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Usmle Step 1 First Aid Rapid Review - Classic_Relevant Treatments Questions With Correct Answers

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USMLE STEP 1 FIRST AID RAPID REVIEW - CLASSIC_RELEVANT TREATMENTS QUESTIONS WITH CORRECT ANSWERS

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Ampicillin / Amoxicillin


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Same MOA as penicillin, also can be combined with calvulanic acid to
protect against b-lactamase,

amOxicillin has greater Oral bioavailability

Use: gram+ bacteria, gram- rods, UTIs, neonatal infections
- "HEELPSS" = H. influ, E coli, Enterococcus, Listeria, Proteus mirabilis,
Salmonella, Shigella

Toxicity: Hypersensitivity reactions, ampicillin rash, pseudomembranous
colitis

Resistance: beta lactamases cleave beta lactam ring

,CMV


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Ganciclovir




Flutamide MOA


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Androgen recptor competitive antagonist
(FA 597)




Prophylaxis for endocarditis w/ surgical / dental procedure


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Penicillin. amoxecillin




B12 deficiency


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Vitamin B12 supplementation (work up cause w/ Schilling test)

,Legionella pneumophila


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Erythromycin




Class 1


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Class 1A: "the Queen Proclaims Diso'sPyramid" : Quinidine Procainamide
Disopyramide ↑ AP, QT


Class 1B " by placing a Mexi Lid in it" Mexiletine Lidocaine ↓ AP, no ∆ Vmax

Class 1C "Fries Please" Flecainide Propafenone x Na ch , min effect on AP




Influenza


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Rimantidine, oseltamivir




Prostate cancer/uterine fibroids


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, Leuprolide, GnRH (continuous)




Terbinafine MOA


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Terbinafine: Inhibits squalene epoxidase (inhibits lanosterol synthesis)
Hepatotoxic

4 fungal infections




Macrolids


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X s50 -> X translation
azithromycin, clarithromycin, erythromycin
• 4: "PUS" Pneumonia : atypical: Legionella, mycoplasma, Chlamydia), URTI (
group A strp), STD




Leuprolide MOA


Give this one a try later!


GnRH analog (but antagonist if used continuously)
(FA 596)

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