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What is the priority nursing action when a client receiving chemotherapy has an
absolute neutrophil count (ANC) below 500/mm³?
Answer: Initiate neutropenic precautions and assess for signs of infection
immediately.
Rationale: An ANC below 500/mm³ indicates severe neutropenia and a
significantly increased risk for life-threatening infection. The nurse should
implement protective precautions, monitor temperature closely, perform
frequent assessments for infection, encourage meticulous hand hygiene, and
avoid unnecessary invasive procedures. Fever in a neutropenic client is
considered a medical emergency requiring immediate intervention.
A client receiving chemotherapy reports a temperature of 38.4°C (101.1°F). What
should the nurse do first?
Answer: Notify the healthcare provider immediately.
Rationale: Fever during chemotherapy may indicate neutropenic sepsis, which can
rapidly become fatal. Immediate provider notification allows prompt initiation of
,blood cultures, intravenous antibiotics, and supportive therapy before the
infection progresses.
Which laboratory value is most important to review before administering
chemotherapy?
Answer: White blood cell count and absolute neutrophil count (ANC).
Rationale: Chemotherapy suppresses bone marrow function. Reviewing the WBC
count and ANC helps determine whether the client can safely receive treatment
or requires a delay due to increased infection risk.
A client with thrombocytopenia secondary to chemotherapy develops bleeding
gums. Which nursing intervention is appropriate?
Answer: Use a soft-bristled toothbrush and avoid flossing.
Rationale: Thrombocytopenia increases the risk for bleeding. Gentle oral care
minimizes trauma while maintaining oral hygiene. Hard toothbrushes, flossing,
and alcohol-based mouthwashes should be avoided.
What is the most common dose-limiting side effect of chemotherapy?
Answer: Bone marrow suppression.
, Rationale: Bone marrow suppression decreases production of white blood cells,
red blood cells, and platelets, increasing the risks for infection, anemia, and
bleeding. Careful monitoring of blood counts is essential throughout treatment.
A client receiving radiation therapy develops erythema over the treatment site.
What should the nurse recommend?
Answer: Wash the area gently with lukewarm water and mild soap if approved by
the radiation team.
Rationale: Radiation dermatitis is common. Gentle skin care reduces irritation
while preventing additional tissue injury. Harsh soaps, lotions not prescribed by
the provider, and adhesive tape should be avoided.
Which assessment finding suggests tumor lysis syndrome?
Answer: Elevated potassium, elevated uric acid, and elevated phosphorus levels.
Rationale: Tumor lysis syndrome occurs when cancer cells rapidly break down
after treatment, releasing intracellular contents into the bloodstream. This
metabolic emergency can result in cardiac dysrhythmias, acute kidney injury, and
seizures.
What medication is commonly administered to prevent tumor lysis syndrome?
Answer: Allopurinol.