Oncology Exam 2 Group Questions with all Correct &
100% Verified Answers |Actual Complete Exam |Already
Graded A+
Which of the following is NOT a part of the multiple myeloma triad?
a. plasmacytosis (>10%)
b. lytic bone lesions
c. serum and or urine M component
d. lipid abnormalities ✔Correct Answer-d. Lipid abnormalities
Multiple myeloma evolves from _________ a premalignant state that is character by the
presence of monoclonal protein without bone marrow involvement or end organ damage.
✔Correct Answer-MGUS (monoclonal gammopathy of undetermined significance
Symptomatic myeloma is defined using the CRAB criteria. The CRAB criteria consists of
hypercalcemia, renal impairment, ___________, and bony symptoms ✔Correct Answer-
Anemia
NS is a 42 year old woman that was recently diagnosed with symptomatic multiple myeloma.
She is suffering from end organ damage, hypercalcemia, renal impairment, anemia, and bony
symptoms. Her lab work came back today and she has a serum beta-2 microglobulin of 6.1mg/L.
What stage is NS's multiple myeloma? ✔Correct Answer-Stage 3
PL is a 46 yo WF who presents to the clinic of increasing fatigue. She has normochromic,
normocytic anemia with a Hb of 9 g/dL. After further laboratory analysis she is diagnosed with
Stage III multiple myeloma. Two weeks later she comes back with a warm, tender, swollen right
lower leg. Since patients with multiple myeloma are prone to thrombotic events, name two
treatment options for supportive care of this issue. ✔Correct Answer-Aspirin, Warfarin or Low
Molecular Weight Heparin (any two out of these choices)
RA is a 63 year old man diagnosed with asymptomatic myeloma. What treatment regimen
would you recommend for RAs asymptomatic myeloma? ✔Correct Answer-a. NO therapy is
recommended at this time because RA is asymptomatic
LO was diagnosed with multiple myeloma after lab work revealed a serum beta-2
microglobulin of 6.3 mg/dL. She will begin induction therapy tomorrow. Her drug
regimen should include which medications (select all that apply)
a. An alkylating agent like Melphalan
b. An anthracycline like Doxorubicin
c. Vincristine
d. High Dose Steroids ✔Correct Answer-All of them
,After a patient with multiple myeloma has finished induction and consolidation
therapy a stem cell transplant is required. What type of stem cell transplant is
recommended ✔Correct Answer-Autologus
Acute lymphoblastic leukemia (ALL) accounts for 75% of all childhood leukemias.
Children with __________ are at an increased risk for B-cell ALL and children with
_________ are at an increased risk for T cell ALL
a. Down Syndrome; Ataxia-telangiectasia
b. Down Syndrome; Turner Syndrome
c. Turner Syndrome; Cystic Fibrosis
d. Cystic Fibrosis; Ataxia-telangiectasia ✔Correct Answer-A. Down Syndrome; Ataxia-
telangiectasia
Acute lymphoblastic leukemia (ALL) features chromosomal translocations, deletions,
and amplifications. The best known molecular mechanism, occurring in up to 20% of
all ALL cases is _____________. ✔Correct Answer-Philadelphia Chromosome (Bcr-Abl fusion
protein)
RA has completed both induction and consolidation phase treatment for acute
lymphoblastic leukemia. He is now ready to begin maintenance therapy with 6-mercaptopurine,
Methotrexate, Vincristine, and steroids intrathecally. How long will
RA need to continue maintenance therapy? ✔Correct Answer-2 to 3 years
The ____________ regimen developed by MD Anderson is often used in the treatment of
ALL. This regimen uses small doses more frequently of a variety of
chemotherapeutics ✔Correct Answer-hyperCVAD
__________ is a neoplastic disease characterized by painless, progressive enlargement of
lymph nodes, spleen, and other lymphoid tissues resulting in proliferation of lymphocytes,
histiocytes, eosinophils, and Reed Sternberg cells in a background of inflammatory cells
✔Correct Answer-Hodgkin's Lymphoma
All of the following are signs and symptoms of hodgkin's lymphoma except
a. non tender asymmetrical enlargement of superficial lymph nodes
b. Neck vein engogement
c. Enlarged spleen
d. Persistent hyperglycemia ✔Correct Answer-d. Persistent hyperglycemia
. The development of Hodgkin lymphoma has been linked to which of the following
infections (select all that apply):
a. Epstein Barr Virus
b. HIV
c. Influenza virus
, d. mononucleosis ✔Correct Answer-a. Epstein Barr Virus
b. HIV
d. mononucleosis
HL is a 34 year old female that presented to her primary care physician because she
noticed a mass on the right side of her neck that has been growing for the past 2 months. She
was diagnosed with stage I Hodgkin Lymphoma . What therapy would you recommend for
her treatment? ✔Correct Answer-Radiation therapy
ZI was diagnosed with stage 3 Hodgkin's lymphoma after he noticed a large growth on
the left side of his neck last week. Today he is supposed to start cyclical chemotherapy. His
regimen is known as the ABVD regimen . Select the four drugs that make up the ABVD
regimen
a. Doxorubicin
b. Bleomycin
c. Vinblastine
d. Dacarbazine ✔Correct Answer-all of them
The Hodgkin and Reed-Sternberg cells are mostly multinucleated, giant cells, derived
from mutation in ________________. ✔Correct Answer-T-lymphocytes
Approximately 3-5% of all breast cancers are medullary carcinoma. Medullary
carcinomas are most common in patients with the BRCA1 mutations . Which of the
following correctly characterizes medullary carcinomas
a. ER positive, PR positive, Her2 positive
b. ER positive, PR positive, Her2 negative
c. ER positive, PR negative, Her2 negative
d. ER negative, PR negative, Her2 negative ✔Correct Answer-d. ER negative, PR negative, Her2
negative
True or False: Regarding the choice of surgery, lumpectomy followed by radiation
therapy with breast cancer is equivalent to mastectomy . ✔Correct Answer-True
There are currently two gene assays that are used in clinical practice to determine
risk of recurrence and aid the decision on adjuvant chemotherapy in patients. One of
these assays is the Oncotype Dx. What is the name of the other assay? ✔Correct Answer-
mammaPrint
Select the three most validated markers for breast cancer
a. Estrogen Receptor
b. Progesterone Receptor
c. Her2/ErB2
d. Testosterone Receptor ✔Correct Answer-a. Estrogen Receptor
b. Progesterone Receptor
100% Verified Answers |Actual Complete Exam |Already
Graded A+
Which of the following is NOT a part of the multiple myeloma triad?
a. plasmacytosis (>10%)
b. lytic bone lesions
c. serum and or urine M component
d. lipid abnormalities ✔Correct Answer-d. Lipid abnormalities
Multiple myeloma evolves from _________ a premalignant state that is character by the
presence of monoclonal protein without bone marrow involvement or end organ damage.
✔Correct Answer-MGUS (monoclonal gammopathy of undetermined significance
Symptomatic myeloma is defined using the CRAB criteria. The CRAB criteria consists of
hypercalcemia, renal impairment, ___________, and bony symptoms ✔Correct Answer-
Anemia
NS is a 42 year old woman that was recently diagnosed with symptomatic multiple myeloma.
She is suffering from end organ damage, hypercalcemia, renal impairment, anemia, and bony
symptoms. Her lab work came back today and she has a serum beta-2 microglobulin of 6.1mg/L.
What stage is NS's multiple myeloma? ✔Correct Answer-Stage 3
PL is a 46 yo WF who presents to the clinic of increasing fatigue. She has normochromic,
normocytic anemia with a Hb of 9 g/dL. After further laboratory analysis she is diagnosed with
Stage III multiple myeloma. Two weeks later she comes back with a warm, tender, swollen right
lower leg. Since patients with multiple myeloma are prone to thrombotic events, name two
treatment options for supportive care of this issue. ✔Correct Answer-Aspirin, Warfarin or Low
Molecular Weight Heparin (any two out of these choices)
RA is a 63 year old man diagnosed with asymptomatic myeloma. What treatment regimen
would you recommend for RAs asymptomatic myeloma? ✔Correct Answer-a. NO therapy is
recommended at this time because RA is asymptomatic
LO was diagnosed with multiple myeloma after lab work revealed a serum beta-2
microglobulin of 6.3 mg/dL. She will begin induction therapy tomorrow. Her drug
regimen should include which medications (select all that apply)
a. An alkylating agent like Melphalan
b. An anthracycline like Doxorubicin
c. Vincristine
d. High Dose Steroids ✔Correct Answer-All of them
,After a patient with multiple myeloma has finished induction and consolidation
therapy a stem cell transplant is required. What type of stem cell transplant is
recommended ✔Correct Answer-Autologus
Acute lymphoblastic leukemia (ALL) accounts for 75% of all childhood leukemias.
Children with __________ are at an increased risk for B-cell ALL and children with
_________ are at an increased risk for T cell ALL
a. Down Syndrome; Ataxia-telangiectasia
b. Down Syndrome; Turner Syndrome
c. Turner Syndrome; Cystic Fibrosis
d. Cystic Fibrosis; Ataxia-telangiectasia ✔Correct Answer-A. Down Syndrome; Ataxia-
telangiectasia
Acute lymphoblastic leukemia (ALL) features chromosomal translocations, deletions,
and amplifications. The best known molecular mechanism, occurring in up to 20% of
all ALL cases is _____________. ✔Correct Answer-Philadelphia Chromosome (Bcr-Abl fusion
protein)
RA has completed both induction and consolidation phase treatment for acute
lymphoblastic leukemia. He is now ready to begin maintenance therapy with 6-mercaptopurine,
Methotrexate, Vincristine, and steroids intrathecally. How long will
RA need to continue maintenance therapy? ✔Correct Answer-2 to 3 years
The ____________ regimen developed by MD Anderson is often used in the treatment of
ALL. This regimen uses small doses more frequently of a variety of
chemotherapeutics ✔Correct Answer-hyperCVAD
__________ is a neoplastic disease characterized by painless, progressive enlargement of
lymph nodes, spleen, and other lymphoid tissues resulting in proliferation of lymphocytes,
histiocytes, eosinophils, and Reed Sternberg cells in a background of inflammatory cells
✔Correct Answer-Hodgkin's Lymphoma
All of the following are signs and symptoms of hodgkin's lymphoma except
a. non tender asymmetrical enlargement of superficial lymph nodes
b. Neck vein engogement
c. Enlarged spleen
d. Persistent hyperglycemia ✔Correct Answer-d. Persistent hyperglycemia
. The development of Hodgkin lymphoma has been linked to which of the following
infections (select all that apply):
a. Epstein Barr Virus
b. HIV
c. Influenza virus
, d. mononucleosis ✔Correct Answer-a. Epstein Barr Virus
b. HIV
d. mononucleosis
HL is a 34 year old female that presented to her primary care physician because she
noticed a mass on the right side of her neck that has been growing for the past 2 months. She
was diagnosed with stage I Hodgkin Lymphoma . What therapy would you recommend for
her treatment? ✔Correct Answer-Radiation therapy
ZI was diagnosed with stage 3 Hodgkin's lymphoma after he noticed a large growth on
the left side of his neck last week. Today he is supposed to start cyclical chemotherapy. His
regimen is known as the ABVD regimen . Select the four drugs that make up the ABVD
regimen
a. Doxorubicin
b. Bleomycin
c. Vinblastine
d. Dacarbazine ✔Correct Answer-all of them
The Hodgkin and Reed-Sternberg cells are mostly multinucleated, giant cells, derived
from mutation in ________________. ✔Correct Answer-T-lymphocytes
Approximately 3-5% of all breast cancers are medullary carcinoma. Medullary
carcinomas are most common in patients with the BRCA1 mutations . Which of the
following correctly characterizes medullary carcinomas
a. ER positive, PR positive, Her2 positive
b. ER positive, PR positive, Her2 negative
c. ER positive, PR negative, Her2 negative
d. ER negative, PR negative, Her2 negative ✔Correct Answer-d. ER negative, PR negative, Her2
negative
True or False: Regarding the choice of surgery, lumpectomy followed by radiation
therapy with breast cancer is equivalent to mastectomy . ✔Correct Answer-True
There are currently two gene assays that are used in clinical practice to determine
risk of recurrence and aid the decision on adjuvant chemotherapy in patients. One of
these assays is the Oncotype Dx. What is the name of the other assay? ✔Correct Answer-
mammaPrint
Select the three most validated markers for breast cancer
a. Estrogen Receptor
b. Progesterone Receptor
c. Her2/ErB2
d. Testosterone Receptor ✔Correct Answer-a. Estrogen Receptor
b. Progesterone Receptor
