1st line Tx of depression in children.
Answer: Fluoxetine (Prozac)
- Longest Half-life of all SSRIs
- Caution ↑ SI in the 1st 2 weeks of use
◉ SSRI known to cause QT interval prolongation.
Answer: Citalopram (Celexa)
◉ Screening tool or questionnaire used in clinic for:
Bipolar Disorder
Major Depression Disorder.
Answer: BPD: The Mood Disorder Questionaire
,MDD: Beck Depression Inventory
◉ Atypical Antidepressant which inhibits DA reuptake, has less
sexual and wt-related side effects, but decreases *seizure* threshold.
Answer: Bupropion
*smoking cessation*
◉ *SNRI Trade Names*
Effexor
Pristiq
Cymbalta
Fetzima.
Answer: *SNRI Drug Names*
Venlafaxine
Desvenlafaxine
Duloxetine
Levomilnacipran
◉ TCA antidepressants
*special characteristics*.
Answer: Desipramine - selective NET inhibitor
, Imipramine - tx of enuresis
Amitriptyline- tx of neuromuscular pain
Nortriptyline
*QT Interval prolongation* = arrythmias
◉ MAO Inhibitors used as antidepressants
*T*ake *P*ride in *S*hanghai.
Answer: Tranylcypromine
Phenelzine
Selegiline
◉ Antidepressant which inhibits MAO b mechanisms and can ↑
dopamine concentrations.
Answer: Selegiline
- Can be added in Tx of Parkinson's
◉ Suicide Risk Assessment
*SAD PERSONS*
0-4 Low
5-6 Moderate
7-10 High.
STUDY GUIDE WITH DSM-5 CONDITIONS AND
CLINICAL CASE REVIEW
◉ Major depressive disorder.
Answer: Depressed Mood or Anhedonia
Dx: 5 or more of the SIGECAPS Sxs for *> 2 wks* effecting normal
function
Tx:
*SSRI* or *SNRI* > TCA/MAOi > ECT
◉ S/Es of SSRIs.
Answer: *Sexual Dysfunction*
Wt gain
Anxiety
Nausea
◉ *SHIVERS* of Serotonin Syndrome.
Answer: *S*hivering
,*H*yperreflexia
*I*ncreased temp (fever)
*V*itals, unstable
*E*ncephalopathy
*R*estless
*S*weating
Tx: Cyproheptadine
◉ 1st line Tx of depression in children.
Answer: Fluoxetine (Prozac)
- Longest Half-life of all SSRIs
- Caution ↑ SI in the 1st 2 weeks of use
◉ SSRI known to cause QT interval prolongation.
Answer: Citalopram (Celexa)
◉ Screening tool or questionnaire used in clinic for:
Bipolar Disorder
Major Depression Disorder.
Answer: BPD: The Mood Disorder Questionaire
,MDD: Beck Depression Inventory
◉ Atypical Antidepressant which inhibits DA reuptake, has less
sexual and wt-related side effects, but decreases *seizure* threshold.
Answer: Bupropion
*smoking cessation*
◉ *SNRI Trade Names*
Effexor
Pristiq
Cymbalta
Fetzima.
Answer: *SNRI Drug Names*
Venlafaxine
Desvenlafaxine
Duloxetine
Levomilnacipran
◉ TCA antidepressants
*special characteristics*.
Answer: Desipramine - selective NET inhibitor
, Imipramine - tx of enuresis
Amitriptyline- tx of neuromuscular pain
Nortriptyline
*QT Interval prolongation* = arrythmias
◉ MAO Inhibitors used as antidepressants
*T*ake *P*ride in *S*hanghai.
Answer: Tranylcypromine
Phenelzine
Selegiline
◉ Antidepressant which inhibits MAO b mechanisms and can ↑
dopamine concentrations.
Answer: Selegiline
- Can be added in Tx of Parkinson's
◉ Suicide Risk Assessment
*SAD PERSONS*
0-4 Low
5-6 Moderate
7-10 High.
