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Exam (elaborations)

NUR 376 Pathophysiology Exam 1 Questions With Complete Solutions

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NUR 376 Pathophysiology Exam 1 Questions With Complete Solutions

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NUR 376 Pathophysiology Exam 1
Questions With Complete Solutions

Brian, age 28, began an aerobic exercise program 2 years ago. Brian now
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competes in long-distance cycling events and considers himself to be an
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endurance athlete who is in the "best shape of his life." An
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echocardiogram reveals a slightly enlarged left ventricle. What cellular
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change or injury that is best exemplified by the case scenario. -
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CORRECT ANSWER✔✔-Physiologic hypertrophy
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An ADAPTIVE type of hypertrophy that occurs due to extensive exercise,
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whereby the heart will create new blood vessel branches (angiogenesis)
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and there is increased mitochondria, ATP, and actin/myosin filaments in
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the muscle.
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Recently, Karen learned that not only does HIV directly attack CD4 cells,
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but the presence of the virus seems to activate pathways responsible
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for programmed cell death in CD4 cells. Thus, HIV infection appears to
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increase the rate of "suicide" for CD4 cells. - CORRECT ANSWER✔✔-
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Apoptosis


Define dysplasia - CORRECT ANSWER✔✔-Compared to normal cells,
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cells demonstrating dysplasia are atypical in size and shape. Dysplasia
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,does not mean the cells are cancerous. However, some screening tests,
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such as the Pap smear, examine tissues to determine if any cellular
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changes are taking place. Any changes in the cells can then be
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monitored over time. | |




A biopsy of a skin lesion is conducted on Leann, a 48-year-old woman.
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Biopsy results revealed proliferating cells that were well-differentiated
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and resembled surrounding cells. The cells were contained within a
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well-defined area. - CORRECT ANSWER✔✔-Benign neoplasia. | | | | |




Neoplasia is uncontrolled and unregulated cell growth. The mass of
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tissue resulting is known as a "neoplasm." In a benign neoplasm, the
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cells do not have the characteristics associated with malignancy. The
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cells, although cancerous, are well-differentiated, meaning they
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resemble normal, mature cells. The cells are also in a contained area
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and are unlikely to spread.
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Miguel, a retired warehouse supervisor, had a myocardial infarction.
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Further evaluation revealed he had significant blockage in his left
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descending coronary artery. The blockage resulted in ischemia and cell
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death for those cells served by the artery. - CORRECT ANSWER✔✔-
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Necrosis


Necrosis is premature cell death caused by cell injury. Necrosis differs
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from apoptosis, in that the cellular destruction results from some form
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, of trauma, rather than genetic programming. May lead to GANGRENE
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which is when dead tissue houses bacteria.
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Julianne, who suffers from familial hypercholesterolemia, presents with
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xanthomas. Xanthomas are excess cholesterol deposits, which appear as
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|yellow skin lesions. What cell process is this - CORRECT ANSWER✔✔-
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Intracellular accumulation. |




Some disease processes stimulate intracellular accumulations of
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particles, such as calcium, cholesterol, and triglycerides, glucose, among
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other substances. In familial hypercholesterolemia, a genetic defect
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causes decreased cellular uptake of cholesterol, resulting in high serum
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cholesterol levels. Cholesterol deposits, known as xanthomas, may
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appear to form under the skin.
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Janae experienced a frightening ATV accident, in which her ATV flipped
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over and she ended up catching a portion of her upper arm on a barbed
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wire fence. Although Janae's injuries healed fully, enlarged, keloid scar
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formations remain at the injury site. - CORRECT ANSWER✔✔-
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Hyperplasia


cell proliferation, known as hyperplasia, was stimulated as a result of
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her injury. A keloid results from overgrowth of granulation tissue during
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the wound repair process.
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