HESI A2 Entrance 2026/2027 Exam Practice
Questions WITH VERIFIED ANSWERS
WITH RATIONALES
Question 1
A nurse is teaching a group of students about the function of red blood cells. Which statement is
correct?
A. Red blood cells produce antibodies.
B. Red blood cells transport oxygen throughout the body.
C. Red blood cells fight bacterial infections.
D. Red blood cells form blood clots.
Correct Answer: B. Red blood cells transport oxygen throughout the body.
Rationale: Red blood cells contain hemoglobin, which binds oxygen in the lungs and delivers it
to body tissues.
Question 2
Which organ is primarily responsible for removing nitrogenous waste from the blood?
A. Liver
B. Heart
C. Kidney
D. Pancreas
Correct Answer: C. Kidney.
Rationale: The kidneys filter blood, remove waste products, regulate electrolyte balance, and
produce urine.
Question 3
Which blood vessel carries oxygenated blood from the lungs to the heart?
,A. Pulmonary artery
B. Aorta
C. Pulmonary vein
D. Superior vena cava
Correct Answer: C. Pulmonary vein.
Rationale: The pulmonary veins transport oxygen-rich blood from the lungs to the left atrium.
Question 4
Which chamber of the heart pumps blood into the systemic circulation?
A. Right atrium
B. Right ventricle
C. Left atrium
D. Left ventricle
Correct Answer: D. Left ventricle.
Rationale: The left ventricle pumps oxygenated blood into the aorta for circulation throughout
the body.
Question 5
Which structure is the functional unit of the kidney?
A. Neuron
B. Nephron
C. Alveolus
D. Villus
Correct Answer: B. Nephron.
Rationale: Nephrons filter blood and regulate water, electrolytes, and waste removal.
Question 6
Which vitamin is essential for calcium absorption?
, A. Vitamin A
B. Vitamin B12
C. Vitamin C
D. Vitamin D
Correct Answer: D. Vitamin D.
Rationale: Vitamin D promotes calcium absorption from the gastrointestinal tract, supporting
healthy bones.
Question 7
Which organ stores bile produced by the liver?
A. Stomach
B. Pancreas
C. Gallbladder
D. Spleen
Correct Answer: C. Gallbladder.
Rationale: The gallbladder stores and concentrates bile until it is needed for fat digestion.
Question 8
Which blood type is considered the universal recipient?
A. O-
B. A+
C. AB+
D. B-
Correct Answer: C. AB+.
Rationale: Individuals with AB-positive blood can receive red blood cells from all ABO and Rh
blood types.
Question 9
Which body system is responsible for producing hormones?
A. Respiratory system
B. Endocrine system
Questions WITH VERIFIED ANSWERS
WITH RATIONALES
Question 1
A nurse is teaching a group of students about the function of red blood cells. Which statement is
correct?
A. Red blood cells produce antibodies.
B. Red blood cells transport oxygen throughout the body.
C. Red blood cells fight bacterial infections.
D. Red blood cells form blood clots.
Correct Answer: B. Red blood cells transport oxygen throughout the body.
Rationale: Red blood cells contain hemoglobin, which binds oxygen in the lungs and delivers it
to body tissues.
Question 2
Which organ is primarily responsible for removing nitrogenous waste from the blood?
A. Liver
B. Heart
C. Kidney
D. Pancreas
Correct Answer: C. Kidney.
Rationale: The kidneys filter blood, remove waste products, regulate electrolyte balance, and
produce urine.
Question 3
Which blood vessel carries oxygenated blood from the lungs to the heart?
,A. Pulmonary artery
B. Aorta
C. Pulmonary vein
D. Superior vena cava
Correct Answer: C. Pulmonary vein.
Rationale: The pulmonary veins transport oxygen-rich blood from the lungs to the left atrium.
Question 4
Which chamber of the heart pumps blood into the systemic circulation?
A. Right atrium
B. Right ventricle
C. Left atrium
D. Left ventricle
Correct Answer: D. Left ventricle.
Rationale: The left ventricle pumps oxygenated blood into the aorta for circulation throughout
the body.
Question 5
Which structure is the functional unit of the kidney?
A. Neuron
B. Nephron
C. Alveolus
D. Villus
Correct Answer: B. Nephron.
Rationale: Nephrons filter blood and regulate water, electrolytes, and waste removal.
Question 6
Which vitamin is essential for calcium absorption?
, A. Vitamin A
B. Vitamin B12
C. Vitamin C
D. Vitamin D
Correct Answer: D. Vitamin D.
Rationale: Vitamin D promotes calcium absorption from the gastrointestinal tract, supporting
healthy bones.
Question 7
Which organ stores bile produced by the liver?
A. Stomach
B. Pancreas
C. Gallbladder
D. Spleen
Correct Answer: C. Gallbladder.
Rationale: The gallbladder stores and concentrates bile until it is needed for fat digestion.
Question 8
Which blood type is considered the universal recipient?
A. O-
B. A+
C. AB+
D. B-
Correct Answer: C. AB+.
Rationale: Individuals with AB-positive blood can receive red blood cells from all ABO and Rh
blood types.
Question 9
Which body system is responsible for producing hormones?
A. Respiratory system
B. Endocrine system
