TIETZ FUNDAMENTALS OF CLINICAL
CHEMISTRY AND MOLECULAR DIAGNOSTICS
COMPLETE STUDY GUIDE AND LABORATORY
SCIENCE REVIEW 2026
◉ Porter-Silber.
Answer: 17-OHCS
◉ Rothera.
Answer: urinary ketones
◉ Benedict's/Clinitest.
Answer: urinary sugars
◉ Glucose oxidase.
Answer: glucose, peroxidase
◉ Hexokinase.
Answer: glucose, G6PD
◉ O-Toluidine.
,Answer: most specific non enzymatic sugar test
◉ Liebermann-Burchard.
Answer: total cholesterol
◉ Kjeldahl.
Answer: total protein based on nitrogen
◉ Biuret.
Answer: total protein, copper ions
◉ Mallow and Evelyn, Jendrassik-Grof.
Answer: serum bilirubin
◉ Hgb A1C.
Answer: Diabetes over long periods of time
◉ C-peptide.
Answer: differentiates between endogenous (peptide is present) and
exogenous insulin
◉ Jaffe method and creatininase.
,Answer: creatinine
◉ Uricase or Caraway.
Answer: uric acid
◉ PABA.
Answer: pancreatic function
◉ Trinder spot.
Answer: ASA
◉ Cherry and Crandall.
Answer: lipase
◉ Berthelot.
Answer: urea
◉ Increased AST and ALT.
Answer: hepatic damage
◉ Increased INR.
Answer: hepatic function problem
, ◉ Increased GGT and ALP, 5'NT.
Answer: hepatic obstruction problem
◉ Increased GGT.
Answer: ethanol intake
◉ Increased hgb A1C.
Answer: Diabetes
◉ C peptide.
Answer: endogenous insulin
◉ Increased BNP.
Answer: congestive heart failure
◉ Increased CK/AST/LD.
Answer: MI
◉ LD1>LD2.
Answer: MI
CHEMISTRY AND MOLECULAR DIAGNOSTICS
COMPLETE STUDY GUIDE AND LABORATORY
SCIENCE REVIEW 2026
◉ Porter-Silber.
Answer: 17-OHCS
◉ Rothera.
Answer: urinary ketones
◉ Benedict's/Clinitest.
Answer: urinary sugars
◉ Glucose oxidase.
Answer: glucose, peroxidase
◉ Hexokinase.
Answer: glucose, G6PD
◉ O-Toluidine.
,Answer: most specific non enzymatic sugar test
◉ Liebermann-Burchard.
Answer: total cholesterol
◉ Kjeldahl.
Answer: total protein based on nitrogen
◉ Biuret.
Answer: total protein, copper ions
◉ Mallow and Evelyn, Jendrassik-Grof.
Answer: serum bilirubin
◉ Hgb A1C.
Answer: Diabetes over long periods of time
◉ C-peptide.
Answer: differentiates between endogenous (peptide is present) and
exogenous insulin
◉ Jaffe method and creatininase.
,Answer: creatinine
◉ Uricase or Caraway.
Answer: uric acid
◉ PABA.
Answer: pancreatic function
◉ Trinder spot.
Answer: ASA
◉ Cherry and Crandall.
Answer: lipase
◉ Berthelot.
Answer: urea
◉ Increased AST and ALT.
Answer: hepatic damage
◉ Increased INR.
Answer: hepatic function problem
, ◉ Increased GGT and ALP, 5'NT.
Answer: hepatic obstruction problem
◉ Increased GGT.
Answer: ethanol intake
◉ Increased hgb A1C.
Answer: Diabetes
◉ C peptide.
Answer: endogenous insulin
◉ Increased BNP.
Answer: congestive heart failure
◉ Increased CK/AST/LD.
Answer: MI
◉ LD1>LD2.
Answer: MI