Adv Pharm Ch 18 Exam #1 Questions with correct
answers
When given subcutaneously, how long until neutral protamine Hagedorn (NPH)
insulin begins to take effect (onset of action) after administration?
1. Fifteen to thirty minutes
2. Sixty to ninety minutes
3. Three to four hours
4. Six to eight hours - ✔✔2. Sixty to ninety minutes
Hypoglycemia can result from the action of either insulin or an oral hypoglycemic.
Signs and symptoms of hypoglycemia include:
1. "Fruity" breath odor and rapid respiration
2. Diarrhea, abdominal pain, weight loss, and hypertension
3. Dizziness, confusion, diaphoresis, and tachycardia
4. Easy bruising, palpitations, cardiac dysrhythmias, and coma - ✔✔3. Dizziness,
confusion, diaphoresis, and tachycardia
Nonselective beta blockers and alcohol create serious drug interactions with
insulin because they:
1. Increase blood glucose levels
2. Produce unexplained diaphoresis
3. Interfere with the ability of the body to metabolize glucose
4. Mask the signs and symptoms of altered glucose levels - ✔✔4. Mask the signs
and symptoms of altered glucose levels
, Lispro is an insulin analogue produced by recombinant DNA technology. Which of
the following statements about this form of insulin is NOT true?
1. Optimal time of preprandial injection is 15 minutes.
2. Duration of action is increased when the dose is increased.
3. It is compatible with NPH insulin.
4. It has no pronounced peak. - ✔✔2. Duration of action is increased when the
dose is increased.
The decision may be made to switch from twice daily NPH insulin to insulin
glargine to improve glycemia control throughout the day. If this is done:
1. The initial dose of glargine is reduced by 20% to avoid hypoglycemia.
2. The initial dose of glargine is 2 to 10 units per day.
3. Patients who have been on high doses of NPH will need tests for insulin
antibodies.
4. Obese patients may require more than 100 units per day. - ✔✔1. The initial
dose of glargine is reduced by 20% to avoid hypoglycemia.
When blood glucose levels are difficult to control in type 2 diabetes, some form of
insulin may be added to the treatment regimen to control blood glucose and limit
complication risks. Which of the following statements is accurate based on
research?
1. Premixed insulin analogues are better at lowering HbA1C and have less risk for
hypoglycemia.
2. Premixed insulin analogues and the newer premixed insulins are associated
with
more weight gain than the oral antidiabetic agents.
answers
When given subcutaneously, how long until neutral protamine Hagedorn (NPH)
insulin begins to take effect (onset of action) after administration?
1. Fifteen to thirty minutes
2. Sixty to ninety minutes
3. Three to four hours
4. Six to eight hours - ✔✔2. Sixty to ninety minutes
Hypoglycemia can result from the action of either insulin or an oral hypoglycemic.
Signs and symptoms of hypoglycemia include:
1. "Fruity" breath odor and rapid respiration
2. Diarrhea, abdominal pain, weight loss, and hypertension
3. Dizziness, confusion, diaphoresis, and tachycardia
4. Easy bruising, palpitations, cardiac dysrhythmias, and coma - ✔✔3. Dizziness,
confusion, diaphoresis, and tachycardia
Nonselective beta blockers and alcohol create serious drug interactions with
insulin because they:
1. Increase blood glucose levels
2. Produce unexplained diaphoresis
3. Interfere with the ability of the body to metabolize glucose
4. Mask the signs and symptoms of altered glucose levels - ✔✔4. Mask the signs
and symptoms of altered glucose levels
, Lispro is an insulin analogue produced by recombinant DNA technology. Which of
the following statements about this form of insulin is NOT true?
1. Optimal time of preprandial injection is 15 minutes.
2. Duration of action is increased when the dose is increased.
3. It is compatible with NPH insulin.
4. It has no pronounced peak. - ✔✔2. Duration of action is increased when the
dose is increased.
The decision may be made to switch from twice daily NPH insulin to insulin
glargine to improve glycemia control throughout the day. If this is done:
1. The initial dose of glargine is reduced by 20% to avoid hypoglycemia.
2. The initial dose of glargine is 2 to 10 units per day.
3. Patients who have been on high doses of NPH will need tests for insulin
antibodies.
4. Obese patients may require more than 100 units per day. - ✔✔1. The initial
dose of glargine is reduced by 20% to avoid hypoglycemia.
When blood glucose levels are difficult to control in type 2 diabetes, some form of
insulin may be added to the treatment regimen to control blood glucose and limit
complication risks. Which of the following statements is accurate based on
research?
1. Premixed insulin analogues are better at lowering HbA1C and have less risk for
hypoglycemia.
2. Premixed insulin analogues and the newer premixed insulins are associated
with
more weight gain than the oral antidiabetic agents.
