NCLEX-RN Practice Questions 2026-2027:
200 Medical-Surgical Nursing Exam
Questions with Rationales | Comprehensive
Nursing Test Bank for Students & Educators
Description:
Download the ultimate NCLEX-RN practice test bank 2026 with 200 evidence-based nursing
questions, detailed rationales, and updated clinical guidelines. Master medical-surgical nursing,
pharmacology, maternity, and psychiatric nursing. Perfect for nursing students, educators,
and exam prep. Ace your nursing exams with this complete study resource. Get your 2026/2027
nursing test bank today!
, NCLEX-RN Practice Questions 2026 | Nursing Test Bank with
Answers
SECTION A: ONCOLOGY AND HEMATOLOGY
Question 1
A nurse is providing nutrition education to a client with neutropenia. Which instruction should
the nurse prioritize to minimize infection risk?
A) Encourage consumption of fresh fruits and vegetables for vitamin C
B) Recommend avoidance of undercooked meat, fish, and eggs
C) Suggest adding pepper and paprika to enhance food flavor
D) Advise consuming raw sprouts for nutritional value
Answer: B
Explanation: Clients with neutropenia have compromised immune function and are at
significant risk for bacterial infections. The neutropenic diet emphasizes avoiding foods that may
harbor bacteria, including undercooked meat, fish, eggs, and unpasteurized products. Fresh fruits
and vegetables must be thoroughly washed or cooked; raw sprouts should be avoided entirely.
Spices such as pepper and paprika should be restricted as they may contain bacterial spores. The
primary goal is to prevent foodborne illnesses that could lead to life-threatening sepsis in
immunocompromised patients.
Question 2
A client receiving chemotherapy reports severe nausea and vomiting. Which intervention should
the nurse implement first?
A) Administer prescribed antiemetic medication
B) Encourage small, frequent meals throughout the day
C) Assess for signs of dehydration and electrolyte imbalance
D) Instruct the client to avoid food odors during meals
,Answer: C
Explanation: While all interventions are appropriate for managing chemotherapy-induced
nausea, assessment should precede intervention. The nurse must first evaluate the client's
hydration status and electrolyte balance to prevent complications such as acute kidney injury or
cardiac arrhythmias. Antiemetics should be administered as prescribed, but baseline assessment
ensures safe and effective care. Client teaching regarding dietary modifications and
environmental triggers is important but secondary to immediate physiological assessment.
Question 3
The nurse is teaching a client about the ABCDE method for melanoma screening. Which
characteristic indicates a concerning mole that requires immediate evaluation?
A) Symmetrical shape with uniform coloration
B) Border irregularity with color variation
C) Diameter smaller than 6 millimeters
D) Stable appearance over several months
Answer: B
Explanation: The ABCDE mnemonic is essential for melanoma detection: Asymmetry, Border
irregularity, Color variation, Diameter greater than 6mm, and Evolution or change over time.
Border irregularity with multiple colors within a single lesion is particularly concerning. Normal
moles are typically symmetrical, have regular borders, uniform color, and remain stable in
appearance. Any change in size, shape, or color requires prompt dermatological evaluation for
potential malignancy.
Question 4
The nurse is providing discharge teaching to a client with melanoma who will receive targeted
therapy with vemurafenib. Which statement indicates the client understands the treatment plan?
A) "This medication works by boosting my immune system to fight cancer"
B) "I will need to take this medication only during radiation therapy"
, C) "Vemurafenib targets specific genetic mutations in my cancer cells"
D) "This therapy completely eliminates the need for surgical intervention"
Answer: C
Explanation: Vemurafenib is a targeted therapy that specifically inhibits the BRAF V600E
mutation present in approximately 50% of melanomas. Unlike traditional chemotherapy, targeted
therapies attack specific molecular pathways in cancer cells. These medications do not rely on
immune system activation, are not limited to radiation therapy, and rarely replace surgical
intervention for primary lesions. Understanding the mechanism of targeted therapy helps clients
adhere to treatment regimens and maintain realistic expectations.
Question 5
A 65-year-old client is scheduled to receive recommended immunizations. Which vaccines
should the nurse administer?
A) Influenza and pneumococcal vaccines only
B) Influenza, pneumococcal, and herpes zoster vaccines
C) Influenza, pneumococcal, and hepatitis B vaccines
D) All routine adult vaccinations regardless of age
Answer: B
Explanation: The Centers for Disease Control and Prevention recommends that adults aged 65
years and older receive influenza vaccine annually, pneumococcal vaccine (both PCV15/20 and
PPSV23 depending on previous vaccination history), and herpes zoster vaccine (Shingrix) in two
doses. These immunizations address the increased susceptibility to respiratory infections and
herpes zoster reactivation in the aging population. Vaccination status should be assessed and
updated during routine health maintenance visits.
200 Medical-Surgical Nursing Exam
Questions with Rationales | Comprehensive
Nursing Test Bank for Students & Educators
Description:
Download the ultimate NCLEX-RN practice test bank 2026 with 200 evidence-based nursing
questions, detailed rationales, and updated clinical guidelines. Master medical-surgical nursing,
pharmacology, maternity, and psychiatric nursing. Perfect for nursing students, educators,
and exam prep. Ace your nursing exams with this complete study resource. Get your 2026/2027
nursing test bank today!
, NCLEX-RN Practice Questions 2026 | Nursing Test Bank with
Answers
SECTION A: ONCOLOGY AND HEMATOLOGY
Question 1
A nurse is providing nutrition education to a client with neutropenia. Which instruction should
the nurse prioritize to minimize infection risk?
A) Encourage consumption of fresh fruits and vegetables for vitamin C
B) Recommend avoidance of undercooked meat, fish, and eggs
C) Suggest adding pepper and paprika to enhance food flavor
D) Advise consuming raw sprouts for nutritional value
Answer: B
Explanation: Clients with neutropenia have compromised immune function and are at
significant risk for bacterial infections. The neutropenic diet emphasizes avoiding foods that may
harbor bacteria, including undercooked meat, fish, eggs, and unpasteurized products. Fresh fruits
and vegetables must be thoroughly washed or cooked; raw sprouts should be avoided entirely.
Spices such as pepper and paprika should be restricted as they may contain bacterial spores. The
primary goal is to prevent foodborne illnesses that could lead to life-threatening sepsis in
immunocompromised patients.
Question 2
A client receiving chemotherapy reports severe nausea and vomiting. Which intervention should
the nurse implement first?
A) Administer prescribed antiemetic medication
B) Encourage small, frequent meals throughout the day
C) Assess for signs of dehydration and electrolyte imbalance
D) Instruct the client to avoid food odors during meals
,Answer: C
Explanation: While all interventions are appropriate for managing chemotherapy-induced
nausea, assessment should precede intervention. The nurse must first evaluate the client's
hydration status and electrolyte balance to prevent complications such as acute kidney injury or
cardiac arrhythmias. Antiemetics should be administered as prescribed, but baseline assessment
ensures safe and effective care. Client teaching regarding dietary modifications and
environmental triggers is important but secondary to immediate physiological assessment.
Question 3
The nurse is teaching a client about the ABCDE method for melanoma screening. Which
characteristic indicates a concerning mole that requires immediate evaluation?
A) Symmetrical shape with uniform coloration
B) Border irregularity with color variation
C) Diameter smaller than 6 millimeters
D) Stable appearance over several months
Answer: B
Explanation: The ABCDE mnemonic is essential for melanoma detection: Asymmetry, Border
irregularity, Color variation, Diameter greater than 6mm, and Evolution or change over time.
Border irregularity with multiple colors within a single lesion is particularly concerning. Normal
moles are typically symmetrical, have regular borders, uniform color, and remain stable in
appearance. Any change in size, shape, or color requires prompt dermatological evaluation for
potential malignancy.
Question 4
The nurse is providing discharge teaching to a client with melanoma who will receive targeted
therapy with vemurafenib. Which statement indicates the client understands the treatment plan?
A) "This medication works by boosting my immune system to fight cancer"
B) "I will need to take this medication only during radiation therapy"
, C) "Vemurafenib targets specific genetic mutations in my cancer cells"
D) "This therapy completely eliminates the need for surgical intervention"
Answer: C
Explanation: Vemurafenib is a targeted therapy that specifically inhibits the BRAF V600E
mutation present in approximately 50% of melanomas. Unlike traditional chemotherapy, targeted
therapies attack specific molecular pathways in cancer cells. These medications do not rely on
immune system activation, are not limited to radiation therapy, and rarely replace surgical
intervention for primary lesions. Understanding the mechanism of targeted therapy helps clients
adhere to treatment regimens and maintain realistic expectations.
Question 5
A 65-year-old client is scheduled to receive recommended immunizations. Which vaccines
should the nurse administer?
A) Influenza and pneumococcal vaccines only
B) Influenza, pneumococcal, and herpes zoster vaccines
C) Influenza, pneumococcal, and hepatitis B vaccines
D) All routine adult vaccinations regardless of age
Answer: B
Explanation: The Centers for Disease Control and Prevention recommends that adults aged 65
years and older receive influenza vaccine annually, pneumococcal vaccine (both PCV15/20 and
PPSV23 depending on previous vaccination history), and herpes zoster vaccine (Shingrix) in two
doses. These immunizations address the increased susceptibility to respiratory infections and
herpes zoster reactivation in the aging population. Vaccination status should be assessed and
updated during routine health maintenance visits.
